Zobrazeno 31 - 40
of 175
pro vyhledávání: '"Sun, Jin"'
Autor:
Pyeung-Hyeun Kim, Bo-Ra Jin, Jeong-Min Lee, Young-Saeng Jang, Woan-Sub Kim, Goo-Young Seo, Hekap Kim, H. Y. Seo, Sun-Jin Kim, Ki Jong Rhee, Seok-Rae Park, Hye-Ju Han
Publikováno v:
Mucosal Immunology. 8:906-917
Lactoferrin (LF), a pleiotropic iron-binding glycoprotein, is known to modulate the humoral immune response. However, its exact role in Ig synthesis has yet to be elucidated. In this study, we investigated the effect of LF on Ig production by mouse B
Autor:
Ki-Sun Park, Eun-Kyeong Jo, Jin-Man Kim, Vincent Giguère, Hye-Mi Lee, Tae Sung Kim, Hyo Sun Jin, Chul-Su Yang, Soo Yeon Kim, Jin Kyung Kim, Gi Ryang Kweon, Jean-Marc Vanacker, Catherine R. Dufour, Chul-Ho Lee, Jeongsu Han, Hueng-Sik Choi, David D. Moore, Jae-Min Yuk
Publikováno v:
Immunity
Immunity, 2015, 43 (1), pp.80-91. ⟨10.1016/j.immuni.2015.07.003⟩
Immunity, Elsevier, 2015, 43 (1), pp.80-91. ⟨10.1016/j.immuni.2015.07.003⟩
Immunity, 2015, 43 (1), pp.80-91. ⟨10.1016/j.immuni.2015.07.003⟩
Immunity, Elsevier, 2015, 43 (1), pp.80-91. ⟨10.1016/j.immuni.2015.07.003⟩
International audience; The orphan nuclear receptor estrogen-related receptor alpha (ERR alpha; NR3B1) is a key metabolic regulator, but its function in regulating inflammation remains largely unknown. Here, we demonstrate that ERRa negatively regula
Autor:
Jin Kyung Kim, Eun-Kyeong Jo, Soo Yeon Kim, Jae-Min Yuk, Tae Sung Kim, Chul-Su Yang, Hyo Sun Jin
Publikováno v:
The Journal of Immunology. 194:5355-5365
MicroRNAs (miRNAs) are small noncoding nucleotides that play critical roles in the regulation of diverse biological functions, including the response of host immune cells. Autophagy plays a key role in activating the antimicrobial host defense agains
Autor:
Lewis C. Cantley, Sun Jin Kim, Guang Gao, Jason W. Locasale, Yan Wang, Zhang Weihua, Tamar Melman, Lei Huo, Xuefeng Wu, John M. Asara, Jinyu Chen, James M. Briggs, Lei Xu, Fei Su, Ho Jeong Lee, Junqing He, Lakshmi Reddy Bollu, Isaiah J. Fidler, Xiaojing Liu
Publikováno v:
Cancer Research. 75:554-565
Breast cancer brain metastasis is resistant to therapy and a particularly poor prognostic feature in patient survival. Altered metabolism is a common feature of cancer cells, but little is known as to what metabolic changes benefit breast cancer brai
Autor:
Sun Jin Park, Kyoung Ja Kwon, Hye-Eun Lee, Ji Woong Choi, Daijin Kim, H. Heo, Yu Ho Lee, Jong-Hoon Ryu, Chan Young Shin
Publikováno v:
Neuroscience. 284:42-54
Throughout adulthood, neurons are continuously replaced by new cells in the dentate gyrus (DG) of the hippocampus, and this neurogenesis is increased by various neuronal injuries including ischemic stroke and seizure. While several mechanisms of this
Autor:
Soohyun Um, Eun-Kyeong Jo, Masaaki Komatsu, Yern-Hyerk Shin, Jin Kyung Kim, Tae Sung Kim, Dong-Chan Oh, Hye-Mi Lee, Jichan Jang, Guang-Ho Cha, Han-Jung Chae, Hyo Sun Jin, Jin Ho Choe
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
SCIENTIFIC REPORTS(7)
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
SCIENTIFIC REPORTS(7)
The induction of host cell autophagy by various autophagy inducers contributes to the antimicrobial host defense against Mycobacterium tuberculosis (Mtb), a major pathogenic strain that causes human tuberculosis. In this study, we present a role for
Autor:
Cristina Ivan, A. Gordon Robertson, Victoria K. Xie, Gabriel Lopez-Berenstein, Guermarie Velazquez-Torres, Li Huang, Einav Shoshan, Anil K. Sood, Harrison Paret, George A. Calin, Menashe Bar-Eli, Sun Jin Kim, Steven J.M. Jones, Enrique Fuentes-Mattei, Cristian Rodriguez-Aguayo, Denise Brooks
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Previously we have reported that metastatic melanoma cell lines and tumor specimens have reduced expression of ADAR1 and consequently are impaired in their ability to perform A-to-I microRNA (miRNA) editing. The effects of A-to-I miRNAs editing on me
The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy
Autor:
Soung Jung Kim, Minho Shong, Myung-Shik Lee, Ji-Hoon Park, Chul-Su Yang, Yong-Mahn Han, Gi Ryang Kweon, Jin-Man Kim, Eun-Kyeong Jo, Sang-Hee Lee, Hyo Sun Jin, J.W. Kim, Hye-Mi Lee
Publikováno v:
Autophagy. 10:785-802
AMP-activated protein kinase (AMPK) is a crucial energy sensor and plays a key role in integration of cellular functions to maintain homeostasis. Despite this, it is largely unknown whether targeting the AMPK pathway can be used as a therapeutic stra
Autor:
Gippeum Joy Lee, Tae Sung Kim, Yi Sak Kim, Jin-Man Kim, Soo Yeon Kim, Jun-Sang Kim, Jin Ho Choe, Hye-Mi Lee, Eui-Cheol Shin, Moon-June Cho, Sup Kim, Eun-Kyeong Jo, Hyo Sun Jin
Publikováno v:
Radiation research. 187(1)
During radiotherapy for tumors, the innate immune system also responds to ionizing radiation and induces immune modulation. However, little is known about the molecular mechanisms by which radiation modulates innate immune responses. In this study, w
Autor:
Eun-Kyeong Jo, Chul-Su Yang, Mingyu Jung, Jin Kyung Kim, Jichan Jang, Yi Sak Kim, Hye-Mi Lee, Goo Taeg Oh, Jin-Man Kim, Sup Kim, Hyo Sun Jin, Tae Sung Kim
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(8)
The role of peroxisome proliferator–activated receptor α (PPAR-α) in innate host defense is largely unknown. In this study, we show that PPAR-α is essential for antimycobacterial responses via activation of transcription factor EB (TFEB) transcr