Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Katia Befort"'
Publikováno v:
Behavioural Pharmacology
Behavioural Pharmacology, Lippincott, Williams & Wilkins, 2019, ⟨10.1097/FBP.0000000000000496⟩
Behavioural Pharmacology, Lippincott, Williams & Wilkins, 2019, pp.1. ⟨10.1097/FBP.0000000000000496⟩
Behavioural Pharmacology, Lippincott, Williams & Wilkins, 2019, ⟨10.1097/FBP.0000000000000496⟩
Behavioural Pharmacology, Lippincott, Williams & Wilkins, 2019, pp.1. ⟨10.1097/FBP.0000000000000496⟩
International audience; Binge eating in humans is driven by hedonic properties of food, suggesting that brain reward systems may contribute to this behaviour. We examined the role of mu opioid receptors (MOP) in binge eating by examining sweet soluti
Autor:
Katia Befort, Pauline Charbogne, Brigitte L. Kieffer, Ian Kitchen, Elena Martín-García, Dominique Filliol, Claire Gaveriaux-Ruff, Abdel-Mouttalib Ouagazzal, Helen L. Keyworth, Paul Chu Sin Chung, Emmanuel Darcq, Grégory Scherrer, Alexis Bailey, Audrey Matifas, Rafael Maldonado
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
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BACKGROUND: The delta opioid receptor (DOR) is broadly expressed throughout the nervous system; it regulates chronic pain, emotional responses, motivation, and memory. Neural circuits underlying DOR activities have been poorly explored by genetic app
Autor:
Veronica A. Alvarez, Ian Kitchen, Laura-Adela Harsan, Thomas Bienert, Anna E. Mechling, Elena Martín-García, Sami Ben Hamida, Alexis Bailey, Claire Gaveriaux-Ruff, Brigitte L. Kieffer, Alain Gratton, Anne Robé, Patricia Robledo, Helen L. Keyworth, Aya Matsui, Katia Befort, Jürgen Hennig, Dominik von Elverfeldt, Luc Moquin, Olivier Gardon, Emmanuel Darcq, Rafael Maldonado, Pauline Charbogne, Audrey Matifas, Taufiq Nasseef
Publikováno v:
Biological Psychiatry
Biological Psychiatry, 2017, 81 (9), pp.778-788. ⟨10.1016/j.biopsych.2016.12.022⟩
Recercat. Dipósit de la Recerca de Catalunya
instname
Biological Psychiatry, Elsevier, 2017, 81 (9), pp.778-788. ⟨10.1016/j.biopsych.2016.12.022⟩
Biological Psychiatry, 2017, 81 (9), pp.778-788. ⟨10.1016/j.biopsych.2016.12.022⟩
Recercat. Dipósit de la Recerca de Catalunya
instname
Biological Psychiatry, Elsevier, 2017, 81 (9), pp.778-788. ⟨10.1016/j.biopsych.2016.12.022⟩
BACKGROUND: Mu opioid receptors (MORs) are central to pain control, drug reward, and addictive behaviors, but underlying circuit mechanisms have been poorly explored by genetic approaches. Here we investigate the contribution of MORs expressed in gam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd61bd192d132426f7e8e3c7fed3b86
Publikováno v:
Neuropharmacology. 76:204-217
The endogenous opioid system is expressed throughout the brain reinforcement circuitry, and plays a major role in reward processing, mood control and the development of addiction. This neuromodulator system is composed of three receptors, mu, delta a
Autor:
André Hanauer, Katia Befort, Solange Pannetier, Emmanuel Darcq, Brigitte L. Kieffer, Claire Gaveriaux-Ruff, Pascale Koebel, Megan K. Mahoney
Publikováno v:
Neuropsychopharmacology. 37:1288-1296
It has been established that mu opioid receptors activate the ERK1/2 signaling cascade both in vitro and in vivo. The Ser/Thr kinase RSK2 is a direct downstream effector of ERK1/2 and has a role in cellular signaling, cell survival growth, and differ
Autor:
Katia Befort, André Hanauer, Brigitte L. Kieffer, Jean-Marie Garnier, Solange Pannetier, Pascale Koebel, Emmanuel Darcq, Carolina Del Boca, Anne-Sophie Kirstetter
Publikováno v:
Learning & Memory. 18:574-578
RSK2 is a Ser/Thr kinase acting in the Ras/MAPK pathway. Rsk2 gene deficiency leads to the Coffin-Lowry Syndrome, notably characterized by cognitive deficits. We found that mrsk2 knockout mice are unable to associate an aversive stimulus with context
Autor:
Olivier Poch, A. Ghate, Dominique Filliol, Aurélie Lardenois, Audrey Matifas, Christelle Thibault, Emmanuel Darcq, Jérôme A.J. Becker, J. Le Merrer, Doulaye Dembélé, Jean-Denis Muller, Katia Befort, Brigitte L. Kieffer
Publikováno v:
European Journal of Neuroscience. 27:2973-2984
Addiction develops from the gradual adaptation of the brain to chronic drug exposure, and involves genetic reprogramming of neuronal function. The central extended amygdala (EAc) is a network formed by the central amygdala and the bed nucleus of the
Autor:
Doulaye Dembélé, Emmanuel Darcq, Jean-Denis Muller, Aurélie Lardenois, Brigitte L. Kieffer, Olivier Poch, A. Ghate, Christelle Thibault, Dominique Filliol, Katia Befort, Audrey Matifas
Publikováno v:
Annals of the New York Academy of Sciences. 1129:175-184
The lateral hypothalamus (LH) is a brain structure that controls hedonic properties of both natural rewards and drugs of abuse. Mu opioid receptors are known to mediate drug reward, but whether overstimulation of these receptors impacts on LH functio
Publikováno v:
Psychopharmacology
Psychopharmacology, Springer Verlag, 2015, 232 (11), pp.1957-1971. ⟨10.1007/s00213-014-3826-5⟩
Psychopharmacology, 2015, 232 (11), pp.1957-1971. ⟨10.1007/s00213-014-3826-5⟩
Psychopharmacology, Springer Verlag, 2015, 232 (11), pp.1957-1971. ⟨10.1007/s00213-014-3826-5⟩
Psychopharmacology, 2015, 232 (11), pp.1957-1971. ⟨10.1007/s00213-014-3826-5⟩
Opiate addiction is a brain disorder emerging through repeated intoxication and withdrawal episodes. Epidemiological studies also indicate that chronic exposure to opiates may lead in susceptible individuals to the emergence of depressive symptoms, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad3eaf5a2996bcf971078c86cf2a378
https://hal.archives-ouvertes.fr/hal-02437502
https://hal.archives-ouvertes.fr/hal-02437502
Autor:
Aline Stéphan, Annie Boehrer, Brigitte L. Kieffer, Paul Chu Sin Chung, Emmanuel Darcq, Katia Befort, Audrey Matifas, Grégory Scherrer
The delta opioid receptor (DOR) has raised much interest for the development of new therapeutic drugs, particularly to treat patients suffering from mood disorders and chronic pain. Unfortunately, the prototypal DOR agonist SNC80 induces mild epilept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1466119e3a5e83704cf0e6e90f320daa
https://europepmc.org/articles/PMC4382405/
https://europepmc.org/articles/PMC4382405/