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Autor:
Yi-You Huang, Din Ping Tsai, Hiroaki Misawa, Xu Shi, Cheng Hung Chu, Yu Hsin Chia, Mu Ku Chen, Sunil Vyas, Yuan Luo, Takuo Tanaka, Hsin Yu Kuo
Publikováno v:
Nano Letters. 21:5133-5142
Fluorescence microscopy with optical sectioning capabilities is extensively utilized in biological research to obtain three-dimensional structural images of volumetric samples. Tunable lenses have been applied in microscopy for axial scanning to acqu
Publikováno v:
Toxicology. 474
The plastic decomposition product microplastics (MPs) and the plastic additive Di (2-ethylhexyl) phthalate (DEHP) in the environment can damage various organs of the organism by inducing oxidative stress. The PI3K/AKT/mTOR signaling pathway participa
Autor:
Chisayo Kozuka, Vissarion Efthymiou, Vicencia M. Sales, Liyuan Zhou, Soravis Osataphan, Yixing Yuchi, Jeremy Chimene-Weiss, Christopher Mulla, Elvira Isganaitis, Jessica Desmond, Suzuka Sanechika, Joji Kusuyama, Laurie Goodyear, Xu Shi, Robert E. Gerszten, Cristina Aguayo-Mazzucato, Priscila Carapeto, Silvania DaSilva Teixeira, Darleen Sandoval, Direna Alonso-Curbelo, Lei Wu, Jun Qi, Mary-Elizabeth Patti
Publikováno v:
Diabetes
Epigenetic regulation is an important factor in glucose metabolism, but underlying mechanisms remain largely unknown. Here we investigated epigenetic control of systemic metabolism by bromodomain-containing proteins (Brds), which are transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b662548134f839e504197492e650fe
https://doi.org/10.2337/figshare.19064309
https://doi.org/10.2337/figshare.19064309
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 167
With the widespread use of plastics, microplastics (MPs) and di(2-ethylhexyl) phthalate (DEHP) have become emerging environmental pollutants. The combined toxicity of MPs and DEHP on the mouse pancreas and the specific mechanism of toxicity remain un
Autor:
Hao-ke Li, Ying-xu Shi, Yan-fei Gao, Zhongliang Deng, Yan-ji He, Yong Zhou, Dan Yang, Ren-yan Li
Publikováno v:
Biochemical and Biophysical Research Communications. 522:924-930
Lysine-specific demethylase 1 (LSD1) is a well characterized transcriptional regulator functioning on the chromatin to remove mono- and di-methyl groups from lysine 4 or lysine 9 of histone 3 (H3K4 or H3K9). LSD1 also has non-transcriptional activiti
Publikováno v:
The Science of the total environment. 821
Microplastics (MPs), as widespread hazardous substances in the environment, can cause potential adverse effects on biological health. However, reports on the toxic effects of different diameters MPs on urinary system are limited. Here, we investigate
Autor:
Yuan Luo, Ming Lun Tseng, Sunil Vyas, Hsin Yu Kuo, Cheng Hung Chu, Mu Ku Chen, Hsiang‐Chieh Lee, Wen‐Pin Chen, Vin‐Cent Su, Xu Shi, Hiroaki Misawa, Din Ping Tsai, Pan‐Chyr Yang
Publikováno v:
Small Methods. 6:2101228
Manipulation and precise delivery of optical energies in the regions of interest within specimens require different strategies. Hence, proper control of input beam parameters is a prerequisite. One of the prominent methods is metasurface optics, capa
Autor:
Paul S. de Vries, Sara Ture, Charles J. Lowenstein, Craig N. Morrell, J. Allen Bennett, Nicholas L. Smith, Sherry L. Spinelli, Ryan M. Burke, Xu Shi, Jennifer E. Huffman, Michael A. Mastrangelo, Robert E. Gerszten, Shannon G. Loelius, Charles O. Smith, Scott J. Cameron, Paul S. Brookes, Thomas E. Carey, Maria Sabater-Lleal, Rachel A. Berg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut dInvestigació Biomèdica Sant Pau (IIB Sant Pau)
Nature Communications
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut dInvestigació Biomèdica Sant Pau (IIB Sant Pau)
Genetic factors contribute to the risk of thrombotic diseases. Recent genome wide association studies have identified genetic loci including SLC44A2 which may regulate thrombosis. Here we show that Slc44a2 controls platelet activation and thrombosis
Publikováno v:
Cancer gene therapy. 28(10-11)
Hepatocellular carcinoma (HCC) is one of the most common malignancies and leading causes of cancer-related deaths globally. Despite significant advances in therapy, the molecular mechanisms underlying HCC development and progression remain unclear. H