Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sudheer Doss"'
Autor:
Richard C, Davis, Eric E, Schadt, Desmond J, Smith, Elena W Y, Hsieh, Alessandra C L, Cervino, Atila, van Nas, Melenie, Rosales, Sudheer, Doss, Haijin, Meng, Hooman, Allayee, Aldons J, Lusis
Publikováno v:
Genomics. 86:259-270
In the analysis of complex traits, congenic strains are powerful tools because they allow characterization of a single locus in the absence of genetic variation throughout the remainder of the genome. Here, we report the construction and initial char
Autor:
Aldons J. Lusis, Susanna Wang, Lawrence W. Castellini, Solveig K. Sieberts, Bin Zhang, Sudheer Doss, Anatole Ghazalpour, Chunsheng Zhang, Marie-France Champy, Steve Horvath, Valur Emilsson, Amy Leonardson, Pek Yee Lum, Jun Zhu, John Lamb, Stephen W. Edwards, Xia Yang, Shirly Pinto, Yanqing Chen, Douglas J. MacNeil, Thomas A. Drake, Eric E. Schadt
Publikováno v:
Nature
Nature, Nature Publishing Group, 2008, 452 (7186), pp.429-35. ⟨10.1038/nature06757⟩
Nature, Nature Publishing Group, 2008, 452 (7186), pp.429-35. ⟨10.1038/nature06757⟩
Identifying variations in DNA that increase susceptibility to disease is one of the primary aims of genetic studies using a forward genetics approach. However, identification of disease-susceptibility genes by means of such studies provides limited f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5234abb6c91171ec5bd885837316cef0
https://europepmc.org/articles/PMC2841398/
https://europepmc.org/articles/PMC2841398/
Publikováno v:
Genome research. 15(5)
We previously reported the analysis of genome-wide expression profiles and various diabetes-related traits in a segregating cross between inbred mouse strains C57BL/6J (B6) and DBA/2J (DBA). By considering transcript levels as quantitative traits, we
Autor:
Eleazar Eskin, Aldons J. Lusis, Alec J. Brozell, Anatole Ghazalpour, Ping-Zi Wen, Charles R. Farber, Desmond J. Smith, Sudheer Doss, Hyun Min Kang, Thomas A. Drake, Ruth Castellanos
Publikováno v:
Ghazalpour, A; Doss, S; Kang, H; Farber, C; Wen, PZ; Brozell, A; et al.(2008). High-resolution mapping of gene expression using association in an outbred mouse stock. PLoS Genetics, 4(8). doi: 10.1371/journal.pgen.1000149. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9w62w881
PLoS Genetics, Vol 4, Iss 8, p e1000149 (2008)
PLoS Genetics
PLoS Genetics, Vol 4, Iss 8, p e1000149 (2008)
PLoS Genetics
Quantitative trait locus (QTL) analysis is a powerful tool for mapping genes for complex traits in mice, but its utility is limited by poor resolution. A promising mapping approach is association analysis in outbred stocks or different inbred strains
Autor:
Ruth Castellanos, Aldons J. Lusis, Thomas A. Drake, Steve Horvath, Eric E. Schadt, Bin Zhang, Alec J. Brozell, Christopher L. Plaisier, Susanna Wang, Sudheer Doss, Anatole Ghazalpour
Publikováno v:
PLoS Genetics, Vol 2, Iss 8, p e130 (2006)
PLoS Genetics
PLoS Genetics
Systems biology approaches that are based on the genetics of gene expression have been fruitful in identifying genetic regulatory loci related to complex traits. We use microarray and genetic marker data from an F2 mouse intercross to examine the lar