Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Joanna A. Phipps"'
Autor:
Elena Ivanova, Connie H Wong, Bang V. Bui, Gene Venables, Samuel A Mills, Michael A Dixon, Flora Hui, Zheng He, Kirstan A. Vessey, Vickie Hy Wong, Josh Tonc, James C Young, Botir T. Sagdullaev, Andrew I Jobling, Ursula Greferath, Erica L. Fletcher, Joanna A. Phipps
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance This work identifies a role for microglia, the innate immune cells of the CNS, in the local control of the retinal vasculature and identifies deficits early in diabetes. Microglia contact neurons and vasculature and express several vasoa
Autor:
Alexandra Grubman, Anthony R. White, Kirstan A. Vessey, Joanna A. Phipps, Andrew I Jobling, Philipp von Eisenhart-Rothe, Ursula Greferath, Linda J Fothergill, Erica L. Fletcher
Publikováno v:
Investigative ophthalmologyvisual science. 59(12)
Purpose Vision loss caused by photoreceptor death represents one of the first symptoms in neuronal ceroid lipofuscinosis, a condition characterized by accumulation of intracellular waste. Cln6nclf mice have a naturally occurring mutation in ceroid-li
Autor:
Kirstan A, Vessey, Ben J, Gu, Andrew I, Jobling, Joanna A, Phipps, Ursula, Greferath, Mai X, Tran, Michael A, Dixon, Paul N, Baird, Robyn H, Guymer, James S, Wiley, Erica L, Fletcher
Publikováno v:
The American journal of pathology. 187(8)
Age-related macular degeneration (AMD) is a leading cause of irreversible, severe vision loss in Western countries. Recently, we identified a novel pathway involving P2X7 receptor scavenger function expressed on ocular immune cells as a risk factor f
Autor:
Robb U. de Iongh, Tracy Ho, Ursula Greferath, Erica L. Fletcher, Andrew I Jobling, Kirstan A. Vessey, Samuel A Mills, Joanna A. Phipps, Michelle Waugh
Publikováno v:
Optometry and Vision Science
Over the recent years, there have been tremendous advances in our understanding of the genetic and environmental factors associated with the development of age-related macular degeneration (AMD). Examination of retinal changes in various animals has
Autor:
Joanna A. Phipps, Erica L. Fletcher, Mai X. Tran, Andrew I Jobling, Nupur Nag, Alice Brandli, Kirstan A. Vessey
Publikováno v:
Investigative Opthalmology & Visual Science. 59:487
Purpose: This study explored whether the proangiogenic factor Angiotensin II (AngII) had a direct effect on the activation state of microglia via the Angiotensin type 1 receptor (AT1-R). Methods: Microglial dynamic activity was investigated in live r
Autor:
Erica L. Fletcher, Lidia Trogrlic, Andrew I Jobling, Kirstan A. Vessey, Ursula Greferath, Joanna A. Phipps, Michelle Waugh, Tracy Ho
Publikováno v:
Investigative ophthalmologyvisual science. 56(2)
PURPOSE: The chemokine Ccl2, or monocyte chemoattractant protein-1 (MCP-1), has previously been identified as playing a potential role in many ocular diseases; however, its role in mice is less clear. We sought to correlate changes in retinal pigment
Diabetic retinopathy is the most common microvascular complication caused by diabetes mellitus and is a leading cause of vision loss among working-age adults in developed countries. Understanding the effects of diabetes on the retinal proteome may pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37d03c701a931777c005bea6fccb75b
https://europepmc.org/articles/PMC2798584/
https://europepmc.org/articles/PMC2798584/
Autor:
Erica L. Fletcher, Jenny M. Gunnersen, Joanna A. Phipps, Seong-Seng Tan, Vicki E. Hammond, Theresa Puthussery, Annabel Kuek
Publikováno v:
PloS one, vol 4, iss 8
PLoS ONE
PLoS ONE, Vol 4, Iss 8, p e6546 (2009)
PLoS ONE
PLoS ONE, Vol 4, Iss 8, p e6546 (2009)
BackgroundSeizure-related gene 6 (Sez-6) is expressed in neurons of the mouse brain, retina and spinal cord. In the cortex, Sez-6 plays a role in specifying dendritic branching patterns and excitatory synapse numbers during development.Methodology/pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056026898cef992fc675439ca0fcf177
https://escholarship.org/uc/item/4ws4z108
https://escholarship.org/uc/item/4ws4z108
Autor:
Michelle Waugh, Andrew I Jobling, Kirstan A. Vessey, Tracy Ho, Erica L. Fletcher, Ursula Greferath, Joanna A. Phipps
Publikováno v:
Investigative Opthalmology & Visual Science. 53:7833
Purpose The chemokine, Ccl2, and the fractalkine receptor, Cx3cr1, have both been implicated in the pathogenesis of age related macular degeneration (AMD), with mice lacking both genes exhibiting features of AMD by 3 months of age. However, recent re