Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Jie Du"'
Autor:
Xue Li, Yue Sun, Jianjun Chang, Yan Chun Li, Zhe Xun, Hongguang Nie, Xinzhi Wei, Weicheng Liu, Jie Du, Xin Ge
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Idiopathic pulmonary fibrosis (IPF) is a severe disorder leading to progressive and irreversible loss of pulmonary function. In this study we investigated the anti-fibrotic effect of vitamin D using a mouse model of IPF. Lung fibrosis was induced wit
Publikováno v:
Journal of Cellular and Molecular Medicine
MicroRNA‐122 (miR‐122) is known to be up‐regulated by inflammation to exert a variety of biological functions in hepatocellular carcinoma (HCC)‐derived human cell lines. Vitamin D receptor (VDR) is reported to regulate excessive oral keratino
Publikováno v:
Circulation Research. 128:8-23
Rationale: Thoracic aortic aneurysm (TAA) leads to substantial mortality worldwide. Familial and syndromic TAAs are highly correlated with genetics. However, the incidence of sporadic isolated TAA (iTAA) is much higher, and the genetic contribution i
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1291-1305 (2020)
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1291-1305 (2020)
BACKGROUND Impaired muscle regeneration and increased muscle fibrosis are observed in aged muscle accompanied by progressive loss of muscle mass (sarcopenia). However, the underlying mechanism is still unclear. METHODS The differentiated expressed ge
Autor:
Jie Du, Yulin Li, Yihui Shao, Shan Huang, Bokang Qiao, Zhenfeng Li, Duanduan Chen, Ping Li, Guoqi Li, Huirong Liu
Publikováno v:
Cardiovascular Toxicology. 20:548-556
Vascular smooth muscle cells (VSMCs) shift from a physiological contractile phenotype to an adverse proliferative or synthetic state, which is a major event leading to aortic disease. VSMCs are exposed to multiple mechanical signals from their microe
Autor:
Yongxiang Wei, Yanwen Qin, Xiaolu Jiao, Song Yang, Linyi Li, Juan Li, Yunyun Yang, Jie Du, Lixin Jia, Yueli Wang, Xiao-ping Zhang
Publikováno v:
European Journal of Vascular and Endovascular Surgery. 59:1000-1010
Objectives Thoracic aortic dissection (TAD) has a high mortality rate. Intermittent hypoxia (IH) triggers both harmful and beneficial effects in numerous physiological systems. The effects of IH on TAD development were explored in a mouse model. Meth
Publikováno v:
Archives of Pharmacal Research. 42:1092-1100
Gestational diabetes mellitus (GDM) is a disease characterized by insufficient insulin secretion and glucose metabolic disorder during pregnancy. Tetramethylpyrazine has been reported to inhibit endoplasmic reticulum (ER) stress and high glucose-indu
Publikováno v:
Cardiovascular Research. 117:240-255
Aims Genetic contribution to coronary artery disease (CAD) remains largely unillustrated. Although transcriptomic profiles have identified dozens of genes that are differentially expressed in normal and atherosclerotic vessels, whether those genes ar
Autor:
Yu Bian, Xin Li, Ping Pang, Xue-ling Hu, Shu-ting Yu, Yi-ning Liu, Ning Wang, Jin-hui Wang, Wei Xiao, Wei-jie Du, Bao-feng Yang
Publikováno v:
Acta Pharmacologica Sinica
Pyroptosis is a form of inflammatory cell death that could be driven by the nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation following myocardial infarction (MI). Emerging eviden
Publikováno v:
Sheng li xue bao : [Acta physiologica Sinica]. 73(4)
The objective of this study was to explore the roles of arachidonic acid cytochrome P450ω hydroxylase CYP4A14 in skeletal muscle regeneration after injury. Wild-type (WT) control mice and Cyp4a14 knockout (A14