Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shuang Wen"'
Autor:
Hong Zhou, Yinling Li, Shuang Wen, Haitao Wang, Yeqin Sha, Longjun Li, Meiqing Shi, Qiang You, Yue Li, Lixin Liu
Publikováno v:
Theranostics
Rationale: Invariant natural killer T (iNKT) cells and Kupffer cells represent major hepatic populations of innate immune cells. However, their roles in steatohepatitis remain poorly understood. To elucidate their functions in steatohepatitis develop
Autor:
Weiguo Hu, Haitao Wang, Longjun Li, Yeqin Sha, Liang Sheng, Yinling Li, Hong Zhou, Lianping He, Shuang Wen
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(12)
Complement component C3, mainly synthesized by hepatocytes, acts as the convergence point of three different pathways in activating the complement cascade. Besides its well-established roles in the extracellular milieu, C3 performs various intracellu
Autor:
Muyang Gu, Guo-Ping Shi, Yuzhi Lu, Jingyong Li, Jiao Jiao, Ni Xia, Xiang-Ping Yang, Bingjie Lv, Shaofang Nie, Yu Hu, Dan Li, Shuang Wen, Tingting Tang, Xiang Cheng, Mengyang Liao, Yuhua Liao
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 39:446-458
Objective— Inflammation occurs during the progression of abdominal aortic aneurysm (AAA). IL (interleukin)-33 is a pleiotropic cytokine with multiple immunomodulatory effects, yet its role in AAA remains unknown. Approach and Results— Immunoblot,
Autor:
Jingyong Li, Ni Xia, Dan Li, Shuang Wen, Shirui Qian, Yuzhi Lu, Muyang Gu, Tingting Tang, Jiao Jiao, Bingjie Lv, Shaofang Nie, Desheng Hu, Yuhua Liao, Xiangping Yang, Guoping Shi, Xiang Cheng
Publikováno v:
Advanced Science. 9:2104338
In addition to maintaining immune tolerance, Foxp3
Autor:
Hong Zhou, Shuang Wen, Yeqin Sha, Qiang You, Haitao Wang, Liang Sheng, Lixin Liu, Lianping He, Fengjiao Wu, Jun Zhang, Longjun Li, Meiqing Shi
Publikováno v:
Cell Death Differ
Acetaminophen (APAP) is the leading cause of drug-induced acute liver failure. Sphingosine-1-phosphate (S1P), whose formation is catalyzed by sphingosine kinase (SPHK)-1 or -2, is a bioactive lipid implicated in human health and disease. Here, we sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5db4c5664a769e83a637e7519ef2df
https://europepmc.org/articles/PMC7244772/
https://europepmc.org/articles/PMC7244772/
Publikováno v:
Clinical and Experimental Immunology. 190:68-78
Summary Renal fibrosis is the common final manifestation of chronic kidney diseases and usually results in end-stage renal failure. In this study, we evaluated the effect of fingolimod (FTY720), an analogue of sphingosine 1-phosphate (S1P), as a trea
Autor:
Tieliang Ma, Daoyun Lei, Chao Han, Hong Zhou, Shitong Li, Songhui Xie, Shuang Wen, Li Liu, Lianping He
Publikováno v:
International Immunopharmacology. 80:106133
Background T help 2 (Th2) cell differentiation by morphine has been verified. However, the underlying mechanism of morphine induces Th2 cell differentiation remains elusive. The aim of the present study was to explore the possible basis of morphine i
Autor:
Hong Zhou, Dongyan Shi, Jiahui Lu, Shuang Wen, Xingxing Zhu, Shu Yao, Lixin Liu, Liao Xiang, Kelei Cao, Fengjiao Wu
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-12 (2018)
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-12 (2018)
Background Interleukin-33 (IL-33) is increasingly being recognized as a key immunomodulatory cytokine in many neurological diseases. Methods In the present study, wild-type (WT) and IL-33−/− mice received intracerebroventricular (i.c.v.) injectio
Autor:
Dongyan Shi, Shu Yao, Mingshun Zhang, Longjun Li, Shuang Wen, Xingxing Zhu, Kelei Cao, Tongguan Tian, Meiqing Shi, Hong Zhou
Publikováno v:
Brain, behavior, and immunity. 70
Neuropsychiatric (NP) involvement in systemic lupus erythematosus (SLE) severely impacts patients’ quality of life and leads to a poor prognosis. The current therapeutic protocol, corticosteroid administration, can also induce neuropsychiatric diso
Autor:
Dongyan Shi, Keqi Zhang, Shuang Wen, Lixin Liu, Fengjiao Wu, Qiang You, Xingxing Zhu, Yawei Zhao, Kelei Cao, Hong Zhou
Publikováno v:
Journal of leukocyte biology. 103(1)
Fingolimod (FTY720), an immunomodulator, is approved as an oral treatment for patients with relapsing forms of multiple sclerosis. Its effects are largely attributed to its mechanism of selectively retaining lymphocytes in the lymph nodes to reduce a