Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michael McDaniel"'
Autor:
Rodger P. McEver, Zhenghui Liu, Changgeng Ruan, Roberto Sonon, Jamey D. Marth, Samuel McGee, Yuji Kondo, Jianxin Fu, J. Michael McDaniel, Yannan Qin, Yun Li, Tadayuki Yago, Yun Ling, Christopher Hoover, Parastoo Azadi, Xia Bai, Bojing Shao, Jianhua Song, Lijun Xia
Publikováno v:
Proceedings of the National Academy of Sciences. 114:8360-8365
Most platelet membrane proteins are modified by mucin-type core 1-derived glycans (O-glycans). However, the biological importance of O-glycans in platelet clearance is unclear. Here, we generated mice with a hematopoietic cell-specific loss of O-glyc
Autor:
Andrew J. Morris, Lijun Xia, Bernhard Nieswandt, Florea Lupu, Robert Silasi-Mansat, Hong Chen, Minjia Sheng, Paul R. Hess, J. Michael McDaniel, Tadayuki Yago, Frauke May, Mark L. Kahn, Yanfang Pan, Stephen J. Wilson, Aslihan Sen, Brett H. Herzog, Shaun R. Coughlin, Jianxin Fu, Samuel McGee, Rodger P. McEver
Publikováno v:
Nature
Circulating lymphocytes continuously enter lymph nodes for immune surveillance through specialized blood vessels named high endothelial venules, a process that increases markedly during immune responses. How high endothelial venules (HEVs) permit lym
Autor:
Wenjia Xu, Megan L. Brophy, Satish Pasula, Hao Wu, Xiaofeng Cai, John McManus, Sukyoung Kwak, R. Sathish Srinivasan, Negar S. Rahman, Yunzhou Dong, John Michael Mcdaniel, Ye Sun, Baojun Chang, Hong Chen, Lijun Xia, H. N. Ashiqur Rahman, Aiyun Wen, Conrad Fernandes, Lois E.H. Smith, Kandice L. Tessneer
Publikováno v:
Circulation research. 118(6)
Rationale : We previously reported that vascular endothelial growth factor (VEGF)-induced binding of VEGF receptor 2 (VEGFR2) to epsins 1 and 2 triggers VEGFR2 degradation and attenuates VEGF signaling. The epsin ubiquitin interacting motif (UIM) was
Autor:
Maomeng Tong, Malin E. V. Johansson, Thomas J. Sferra, Jerrold R. Turner, Hong Chen, Xiaowei Liu, Kristina A. Thomsson, Samuel McGee, Bo Wei, Jonathan Braun, Lijun Xia, Tao Wen, Lilah Mansour, Gunnar C. Hansson, Emily M. Bradford, Jianxin Fu, J. Michael McDaniel
Publikováno v:
Journal of Clinical Investigation. 121:1657-1666
Mucin-type O-linked oligosaccharides (O-glycans) are primary components of the intestinal mucins that form the mucus gel layer overlying the gut epithelium. Impaired expression of intestinal O-glycans has been observed in patients with ulcerative col
Autor:
Lijun Xia, Markus Sperandio, Tadayuki Yago, J. Michael McDaniel, Richard D. Cummings, Sonia Pearson-White, Klaus Ley, Rodger P. McEver
Publikováno v:
The Journal of clinical investigation. 109(7)
P-selectin glycoprotein ligand-1 (PSGL-1) mediates rolling of leukocytes on P-selectin under flow. The glycoproteins that enable leukocyte tethering to or rolling on E-selectin are not known. We used gene targeting to prepare PSGL-1-deficient (PSGL-1