Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Takashi Sono"'
Autor:
Stefano Negri, Kristen P. Broderick, Robert J. Tower, Aaron W. James, Min Lee, Jiajia Xu, Victoria Yu, Qizhi Qin, Yiyun Wang, Carolyn A. Meyers, Ginny Ching Yun Hsu, Masnsen Cherief, Takashi Sono, Seungyong Lee, Abhi Piplani
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 4, Pp 610-622 (2021)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Progenitor cells from adipose tissue are able to induce bone repair; however, inconsistent or unreliable efficacy has been reported across preclinical and clinical studies. Soluble inhibitory factors, such as the secreted Wnt signaling antagonists Di
Autor:
Jiajia Xu, Zhao Li, Robert J. Tower, Stefano Negri, Yiyun Wang, Carolyn A. Meyers, Takashi Sono, Qizhi Qin, Amy Lu, Xin Xing, Edward F. McCarthy, Thomas L. Clemens, Aaron W. James
Bone regeneration following injury is initiated by inflammatory signals and occurs in association with infiltration by sensory nerve fibers. Together, these events are believed to coordinate angiogenesis and tissue reprogramming, but the mechanism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85feffcb46a94fa919d0be2daeccd11e
http://hdl.handle.net/11562/1062398
http://hdl.handle.net/11562/1062398
Publikováno v:
Molecular pharmaceutics. 18(4)
Bone repair requires the tightly regulated control of multiple intrinsic and extrinsic cell types and signaling pathways. One of the positive regulatory signaling pathways in membranous and endochondral bone healing is the Hedgehog (Hh) signaling fam
Autor:
Stefano Negri, Yiyun Wang, Jiajia Xu, Bruno Péault, Masnsen Cherief, Aaron W. James, Ginny Ching Yun Hsu, Takashi Sono
Publikováno v:
J Orthop Res
Intra-articular injection of mesenchymal stem cells has shown benefit for the treatment of osteoarthritis (OA). However, mesenchymal stem/stromal cells at the origin of these clinical results are heterogenous cell populations with limited cellular ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299fe426bfa35e09857687f19e9dac75
http://hdl.handle.net/11562/1062222
http://hdl.handle.net/11562/1062222
Autor:
Zhu Li, Ye Tian, Stefano Negri, Thomas L. Clemens, Takashi Sono, Seungyong Lee, Aaron W. James, Liliana Minichiello, Sarah Miller, Carolyn A. Meyers, Leslie Chang, Jiajia Xu, Yongxing Gao, Yiyun Wang
Publikováno v:
Cell Reports, Vol 31, Iss 8, Pp-(2020)
Cell reports
Cell reports
SUMMARY The flat bones of the skull are densely innervated during development, but little is known regarding their role during repair. We describe a neurotrophic mechanism that directs sensory nerve transit in the mouse calvaria. Patent cranial sutur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681d561079de1e4a4eb81c6e53b17689
https://doi.org/10.1016/j.celrep.2020.107696
https://doi.org/10.1016/j.celrep.2020.107696
Autor:
Stefano Negri, Ching Yun Hsu, Jiajia Xu, Bruno Péault, Carolyn A. Meyers, Takashi Sono, Sarah Miller, Yiyun Wang, Aaron W. James
Publikováno v:
J Orthop Res
Pericytes ubiquitously surround capillaries and microvessels within vascularized tissues and have diverse functions after tissue injury. In addition to regulation of angiogenesis and tissue regeneration after injury, pericytes also contribute to orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7026b5d2663dc8fec64d7c06a03bed0e
https://europepmc.org/articles/PMC7483913/
https://europepmc.org/articles/PMC7483913/
Autor:
Takashi Sono, Jiajia Xu, Amanda K. Huber, Benjamin Levi, Simone Marini, Masnsen Cherief, Sarah Miller, Ching Yun Hsu, Bruno Péault, Aaron W. James, Yiyun Wang
Publikováno v:
Am J Pathol
Perivascular mural cells surround capillaries and microvessels and have diverse regenerative or fibrotic functions after tissue injury. Subsynovial fibrosis is a well-known pathologic feature of osteoarthritis, yet transgenic animals for use in visua
Autor:
Tadashi Kokubo, Koji Goto, Yaichiro Okuzu, Takayoshi Shimizu, Koji Yamamoto, Shuichi Matsuda, Seiji Yamaguchi, Bungo Otsuki, Tomiharu Matsushita, Takashi Sono, Shunsuke Fujibayashi
Publikováno v:
Acta biomaterialia. 63
We have previously developed the “alkali and heat treatment” method to confer bioactivity (bone-bonding ability) to titanium metal (Ti). As strontium (Sr) and magnesium (Mg) ions reportedly promote osteoblastic cell proliferation and differentiat