Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mario Mancino"'
Autor:
Patricia Jauregui, Aleix Noguera-Castells, Raul Alonso, Silvia Menendez, Laia Serrano, Elisabet Ametller, Ana Lluch, L. Alex Gaither, Federico Rojo, Paloma Bragado, Pere Gascón, Leire Recalde-Percaz, Mario Mancino, Ana Rovira, Estel Enreig, Núria Moragas, Joan Albanell, Patricia Fernández-Nogueira, Vanessa Almendro, Anke Bill, Gemma Fuster, Anna López-Plana
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
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r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Purpose:Despite the therapeutic success of existing HER2-targeted therapies, tumors invariably relapse. This study aimed at identifying new mechanisms responsible for HER2-targeted therapy resistance.Experimental Design:We have used a platform of HER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e227e565ba327bbbd44f395147ae2e89
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4333
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4333
Autor:
Patricia Jauregui, Núria Moragas, Paloma Bragado, Leire Recalde-Percaz, Aleix Noguera-Castells, Estel Enreig, Pedro Gascón, Vanessa Almendro, Mario Mancino, Patricia Fernández-Nogueira, Gemma Fuster, Anna López-Plana, Neus Carbó
Publikováno v:
Cancer letters. 424
Histamine receptor 1 (HRH1) belongs to the rhodopsin-like G-protein-coupled receptor family. Its activation by histamine triggers cell proliferation, embryonic development, and tumor growth. We recently established that HRH1 is up-regulated in basal
Autor:
Kazuhide Watanabe, Enza Lonardo, Caterina Bianco, Luigi Strizzi, Andrew E. Arai, David S. Salomon, Tadahiro Nagaoka, Mario Mancino, Gabriella Minchiotti, Monica Gonzales, Christina Baraty, Colin Berry, Catherine Cotten
Publikováno v:
The American journal of pathology
175 (2009): 2146–2158. doi:10.2353/ajpath.2009.090218
info:cnr-pdr/source/autori:Bianco C.; Cotten C.; Lonardo E.; Strizzi L.; Baraty C.; Mancino M.; Gonzales M.; Watanabe K.; Nagaoka T.; Berry C.; Arai A.E.; Minchiotti G.; Salomon D.S./titolo:Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells/doi:10.2353%2Fajpath.2009.090218/rivista:The American journal of pathology (Print)/anno:2009/pagina_da:2146/pagina_a:2158/intervallo_pagine:2146–2158/volume:175
175 (2009): 2146–2158. doi:10.2353/ajpath.2009.090218
info:cnr-pdr/source/autori:Bianco C.; Cotten C.; Lonardo E.; Strizzi L.; Baraty C.; Mancino M.; Gonzales M.; Watanabe K.; Nagaoka T.; Berry C.; Arai A.E.; Minchiotti G.; Salomon D.S./titolo:Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells/doi:10.2353%2Fajpath.2009.090218/rivista:The American journal of pathology (Print)/anno:2009/pagina_da:2146/pagina_a:2158/intervallo_pagine:2146–2158/volume:175
Cripto-1 is a membrane-bound protein that is highly expressed in embryonic stem cells and in human tumors. in the present study, we investigated the effect of low levels of oxygen, which occurs naturally in rapidly growing tissues, on Cripto-1 expres
Autor:
Caterina Bianco, Kazuhide Watanabe, Monica Gonzales, Margaret Mysliwiec, Tadahiro Nagaoka, Mario Mancino, David S. Salomon
Publikováno v:
FEBS Letters. 582:3997-4002
Cripto-1, a co-receptor for Nodal, can activate Nodal-dependent and Nodal-independent signaling pathways. In this study we have investigated whether Cripto-1 mutants, that fail to activate a Nodal-dependent signaling pathway, are capable to activate
Regulation of human cripto-1 gene expression by TGF-β1 and BMP-4 in embryonal and colon cancer cells
Autor:
Nicola Normanno, Caterina Bianco, Kazuhide Watanabe, Monica Gonzales, Luigi Strizzi, Christian Wechselberger, Mario Mancino, Shin Hamada, David S. Salomon
Publikováno v:
Journal of Cellular Physiology. 215:192-203
Human Cripto-1 (CR-1) is a cell membrane protein that is overexpressed in several different types of human carcinomas. In the present study we investigated the mechanisms that regulate the expression of CR-1 gene in cancer cells. We cloned a 2,481 bp
Autor:
Raffaele Palaia, Nicola Normanno, Mario Mancino, Giuseppe D'Aiuto, David S. Salomon, Kazuhide Watanabe, Francesco Perrone, Shin Hamada, Gabriela A. Balogh, Daniel Mailo, Luigi Strizzi, Brenda Jones, Aasia O. Rehman, Gerardo Botti, Jose Russo, Antonella De Luca, Caterina Bianco
Publikováno v:
Clinical Cancer Research. 12:5158-5164
Purpose: Human Cripto-1 (CR-1), a cell membrane glycosylphosphatidylinositol-anchored glycoprotein that can also be cleaved from the membrane, is expressed at high levels in several different types of human tumors. We evaluated whether CR-1 is presen
Autor:
Luigi Strizzi, Mario Mancino, Nicola Normanno, Caterina Bianco, A. D'Antonio, S Lawson, Morihisa Hirota, David S. Salomon, Ahmed Raafat, Simona Losito, Shin Hamada, Andreas D. Ebert, Kazuhide Watanabe
Publikováno v:
The Journal of Pathology. 211:36-44
Overexpression of Cripto-1 (CR-1) in FVB/N mice using the MMTV-LTR promoter results in increased mammary tumourigenesis in these female transgenic mice (MMTV-CR-1). Here, we characterize uterine tumours that developed in 15/76 (19.7%) of MMTV-CR-1 fe
Autor:
Caterina Bianco, David S. Salomon, Ahmed Raafat, Brian W. Booth, Kazuhide Watanabe, Gilbert H. Smith, Monica Gonzales, Tadahiro Nagaoka, Beatrice A. Howard, Robert Callahan, David L. Mack, Luigi Strizzi, Mario Mancino
Publikováno v:
Journal of cellular physiology. 216(3)
Netrin-1 has been shown to regulate the function of the EGF-like protein Cripto-1 (Cr-1) and affect mammary gland development. Since Cr-1 is a target gene of Nanog and Oct4, we investigated the relationship between Netrin-1 and Cr-1, Nanog and Oct4 d
Autor:
Nicola, Normanno, Antonella, De Luca, Monica R, Maiello, Caterina, Bianco, Mario, Mancino, Luigi, Strizzi, Claudio, Arra, Fortunato, Ciardiello, Sudhir, Agrawal, David S, Salomon
Publikováno v:
International journal of oncology. 25(4)
Evidence suggests that CRIPTO-1 (CR-1) might be involved in the pathogenesis of human carcinoma. In the present study, we have screened the expression of CR-1 mRNA and protein in a wide panel of human cancer cell lines by using reverse transcriptase