Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Victoria Majam"'
Autor:
Irving L. Weissman, Winter A Okoth, Laughing Bear Torrez Dulgeroff, Sanjai Kumar, Michal Caspi Tal, Pallavi Malla, Victoria Majam, Maia Shoham, Joy Q He, Ying Ying Yiu, Miranda S. Oakley
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Novel therapies are urgently needed that can ameliorate the clinical syndromes of cerebral malaria, the most severe consequences of Plasmodium infection, and thereby reduce malaria fatality. Monoclonal antibodies that target CD47, a “d
Autor:
Martha Sedegah, Richard L. Shimp, Miranda S. Oakley, Victoria Majam, Arnel Belmonte, Bhavna Chawla, David C. Kaslow, Babita Mahajan, Sanjai Kumar
The development of effective malaria vaccines is hampered by incomplete understanding of the immunological correlates of protective immunity. Recently, the moderate clinical efficacy of the Plasmodium falciparum circumsporozoite protein (CSP)-based R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed838bd34e158368b145ec58064403bc
https://europepmc.org/articles/PMC6759290/
https://europepmc.org/articles/PMC6759290/
Autor:
Sanjai Kumar, Tanjir Islam, Sharareh Eskandari, Michael R. Batzloff, Istvan Toth, Mei Fong Ho, Victoria Majam, Danielle I. Stanisic, Ali Zaid, Hanan A Al-Nazal, Waleed M. Hussein, Mariusz Skwarczynski, Michael F. Good, Emily Cooper, Ashwini Kumar Giddam
Publikováno v:
Cell Host & Microbe. 29:894-903.e5
Babesia spp. are tick-transmitted intra-erythrocytic protozoan parasites that infect humans and animals, causing a flu-like illness and hemolytic anemia. There is currently no human vaccine available. People most at risk of severe disease are the eld
Autor:
Winter A. Okoth, Mark KuKuruga, Joanna K. Chorazeczewski, Adovi Akue, Maya Aleshnick, Regina Kurapova, Victoria Majam, Sanjai Kumar, Miranda S. Oakley
Recent studies have demonstrated that a subpopulation of neutrophils express the TCRαβ combinatorial immunoreceptor in humans and mice. Here, we report that a Plasmodium berghei ANKA murine malaria infection induces expansion of TCRβ expressing CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb4d5b81a5b2496cdee3bcac3294ab8
https://europepmc.org/articles/PMC6013678/
https://europepmc.org/articles/PMC6013678/
Autor:
Miranda S. Oakley, Adovi Akue, Joanna K. Chorazeczewski, Mark A. KuKuruga, Vivek Anantharaman, Qin Su, Sanjai Kumar, Bhavna Chawla, Victoria Majam, Winter A Okoth, Timothy G. Myers, L. Aravind, Maya Aleshnick, Kazuyo Takeda
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201043 (2018)
PLoS ONE
PLoS ONE
Macrophages express a wide array of invariant receptors that facilitate host defense and mediate pathogenesis during pathogen invasion. We report on a novel population of CD11bhighCD14+F4/80+ macrophages that express TCRβ. This population expands dr
Autor:
Thiago M. Venancio, Babita Mahajan, Vivek Anantharaman, Timothy G. Myers, L. Aravind, Sanjai Kumar, Victoria Majam, Hong Zheng, Miranda S. Oakley, Thomas F. McCutchan
Publikováno v:
Infection and Immunity. 79:1244-1253
Cerebral malaria (CM) is a primary cause of deaths caused by Plasmodium falciparum in young children in sub-Saharan Africa. Laboratory tests based on early detection of host biomarkers in patient blood would help in the prognosis and differential dia
Autor:
Sanjai Kumar, Jerrold M. Ward, Vivek Anantharaman, Victoria Majam, Laurence Faucette, Thomas F. McCutchan, Cindy R. Erexson, Hong Zheng, Babita Mahajan, L. Aravind, Miranda S. Oakley
Publikováno v:
Infection and Immunity. 76:4518-4529
Cerebral malaria (CM) is a primary cause of malaria-associated deaths among young African children. Yet no diagnostic tools are available that could be used to predict which of the children infected withPlasmodium falciparummalaria will progress to C
Autor:
Victoria Majam, Christian F. Ockenhouse, Anjali Yadava, Sanjai Kumar, Michael A Washington, Hong Zheng, Lisa A. Ware, Jetsumon Sattabongkot
Publikováno v:
Infection and Immunity. 75:1177-1185
A successful vaccine againstPlasmodium vivaxmalaria would significantly improve the health and quality of the lives of more than 1 billion people around the world. A subunit vaccine is the only option in the absence of long-term culture ofP. vivaxpar
Autor:
Yupin Charoenvit, Gary T. Brice, Jackie Williams, Victoria Majam, Daniel J. Carucci, Esteban Abot, Denise L. Doolan, David J. Bacon, Harini Ganeshan, Martha Sedegah, Daniel H. Zimmerman
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:2455-2463
CEL-1000 (DGQEEKAGVVSTGLIGGG) is a novel potential preventative and therapeutic agent. We report that CEL-1000 confers a high degree of protection against Plasmodium sporozoite challenge in a murine model of malaria, as shown by the total absence of
Autor:
Miranda S, Oakley, Bikash R, Sahu, Leda, Lotspeich-Cole, Victoria, Majam, Phuong, Thao Pham, Aditi, Sengupta Banerjee, Yukiko, Kozakai, Sheldon L, Morris, Sanjai, Kumar
Publikováno v:
European journal of immunology. 44(9)
CD4(+) T-cell subtypes govern the synthesis of different Ab isotypes and other immune functions. The influence of CD4(+) T-cell differentiation programs on isotype switching and other aspects of host immunological networks during malaria infection ar