Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Hiroyuki Inoue"'
Autor:
Tomoka Tabata, Yuki Masumura, Shuichiro Higo, Suzuka Kunimatsu, Satoshi Kameda, Hiroyuki Inoue, Shota Okuno, Shou Ogawa, Seiji Takashima, Mikio Watanabe, Shigeru Miyagawa, Shungo Hikoso, Yasushi Sakata
Publikováno v:
Biochemical and Biophysical Research Communications. 637:40-49
Kinetic analysis of intracellular calcium (Ca
Autor:
Kanar Alkass, Ayumi Motomura, Namiko Ishii, Keisuke Okaba, Hiroki Tanaka, Hiroyuki Inoue, Daisuke Yajima, Shinnosuke Yamada, Henrik Druid, Kie Horioka
Publikováno v:
Thrombosis Research. 205:47-55
Background Accidental hypothermia results in various dysfunctions in the human body. Additionally, coagulation disorder can lead to a life-threatening condition. We previously demonstrated that platelets stored in the spleen were activated and thus t
Autor:
Shigehiro Tohyama, Masayuki Igarashi, Kazuaki Matoba, Ryuichi Sawa, Hiroyuki Inoue, Hideyuki Muramatsu, Manabu Kawada, Masaki Hatano
Publikováno v:
The Journal of Antibiotics. 74:743-751
Specific inhibitors of protein phosphatase 2A (PP2A) mediate anticancer effects by augmenting the tumor-killing activity of natural killer (NK) cells. In this study, new PP2A inhibitors, aminocytostatins A-E, were isolated from Kitasatospora sp. MJ65
Autor:
Teizo Asano, Takuro Nakamura, Hideki Hosono, Manabu Kawada, Yusuke Sayama, Hiroyoshi Suzuki, Yukinari Kato, Tomokazu Ohishi, Junko Takei, Hiroyuki Inoue, Mika K. Kaneko, Masato Sano
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 39:167-174
Podoplanin (PDPN), a 36-kDa type I transmembrane O-glycoprotein, is expressed in normal cells, including renal epithelial cells (podocytes), lymphatic endothelial cells, and pulmonary type I alveol...
Autor:
Manabu Kawada, Hiroyuki Inoue, Mirza S. Baig, Shun-ichi Ohba, Hikaru Abe, Tomokazu Ohishi, Takumi Watanabe, Uzma Saqib, Chiharu Sakashita, Masakatsu Shibasaki
Publikováno v:
International Journal of Cancer. 146:3474-3484
Modulation of prostate stromal cells (PrSCs) within tumor tissues is gaining attention for the treatment of solid tumors. Using our original in vitro coculture system, we previously reported that leucinostatin (LCS)-A, a peptide mycotoxin, inhibited
Autor:
Manabu Kawada, Hiroyuki Inoue, Satoshi Ogasawara, Shun Ichi Ohba, Yukinari Kato, Sakiko Urano, Masunori Kajikawa, Mika K. Kaneko, Shuichi Sakamoto
Publikováno v:
Cancer Science
Coxsackievirus and adenovirus receptor (CAR) is a single‐pass transmembrane protein that is associated with adenoviral infection. CAR is involved in the formation of epithelial tight junctions and promotes tumor growth in some cancers. Previously,
Autor:
Hiroyuki Inoue, Yuto Takishima, Mutsunori Murahashi, Shohei Miyamoto, Hisanobu Ogata, Hiroyuki Shimizu, Beibei Wang, Yoichi Nakanishi, Kenzaburo Tani, Toshihiko Okazaki, Yasuki Hijikata, Kazunari Yamada, Masaki Kuroda
Publikováno v:
Anticancer Research. 38:6121-6126
Background Colorectal cancer (CRC) is a major cause of morbidity and mortality throughout the world. It is the third most common cancer worldwide and the fourth most common cause of cancer-related death. FOLFOX, a combination of leucovorin calcium, f
Autor:
Toshiyuki Kosuga, Kazuma Okamoto, Hirotaka Konishi, Tomohiro Arita, Hisashi Ikoma, Atsushi Shiozaki, Tomoki Konishi, Katsutoshi Shoda, Shuhei Komatsu, Eigo Otsuji, Hitoshi Fujiwara, Michihiro Kudou, Ryo Morimura, Kento Kurashima, Hiroyuki Inoue, Atsushi Toma, Takeshi Kubota
Publikováno v:
International Journal of Oncology
The targeting of membrane proteins that are activated in cancer stem cells (CSCs) represents one of the key recent strategies in cancer therapy. The present study analyzed ion channel expression profiles and functions in pancreatic CSCs (PCSCs). Cell
Autor:
Hiroyuki Inoue, Taketoshi Mizutani, Shun-ichi Ohba, Shuichi Sakamoto, Yasuko Kohda, Manabu Kawada
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4934, p 4934 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 14
International Journal of Molecular Sciences
Volume 21
Issue 14
Small cell lung cancer (SCLC) is a severe malignancy associated with early and widespread metastasis. To study SCLC metastasis, we previously developed an orthotopic transplantation model using the human SCLC cell line DMS273. In the model, metastati
Autor:
Akiko Kubo, Kentaro Fujii, Makoto Suematsu, Yasuaki Kabe, Takako Hishiki, Masanori Tamaki, Noriyo Hayakawa, Kazutoshi Miyashita, Hiroshi Itoh, Masaaki Sato, Aika Hagiwara, Masaki Ryuzaki, Hiroyuki Inoue
Publikováno v:
JCI Insight. 4
Although oxidative stress plays central roles in postischemic renal injury, region-specific alterations in energy and redox metabolism caused by short-duration ischemia remain unknown. Imaging mass spectrometry enabled us to reveal spatial heterogene