Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Xiaomei Yuan"'
Autor:
Chenghong Sun, Hongbao Liang, Yun Zhao, Shirong Li, Xiangzi Li, Xiaomei Yuan, Guoliang Cheng, Yongkang Zhang, Mingfei Liu, Yongxia Guan, Jingchun Yao, Guimin Zhang
Publikováno v:
Journal of ethnopharmacology. 302
Jingfang Granule (JFG) is a Traditional Chinese Medicine prescription to empirically treat skin disease such as urticaria in clinical practice. However, the potential mechanisms of JFG on urticaria are not fully defined.The aim of this study is to in
Autor:
Xu Lu, Fu Li, Jinliang Chen, Haitao Xiang, Xiaomei Yuan, Haiyan He, Dan Wang, Zhuo Chen, Chao Huang
Publikováno v:
Behavioural Pharmacology. 32:62-72
We have reported that SMIP004, an inhibitor of S-phase kinase-associated protein 2 (Skp2), displays antidepressant-like activities in stress-naïve and chronically stressed mice. Here, we investigated the antidepressant-like effect of C1, another inh
Autor:
Bi-Huei Yang, Kristen Jepsen, Ke Wang, Xiaomei Yuan, Li-Fan Lu, Yan Liang, Shuo Wan, Wanqing Xu, Wenxian Fu, Sunglim Cho, Gen-Sheng Feng, Yi Dong, Hai-Hui Xue
Publikováno v:
Cell Reports, Vol 27, Iss 12, Pp 3629-3645.e6 (2019)
Cell reports, vol 27, iss 12
Cell reports
Cell reports, vol 27, iss 12
Cell reports
SUMMARY CD4+ Foxp3+ T regulatory (Treg) cells are key players in preventing lethal autoimmunity. Tregs undertake differentiation processes and acquire diverse functional properties. However, how Treg’s differentiation and functional specification a
Autor:
Huaxing Huang, Xiaomei Yuan, Chao Huang, Fu Li, Haiyan He, Jinliang Chen, Yaoying Ma, Dongjian Chen, Xiaoyou Wei, Zhuo Chen
Publikováno v:
Inflammation. 44(4)
Neuroinflammation and oxidative stress play critical roles in pathogenesis of depression. Diallyl disulfide (DADS), an active compound in garlic oil, has been shown to exhibit obvious anti-inflammatory and anti-oxidative activities. Preliminary evide
Autor:
Xiaomei Yuan, Chao Huang, Jiashu Lu, Zixuan Cai, Xu Lu, Lijuan Tong, Ting Ye, Zhuo Chen, Dan Wang
Publikováno v:
Neuropharmacology. 172
Previous studies have reported that macrophage-colony stimulating factor (M-CSF), a drug that is used to treat hematological system disease, can ameliorate chronic stress-induced depressive-like behaviors in mice. This indicates that M-CSF could be d
Publikováno v:
Physiology & Behavior. 224:113026
Posttraumatic stress disorder (PTSD) is a mental disorder that can translate into severe economic problems. Lycopene is an aliphatic hydrocarbon carotenoid extracted from plants, including papayas, tomatoes, and water melons. Previous studies have sh
Publikováno v:
The Journal of Immunology. 196:3665-3676
Resting central Tregs (cTregs) and activated effector Tregs (eTregs) are required for self-tolerance, but the heterogeneity and relationships within and between phenotypically distinct subsets of cTregs and eTregs are poorly understood. By extensive
Publikováno v:
Yuan, X; Dong, Y; Tsurushita, N; Tso, JY; & Fu, W. (2018). CD122 blockade restores immunological tolerance in autoimmune type 1 diabetes via multiple mechanisms. JCI Insight, 3(2). doi: 10.1172/jci.insight.96600. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/25q9f8x6
JCI insight, vol 3, iss 2
JCI insight, vol 3, iss 2
Signaling through IL-2/IL-15Rβ (CD122) is essential for the differentiation and function of T cells and NK cells. A mAb against CD122 has been implicated to suppress autoimmune type 1 diabetes (T1D) development in animal models. However, the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764a84971f7fc6bd1decd072db73fbee
http://www.escholarship.org/uc/item/25q9f8x6
http://www.escholarship.org/uc/item/25q9f8x6
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
How tissue-resident macrophages (TRM) impact adaptive immune responses remains poorly understood. We report novel mechanisms by which TRMs regulate T cell activities at tissue sites. These mechanisms are mediated by the complement receptor of immunog
Publikováno v:
The Journal of Immunology. 194:1334-1346
A network of mechanisms operates to maintain tolerance in the gut mucosa. Although CD103 marks many lymphoid cells within the gut, its direct functional role in intestinal tolerance is poorly understood. CD103 may be part of a redundant pathway, as C