Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yanhui Jia"'
Autor:
Yang Liu, Xiao-Qiang Li, Xujie Wang, Xiaozhi Bai, Shichao Han, Yanhui Jia, Dahai Hu, Jihong Shi, Kejia Wang, Mengyuan Cao, Julei Zhang, Fu Han
Publikováno v:
International Immunopharmacology. 63:220-226
MicroRNA-146a is a well-studied microRNA participating in immune and inflammatory diseases, but its role in sepsis has not been investigated. Here in our study, we found increased level of microRNA-146a in macrophage stimulated by lipopolysaccharide.
Autor:
Shichao Han, Fu Han, Dan Xiao, Dahai Hu, Xiao-Qiang Li, Yang Liu, Yanhui Jia, Xiaozhi Bai, Hao Guan, Zhenzhen Li, Weixia Cai, Kejia Wang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:784-792
Molecular mechanisms for macrophage immune responses modulated by SIRT1 during sepsis remain unclear. Here, we show that SIRT1 expression is down-regulated in macrophages from mouse sepsis model or LPS stimulation. SIRT1 expression in macrophages cor
Autor:
Shichao Han, Jiaqi Liu, Jun Li, Juntao Han, Yan Li, Jihong Shi, Xuekang Yang, Xiaozhi Bai, Dahai Hu, Hongtao Wang, Linlin Su, Na Li, Yanhui Jia
Publikováno v:
Innate Immunity. 23:188-195
The type III histone deacetylase SIRT1 has recently emerged as a critical immune regulator by suppressing T-cell immunity and macrophage activation during inflammation, but its mechanism in regulating inflammatory response in macrophages remains uncl
Autor:
Fu Han, Weixia Cai, Yongqiang Xu, Zhenzhen Li, Wanfu Zhang, Shichao Han, Dahai Hu, Yanhui Jia, Lijun Qi, Gaofeng Wu, Cong Li
Publikováno v:
Archives of biochemistry and biophysics. 668
Systemic inflammatory response syndrome (SIRS) is associated with excessive inflammatory response, however, the pathophysiology of inflammation is poorly understood. The retinoid-related orphan receptor α (RORα) is a key inflammatory regulator, but
Autor:
Kuan Yang, Weixia Cai, Yanhui Jia, Yunshu Yang, Chen Yang, Xiaozhi Bai, Dahai Hu, Xiao-Qiang Li, Shichao Han, Ji Peng, Zhenzhen Li, Wanfu Zhang, Gaofeng Wu
Publikováno v:
Journal of cellular physiology. 234(12)
The severity of sepsis is associated with excessive inflammatory responses. MCP-1 induced protein (MCPIP1) could negatively regulate inflammatory responses by deubiquitinating K48 or K63 polyubiquitins of TNF receptor-associated factors. The function
Autor:
Juntao Han, Hongyan Yang, Feng Gao, Jia Li, Jie Xu, Dahai Hu, Huayu Zhu, Wenjun Xie, Yanhui Jia, Xing Zhang, Xinghua Qin, Jun Li, Liang Zhu
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1865(2)
Background Acute hyperglycemia is regarded as a risk factor for critically ill patients; however, insufficient understanding of its nature and underlying mechanisms hinders widespread adoption of glycemic control in critical care units. Methods A sin