Zobrazeno 1 - 10
of 597
pro vyhledávání: '"Jing Zhao"'
Autor:
Qijing Wu, Wei Li, Jing Zhao, Wei Sun, Qianqian Yang, Chong Chen, Ping Xia, Jingjing Zhu, Yiceng Zhou, Guoshun Huang, Chen Yong, Min Zheng, Enchao Zhou, Kun Gao
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss , Pp 111308- (2021)
Background and objective: Doxorubicin (DOX) is an anthracycline antitumor antibiotic widely utilized in treating various tumors. Nevertheless, the toxicity of DOX toward normal cells limits its applicability, with nephrotoxicity considered a major do
Externí odkaz:
https://doaj.org/article/bdd67b39ad93436f8794203de2970b27
Autor:
Peng Du, Jianbin Xu, Yanfei Jiang, Jing Zhao, Chaoqun Gao, Yudie Fang, Xiaorong Yang, Yan-ping Yang, Jin-an Zhang
Publikováno v:
Journal of Immunology Research. 2022:1-12
Objective. Hashimoto’s thyroiditis (HT) is one of the most common clinical autoimmune diseases. Recent studies have found that HT pathogenesis is associated with macrophage polarization. Saikosaponin-d (SSd) is an active component in the Chinese me
Autor:
Yangying Jia, Jianhai Chen, Jie Zhong, Xuefei He, Li Zeng, Yanmin Wang, Jiakun Li, Shengqian Xia, Erdengqieqieke Ye, Jing Zhao, Bin Ke, Chunyu Li
Publikováno v:
Clinical Genetics. 103:79-86
Hypoplastic left heart syndrome (HLHS) is a rare but fatal birth defect in which the left side of the heart is underdeveloped. HLHS accounts for 2% to 4% of congenital heart anomalies. Whole genome sequencing (WGS) was conducted for a family trio con
Publikováno v:
Microbial Biotechnology. 15:2786-2799
Endometritis is persistent inflammation caused by bacteria, which can lead to infertility. Although traditional Chinese medicine (TCM) has been used to treat endometritis, the underlying mechanism is still unclear. Here, Baogong Decoction (BGD), a TC
Autor:
Miaojuan Qiu, Junzong Chen, Xiuyu Huang, Binbin Li, Shiqiang Zhang, Peng Liu, Qiang Wang, Zhi Rong Qian, Yihang Pan, Yu Chen, Jing Zhao
Publikováno v:
ACS Applied Materials & Interfaces. 14:21954-21965
Ovarian cancer is a common gynecologic malignancy with a high fatality rate. Intraperitoneal chemotherapy has been proved as an efficient clinical treatment for disseminated ovarian cancer. However, there are limitations for conventional small molecu
Autor:
Yuzhi Xu, Si‐Yang Liu, Leli Zeng, Hansu Ma, Yanfei Zhang, Huihui Yang, Yuchen Liu, Shuo Fang, Jing Zhao, Yunsheng Xu, Charles R. Ashby, Yulong He, Zong Dai, Yihang Pan
Publikováno v:
Advanced Materials. 35
Cuproptosis, a newly identified form of regulated cell death that is copper-dependent, offers great opportunities for exploring the use of copper-based nanomaterials inducing cuproptosis for cancer treatment. Here, a glucose oxidase (GOx)-engineered
Autor:
Xiao-Jing Zhao, Hai-Yan Zhu, Xiao-Liang Wang, Xiao-Wei Lu, Cai-Long Pan, Lu Xu, Xue Liu, Ning Xu, Zhi-Yuan Zhang
Publikováno v:
Journal of Neurotrauma. 39:530-543
Traumatic brain injury (TBI) is a global public health concern, and few effective treatments for its delayed damages are available. Oridonin (Ori) recently has been reported to show a promising neuroprotective efficacy, but its potential therapeutic
Autor:
Jie Zhang, Lina Zhang, Jianlong Wang, Jing Zhao, Xuelian Zhao, Chunli Zhang, Peng Han, Cuizhi Geng
Publikováno v:
Human Cell. 35:909-923
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. Dysregulation of long non-coding RNAs (lncRNAs) plays crucial roles in the initiation and progression of TNBC. In this study, we analyzed public GEO profiles to ver
Autor:
Cunxiang Ju, Juan Liang, Mingkun Zhang, Jinlong Zhao, Ling’en Li, Shuai Chen, Jing Zhao, Xiang Gao
Publikováno v:
Mammalian Genome. 33:143-156
Mouse models are essential for dissecting disease mechanisms and defining potential drug targets. There are more than 18,500 mouse strains available for research communities in National Resource Center for Mutant Mice (NRCMM) of China, affiliated wit
Autor:
Wen-Zhang, Dai, Zhao-Fang, Bai, Ting-Ting, He, Xiao-Yan, Zhan, Qiang, Li, Jing, Zhao, Xiao-He, Xiao
Publikováno v:
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 47(19)
Excess acetaminophen(APAP) can be converted by the cytochrome P450 system to the toxic metabolite N-acetyl-p-benzoquinoneimine(NAPQI), which consumes glutathione(GSH). When GSH is depleted, NAPQI covalently binds with proteins, inducing mitochondrial