Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Franziska M. Uhl"'
Autor:
David, O'Sullivan, Michal A, Stanczak, Matteo, Villa, Franziska M, Uhl, Mauro, Corrado, Ramon I, Klein Geltink, David E, Sanin, Petya, Apostolova, Nisha, Rana, Joy, Edwards-Hicks, Katarzyna M, Grzes, Agnieszka M, Kabat, Ryan L, Kyle, Mario, Fabri, Jonathan D, Curtis, Michael D, Buck, Annette E, Patterson, Annamaria, Regina, Cameron S, Field, Francesc, Baixauli, Daniel J, Puleston, Edward J, Pearce, Robert, Zeiser, Erika L, Pearce
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Fever is a common symptom of infections and inflammation. We observed CD8+ T cells exposed to febrile-range temperature during activation, augmented mitochondrial mass, and metabolic activity. An adoptive transfer of these cells into tum
Autor:
Ramon I, Klein Geltink, Joy, Edwards-Hicks, Petya, Apostolova, David, O'Sullivan, David E, Sanin, Annette E, Patterson, Daniel J, Puleston, Nina A M, Ligthart, Joerg M, Buescher, Katarzyna M, Grzes, Agnieszka M, Kabat, Michal, Stanczak, Jonathan D, Curtis, Fabian, Hässler, Franziska M, Uhl, Mario, Fabri, Robert, Zeiser, Edward J, Pearce, Erika L, Pearce
Publikováno v:
Nature metabolism. 2(8)
CD8
Autor:
Shaima'a, Hamarsheh, Lena, Osswald, Benedikt S, Saller, Susanne, Unger, Donatella, De Feo, Janaki Manoja, Vinnakota, Martina, Konantz, Franziska M, Uhl, Heiko, Becker, Michael, Lübbert, Khalid, Shoumariyeh, Christoph, Schürch, Geoffroy, Andrieux, Nils, Venhoff, Annette, Schmitt-Graeff, Sandra, Duquesne, Dietmar, Pfeifer, Matthew A, Cooper, Claudia, Lengerke, Melanie, Boerries, Justus, Duyster, Charlotte M, Niemeyer, Miriam, Erlacher, Bruce R, Blazar, Burkard, Becher, Olaf, Groß, Tilman, Brummer, Robert, Zeiser
Publikováno v:
Nature Communications
Oncogenic Ras mutations occur in various leukemias. It was unclear if, besides the direct transforming effect via constant RAS/MEK/ERK signaling, an inflammation-related effect of KRAS contributes to the disease. Here, we identify a functional link b