Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Goutam Chakraborty"'
Autor:
Joshua A. Korsen, Teja M. Kalidindi, Samantha Khitrov, Zachary V. Samuels, Goutam Chakraborty, Julia A. Gutierrez, John T. Poirier, Charles M. Rudin, Yu Chen, Michael J. Morris, Nagavarakishore Pillarsetty, Jason S. Lewis
Publikováno v:
J Nucl Med
Treatment-induced neuroendocrine prostate cancer (NEPC) is a lethal subtype of castration-resistant prostate cancer. Using the (89)Zr-labeled delta-like ligand 3 (DLL3) targeting antibody SC16 ((89)Zr-desferrioxamine [DFO]-SC16), we have developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e196a4ac7a53b8ebcbf7ef317673a9
https://europepmc.org/articles/PMC9454466/
https://europepmc.org/articles/PMC9454466/
Autor:
Myrto Skafida, Scott T. Tagawa, Naga Vara Kishore Pillarsetty, Neil H. Bander, Neeta Pandit-Taskar, Teja Kalidindi, Joseph R. Osborne, Sang-Gyu Lee, Steven M. Larson, Jason S. Lewis, Heiko Schöder, Katerina Jou, Goutam Chakraborty, Lisa Bodei
Publikováno v:
Eur J Nucl Med Mol Imaging
Peptide-based prostate-specific membrane antigen (PSMA) targeted radionuclide therapy (TRT) agent [177Lu]-PSMA-617 has emerged as leading TRT candidate for treatment of castration-resistant prostate cancer (mCRPC). [177Lu]-PSMA-617 and other small mo
Autor:
Hyunho Han, Yan Wang, Josue Curto, Sreeharsha Gurrapu, Sara Laudato, Alekya Rumandla, Goutam Chakraborty, Xiaobo Wang, Hong Chen, Yan Jiang, Dhiraj Kumar, Emily G. Caggiano, Monica Capogiri, Boyu Zhang, Yan Ji, Sankar N. Maity, Min Hu, Shanshan Bai, Ana M. Aparicio, Eleni Efstathiou, Christopher J. Logothetis, Nicholas Navin, Nora M. Navone, Yu Chen, Filippo G. Giancotti
Publikováno v:
Cell Reports. 39:110595
Bioinformatic analysis of 94 patient-derived xenografts (PDXs), cell lines, and organoids (PCOs) identifies three intrinsic transcriptional subtypes of metastatic castration-resistant prostate cancer: androgen receptor (AR) pathway + prostate cancer
Autor:
Goutam, Chakraborty, Nabeela Khan, Patail, Rahim, Hirani, Subhiksha, Nandakumar, Ying Z, Mazzu, Yuki, Yoshikawa, Mohammad, Atiq, Lina E, Jehane, Konrad H, Stopsack, Gwo-Shu Mary, Lee, Wassim, Abida, Michael J, Morris, Lorelei A, Mucci, Daniel, Danila, Philip W, Kantoff
Publikováno v:
Clin Cancer Res
PURPOSE: Alterations in DNA damage repair (DDR) pathway genes occur in 20–25% of men with metastatic castration-resistant prostate cancer (mCRPC). Although poly (adenosine diphosphate [ADP]-ribose) polymerase inhibitors (PARPi) have been shown to b
Autor:
Ying Z. Mazzu, Nabeela Khan, Edward P. O’Connor, Goutam Chakraborty, Kazumasa Komura, Matthew L. Freedman, Baek Kim, Henry W. Long, Joshua Armenia, Si'Ana A. Coggins, Subhiksha Nandakumar, Philip W. Kantoff, Yuki Yoshikawa, Huiyong Zhao, Connor Bell, Xintao Qiu, Travis Gerke, Mark Pomerantz, Mohammad Omar Atiq, Gwo-Shu Mary Lee, Samson W. Fine
Publikováno v:
Clin Cancer Res
Purpose: Defects in genes in the DNA repair pathways significantly contribute to prostate cancer progression. We hypothesize that overexpression of DNA repair genes may also drive poorer outcomes in prostate cancer. The ribonucleotide reductase small
Autor:
Hua Gao, Ai Ping Lee-Lim, Filippo G. Giancotti, Goutam Chakraborty, Konstantinos J. Mavrakis, Hans-Guido Wendel
Publikováno v:
Proceedings of the National Academy of Sciences. 111:16532-16537
We have developed a screening platform for the isolation of genetic entities involved in metastatic reactivation. Retroviral libraries of cDNAs from fully metastatic breast-cancer cells or pooled microRNAs were transduced into breast-cancer cells tha
Autor:
Ho Sup Yoon, Vivekanandan Subramanian, Kwanghee Baek, Hong Ye, Baihong Li, Goutam Chakraborty, Yu Liang, Bo-Hwa Choi, Amaravadhi Harikishore
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828:1083-1093
MFG-E8 (also known as lactadherin), which is a secreted glycoprotein from a variety of cell types, possesses two EGF domains and tandem C domains with sequence homology to that of blood coagulation proteins factor V and factor VIII. MFG-E8 binds to p
Autor:
Muzaffar Akram, Filippo G. Giancotti, Hua Gao, Birgit Leitinger, Intissar Akalay, Surajit Sinha, Mayur Gadiya, Jian Hu, Edi Brogi, Zhanguo Zhang, Yaquan Gao, Goutam Chakraborty, Cizhong Jiang
Genetic screening identifies the atypical tetraspanin TM4SF1 as a strong mediator of metastatic reactivation of breast cancer. Intriguingly, TM4SF1 couples the collagen receptor tyrosine kinase DDR1 to the cortical adaptor syntenin 2 and, hence, to P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1ba715c74143c1ac9d6ee29f426c97
http://hdl.handle.net/10044/1/34241
http://hdl.handle.net/10044/1/34241
Autor:
Filippo G. Giancotti, Ai Ping Lee-Lim, Goutam Chakraborty, Qianxing Mo, Hua Gao, Alin Vonica, Ronglai Shen, Ali H. Brivanlou, Markus Decker, Edi Brogi
Publikováno v:
Cell. 150(4):764-779
SummaryThe mechanistic underpinnings of metastatic dormancy and reactivation are poorly understood. A gain-of-function cDNA screen reveals that Coco, a secreted antagonist of TGF-β ligands, induces dormant breast cancer cells to undergo reactivation
Autor:
Mitsuo Saito, Kostantin Dobrenis, Rui Fen Mao, Goutam Chakraborty, R. D. Shah, Dun-Sheng Yang, Mariko Saito, Asok Kumar
Publikováno v:
Journal of Neurochemistry. 121:649-661
GM2 ganglioside in the brain increased during ethanol-induced acute apoptotic neurodegeneration in 7-day-old mice. A small but a significant increase observed 2 h after ethanol exposure was followed by a marked increase around 24 h. Subcellular fract