Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Liping Wei"'
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Objective: The purpose of this study was to investigate the effect of dapagliflozin (DAPA), a sodium-glucose cotransporter 2 inhibitor, on relieving cardiac hypertrophy and its potential molecular mechanism.Methods: Cardiac hypertrophy induced by abd
Externí odkaz:
https://doaj.org/article/d7dacae71128438093e343c21c8eee9c
Autor:
Shundi Yao, Caicai Zhao, Zhigang Liu, Yutang Wang, Bing Ji, Shan Dong, Beita Zhao, Xuebo Liu, Liping Wei
Publikováno v:
Food & Function. 11:3952-3963
Secoisolariciresinol diglucoside (SDG) has positive effects on obesity and its complications. We investigated the effects and mechanism of SDG on high-fat and high-fructose diet (HFFD)-induced hepatic lipid metabolic disorders. Supplementation with 4
Publikováno v:
Cell Transplantation. 31:096368972211069
Hypoxia is a major regulator of tumor aggressiveness and metastasis in cancer progression. Exosomes (exos) play an important role in the communication between lung cancer and hypoxic microenvironment. However, the underlying mechanisms are largely un
Publikováno v:
Nucleic Acids Research
With advances in next-generation sequencing technologies, numerous novel transcripts in a large number of organisms have been identified. With the goal of fast, accurate assessment of the coding ability of RNA transcripts, we upgraded the coding pote
Publikováno v:
International Journal of Molecular Medicine
Patients with ischemic hearts who have refused coronary vascular reconstruction may exhibit dynamic myocardial remodeling and cardiac dysfunction. In the present study, the role of miRNA‑1 and its association with the ubiquitin‑proteasome system
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2015 (2015)
BioMed Research International, Vol 2015 (2015)
Oncostatin M (OSM) has been reported to stimulate angiogenesis by upregulating VEGF and bFGF, implying that it could be a therapeutic strategy in treating ischemic diseases. The present study was aimed at investigating whether OSM could improve cardi
Autor:
Bulan Wu, Yuan Yao, Yongcheng Song, Li Zhang, Lisheng Deng, Qianxing Mo, Liping Wei, Fengju Chen
Publikováno v:
Oncotarget
Histone lysine methylation regulates gene expression and cancer initiation. Bioinformatics analysis suggested that DOT1L, a histone H3-lysine79 (H3K79) methyltransferase, plays a potentially important role in breast cancer. DOT1L inhibition selective
Publikováno v:
Molecules, Vol 24, Iss 16, p 2916 (2019)
Molecules
Volume 24
Issue 16
Molecules
Volume 24
Issue 16
Resveratrol (RES) possesses anti-inflammatory and anti-oxidant activities, and it can prevent liver lipid metabolism disorders in obese and diabetic individuals. This study elucidated the mechanisms of brain and muscle Arnt-like protein-1 (Bmal1) in
Autor:
Zhenxing, Li, Sheng, He, Liping, Wei, Lin, Lin, Hanzhen, Xiong, Junhong, Li, Peifen, Chen, Wenyan, Lai
Publikováno v:
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 32(5)
To investigate the expression of reversion-inducing cysteine-rich protein with Kazal motifs (RECK) in the lung tissues of bronchial asthmatic mice and the effect of dexamethasone treatment on its expression.Thirty BALB/c mice were randomly divided in
Autor:
Mohammad Minhajuddin, Duane C. Hassane, Monica L. Guzman, Cheryl Corbett, Marlene Balys, Peter A. Crooks, Liping Wei, Siddhartha Sen, Craig T. Jordan, Randall M. Rossi
Publikováno v:
Blood. 116:5983-5990
We have previously shown that the plant-derived compound parthenolide (PTL) can impair the survival and leukemogenic activity of primary human acute myeloid leukemia (AML) stem cells. However, despite the activity of this agent, PTL also induces cell