Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Guoping Shi"'
Autor:
Tuo Chen, Yugen Chen, Fan Bu, Rong Wang, Xiaomin Yuan, Jin-Yong Zhou, Zhenglan Duan, Zeyu Feng, Guoping Shi, Qiong Wang, Yang Ding, Sumin Zhang
Publikováno v:
Applied Microbiology and Biotechnology. 105:8411-8426
Major depressive disorder (MDD) is a neurasthenic disease, which is the second-largest burden of disease globally. Increasing studies have revealed that depression is associated with abnormalities in gut microbiota and metabolites. Several species of
Autor:
Rong Wang, Xiaomin Yuan, Guoping Shi, Fan Bu, Yang Ding, Yugen Chen, Zeyu Feng, Tuo Chen, Qiong Wang, Zhenglan Duan
Publikováno v:
Drug Design, Development and Therapy
Purpose Total flavone of Abelmoschus manihot (TFA), the effective constituents extracted from Flos Abelmoschus Manihot, has been reported to inhibit inflammation. However, the effect of TFA on ulcerative colitis (UC) progression in patients with depr
Total flavone of Abelmoschus Manihot improves colitis by promoting the growth of Akkermansia in mice
Autor:
Guoping Shi, Dan Zhang, Tuo Chen, Rong Wang, Jin-Yong Zhou, Yugen Chen, Yang Ding, Feng Jiang, Qiong Wang, Minmin Xu, Fan Bu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
The total flavone of Abelmoschus manihot (TFA), a compound extracted from the flowers of Abelmoschus manihot (L.) Medic, has been widely used for the treatment of Crohn's disease, chronic glomerulonephritis and other diseases. The aim of this study w
Autor:
Junxing Qu, Yanan Zhu, Xia Lu, Zhen Xu, Guoping Shi, Yayi Hou, Tingting Wang, Zhiyong Zhang, Sunan Shen, Yugen Chen, Tao Shi
Publikováno v:
EMBO J
Incorporation of microbiome data has recently become important for prevention, diagnosis, and treatment of colorectal cancer, and several species of bacteria were shown to be associated with carcinogenesis. However, the role of commensal fungi in col
Autor:
Jingyong Li, Ni Xia, Dan Li, Shuang Wen, Shirui Qian, Yuzhi Lu, Muyang Gu, Tingting Tang, Jiao Jiao, Bingjie Lv, Shaofang Nie, Desheng Hu, Yuhua Liao, Xiangping Yang, Guoping Shi, Xiang Cheng
Publikováno v:
Advanced Science. 9:2104338
In addition to maintaining immune tolerance, Foxp3
Publikováno v:
Journal of Cellular Physiology. 234:1618-1629
Accumulating evidence has shown that mammalian target of rapamycin (mTOR) pathway and myeloid-derived suppressor cells (MDSCs) are involved in pathogenesis of inflammatory bowel diseases (IBDs). INK128 is a novel mTOR kinase inhibitor in clinical dev
Autor:
Dan Li, Yayi Hou, Tingting Wang, Jingjing Qi, Genhong Yao, Yuchen Pan, Guoping Shi, Xuefang Zhang, Huan Dou
Publikováno v:
Molecular Medicine Reports
Interleukin (IL)-12 modulates the generation and function of various immune cells and plays a vital role in the pathogenesis of Sjögren's syndrome (SS). Myeloid-derived suppressor cells (MDSCs) are involved in autoimmune diseases by regulating vario
Autor:
Hongye Fan, Guoping Shi, Huan Dou, Yayi Hou, Yuchen Pan, Xiaojing Li, Xuefang Zhang, Jing Ren
Publikováno v:
Acta biochimica et biophysica Sinica. 50(9)
Inflammasomes are protein complexes responsible for the release of IL-1 family cytokines, and they play critical roles in immunity and inflammation. The best-characterized inflammasome, the NOD-like receptor protein 3 (NLRP3) inflammasome, is involve
Autor:
Jing Ren, Yayi Hou, Jianjian Ji, Xiaojing Li, Xuefang Zhang, Fei Liu, Liang Ding, Hongye Fan, Guoping Shi, Huan Dou
Publikováno v:
Cell Death & Disease
The increased death of macrophages has been considered as a pathogenic factor for systemic lupus erythematosus (SLE), and dysfunction of autophagy may contribute to improper cell death. However, the effect of autophagy on macrophage during the pathog