Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Marsha Wills-Karp"'
Autor:
Koji Watanabe, Mahmoud M. Saleh, Mayuresh M. Abhyankar, Erica L. Buonomo, Stacey L. Burgess, Stephane Lajoie, Zannatun Noor, Marsha Wills-Karp, Carrie A. Cowardin, William A. Petri
Publikováno v:
Infection and Immunity. 84:2824-2832
Intestinal segmented filamentous bacteria (SFB) protect from ameba infection, and protection is transferable with bone marrow dendritic cells (BMDCs). SFB cause an increase in serum amyloid A (SAA), suggesting that SAA might mediate SFB's effects on
Autor:
Jordan Phelan, Ernst Malle, Naina Gour, Peter A. Tauber, Ursula Smole, Leonardo Puerta, Gerhard Hofer, Xiao Xiao, Luis Caraballo, Marsha Wills-Karp, Nu Yao, Bernhard Kratzer, Jan Dvorak, Cordula Köhler, Andrew P. Lane, Stephane Lajoie, Jamila Chakir, Sandra Rosskopf, Winfried F. Pickl
Publikováno v:
Nature immunology. 21(7)
The molecular basis for the propensity of a small number of environmental proteins to provoke allergic responses is largely unknown. Herein, we report that mite group 13 allergens of the fatty acid-binding protein (FABP) family are sensed by an evolu
Placental malperfusion in response to intrauterine inflammation and its connection to fetal sequelae
Autor:
Xiaobin Wang, Jun Lei, Julia L. Clemens, Han Xie, Marsha Wills-Karp, Solange N. Eloundou, Samar Al-Saggaf, Nita Nair, Bei Jia, Ahmet A. Baschat, Irina Burd, Ji Yeon Lee, Dan Wu, Ernest M. Graham, Yan Zhu, Michael W. McLane, Misun Hwang, Maide Ozen, Mia C. Feller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 4, p e0214951 (2019)
PLoS ONE, Vol 14, Iss 4, p e0214951 (2019)
Exposure to intrauterine inflammation (IUI) is associated with short- and long-term adverse perinatal outcomes. However, little data exist on utilizing placenta to prognosticate fetal injury in this scenario. Our study aimed to utilize imaging modali
Autor:
Stephane Lajoie, Xiao Xiao, Scott Huntsman, Yvonne Resch, Sam S. Oh, Anju Singh, Marquitta J. White, Marsha Wills-Karp, Ikhlass Haj Salem, Celeste Eng, Donglei Hu, Jung Hyun Kim, Angel C.Y. Mak, Naina Gour, Sophie Plante, Pagé C. Goddard, Ursula Smole, Esteban G. Burchard, Jamila Chakir, Annu Sharma, Nu Yao, Susanne Vrtala, Andrew P. Lane
Publikováno v:
Science immunology, vol 3, iss 20
The key factors underlying the development of allergic diseases-the propensity for a minority of individuals to develop dysfunctional responses to harmless environmental molecules-remain undefined. We report a pathway of immune counter-regulation tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eef67e9ee28432db09eb60d7b46e72d
https://escholarship.org/uc/item/8cr52118
https://escholarship.org/uc/item/8cr52118
Autor:
Marsha Wills-Karp
Publikováno v:
The Journal of clinical investigation. 127(12)
Food allergy occurs due to IgE- and mast cell–dependent intestinal inflammation. Previously, we showed that histamine-releasing factor (HRF), a multifunctional protein secreted during allergy, interacts with a subset of IgE molecules and that the H
Distinct Tlr4-expressing cell compartments control neutrophilic and eosinophilic airway inflammation
Autor:
Marsha Wills-Karp, Cheryl L. Rewerts, Gregory S. Whitehead, Christopher L. Karp, Donald N. Cook, Jaclyn W. McAlees, Fred D. Finkelman, Monica Cappelletti, Senad Divanovic, A M Holdcroft, Isaac T.W. Harley
Publikováno v:
Mucosal immunology
Allergic asthma is a chronic, inflammatory lung disease. Some forms of allergic asthma are characterized by T helper type 2 (Th2)-driven eosinophilia, whereas others are distinguished by Th17-driven neutrophilia. Stimulation of Toll-like receptor 4 (
Autor:
Anju Singh, Hwan Mee Yong, Ian P. Lewkowich, Naina Gour, Stephane Lajoie, Edward Gabrielson, Ursula Smole, Nu Yao, Marsha Wills-Karp
Publikováno v:
Mucosal immunology
Aberrant type 2 responses underlie the pathologies in allergic diseases like asthma, yet, our understanding of the mechanisms that drive them remains limited. Recent evidence suggests that dysregulated innate immune factors can perpetuate asthma path
Autor:
C. Conover Talbot, Irina Burd, Kuladeep Sudini, Thomas E. Sussan, Shyam Biswal, Xiaobin Wang, Marsha Wills-Karp
Publikováno v:
Scientific Reports
Preterm birth (PTB) is the leading cause of neonatal mortality, and surviving infants are at increased risk for lifelong disabilities. Intrauterine inflammation is an etiological factor that drives PTB, and oxidative stress is associated with PTB. Nu
Autor:
Fred D. Finkelman, Dirk E. Smith, Umasundari Sivaprasad, Evelyn A. Kurt-Jones, Krista Dienger, Paul J. Bryce, James G. Fox, Reena Rani, Ian P. Lewkowich, Gurjit K. Khurana Hershey, Lauren Lewis, De'Broski R. Herbert, Timothy C. Wang, Charles Perkins, Marsha Wills-Karp
Publikováno v:
Rockefeller UP
The Journal of Experimental Medicine
The Journal of Experimental Medicine
The repair protein trefoil factor 2 promotes Th2 responses to helminth infection and allergens in part by inducing IL-33.
The molecular mechanisms that drive mucosal T helper type 2 (TH2) responses against parasitic helminths and allergens remai
The molecular mechanisms that drive mucosal T helper type 2 (TH2) responses against parasitic helminths and allergens remai
Autor:
Charles Perkins, Lucy A. Gildea, Crystal Potter, Frank Brombacher, Marsha Wills-Karp, George Smulian, Bruce J. Aronow, Tatyana Orekov, Fred D. Finkelman, Noriko Yanase
Publikováno v:
The Journal of Experimental Medicine
IL-4Rα expression on airway smooth muscle cells is sufficient for the development of airway hyperresponsiveness.
Production of the cytokines IL-4 and IL-13 is increased in both human asthma and mouse asthma models, and Stat6 activation by the c
Production of the cytokines IL-4 and IL-13 is increased in both human asthma and mouse asthma models, and Stat6 activation by the c