Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Boyoun Park"'
Autor:
Yi Rang, Na, Daun, Jung, Michelle, Stakenborg, Hyeri, Jang, Gyo Jeong, Gu, Mi Reu, Jeong, Soo Youn, Suh, Hak Jae, Kim, Yoon Hey, Kwon, Tae Sik, Sung, Seung Bum, Ryoo, Kyu Joo, Park, Jong Pil, Im, Ji Yong, Park, Yun Sang, Lee, Heonjong, Han, Boyoun, Park, Sungwook, Lee, Daesik, Kim, Ho Su, Lee, Isabelle, Cleynen, Gianluca, Matteoli, Seung Hyeok, Seok
Publikováno v:
Gut. 70(12)
Dysfunctional resolution of intestinal inflammation and altered mucosal healing are essential features in the pathogenesis of inflammatory bowel disease (IBD). Intestinal macrophages are vital in the process of inflammation resolution, but the mechan
Publikováno v:
Molecular carcinogenesis. 58(8)
Cellular nucleic acid-binding protein (CNBP) is associated with cell proliferation, and its expression is elevated in human tumors, but the molecular mechanisms of CNBP in tumor cell biology have not been fully elucidated. In this study, we report th
Hyperproduction of IL-6 caused by aberrant TDP-43 overexpression in high-fat diet-induced obese mice
Publikováno v:
FEBS Letters. 589:1825-1831
Inclusion of Tat-activating regulatory DNA-binding protein-43 (TDP-43) due to hyperphosphorylation or hyperubiquitination is a cause of neurodegenerative disease. Cellular TDP-43 expression is tightly controlled through a negative feedback loop invol
Publikováno v:
Cellular immunology. 318
Toll-like receptor (TLR) signaling drives the innate immune response by activating nuclear factor-κB (NF-κB) and interferon regulatory factor (IRF). We have previously shown that STRAP interacts with TAK1 and IKKα along with NF-κB subunit p65, le
Autor:
J. Choi, Sungwook Lee, Sujin Kang, Taeyun A. Lee, Ji Eun Lee, Areum Park, Eunji Jang, Eun A. Ra, Boyoun Park, Hyunbin D. Huh, Eun Hye Lee
Publikováno v:
SCIENTIFIC REPORTS(6)
Scientific Reports
Scientific Reports
The WD40-repeat protein serine/threonine kinase receptor-associated protein (STRAP) is involved in the regulation of several biological processes, including cell proliferation and apoptosis, in response to various stresses. Here, we show that STRAP i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa07efae17e0e145689a550188b60cc
http://open-repository.kisti.re.kr/cube/handle/open_repository/485195.do
http://open-repository.kisti.re.kr/cube/handle/open_repository/485195.do
Autor:
Douglas T. Golenbock, Seija Lehnardt, Michael Hinz, F. Gregory Wulczyn, Oliver Peters, David Kaul, Boyoun Park, Jan Baumgart, Agnieszka Rybak, Eleonora Franzoni, Eckart Schott, Thorsten Trimbuch, Katja Derkow, Duong T. T. Nguyen, Frank L. Heppner, Christina Krüger, Hidde L. Ploegh, Robert Nitsch, Gina D. Eom, Rüdiger W. Veh, Roland E. Kälin, Olaf Ninnemann, Piet Habbel, Sabrina M. Lehmann, Karen Rosenberger
Publikováno v:
Nature Neuroscience. 15:827-835
Activation of innate immune receptors by host-derived factors exacerbates CNS damage, but the identity of these factors remains elusive. We uncovered an unconventional role for the microRNA let-7, a highly abundant regulator of gene expression in the
Autor:
Chih-Chi Andrew Hu, You-Me Kim, Markus R. Wenk, Stephanie K. Dougan, Boyoun Park, Guanghou Shui, Nicki Watson, Annette M McGehee, Elizabeth J. Klemm, Hidde L. Ploegh
Publikováno v:
The Journal of Immunology. 183:3690-3699
The accumulation of misfolded secreted IgM in the endoplasmic reticulum (ER) of X-box binding protein 1 (XBP-1)-deficient B cells has been held responsible for the inability of such cells to yield plasma cells, through the failure to mount a proper u
Autor:
Sang Jun Ha, Sujin Kang, Je-Hyun Yoon, Ju Seog Lee, Jae Hee Cheon, Areum Park, Boyoun Park, Taesun Park, Sungwook Lee, Hyojin Park, Eun Hye Lee, Seung Won Kim, Taeyun A. Lee
Publikováno v:
NATURE COMMUNICATIONS(6)
Processing of interleukin RNAs must be tightly controlled during the immune response. Here we report that a subnuclear body called the interleukin-6 and -10 splicing activating compartment (InSAC) is a nuclear site of cytokine RNA production and stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6900c2070fc28eed93d96e5ad9c117f
http://open-repository.kisti.re.kr/cube/handle/open_repository/480245.do
http://open-repository.kisti.re.kr/cube/handle/open_repository/480245.do
Publikováno v:
PMC
TLR signaling is essential to innate immunity against microbial invaders and must be tightly controlled. We have previously shown that TLR9 undergoes proteolytic cleavage processing by lysosomal proteases to generate two distinct fragments. The C-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0cba40874df86588096b246eeae7e02
https://orcid.org/0000-0002-1090-6071
https://orcid.org/0000-0002-1090-6071
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112754 (2014)
PLoS ONE
PLOS ONE(9): 11
PLoS ONE
PLOS ONE(9): 11
Cytokine production is essential for innate and adaptive immunity against microbial invaders and must be tightly controlled. Cytokine messenger RNA (mRNA) is in constant flux between the nucleus and the cytoplasm and in transcription, splicing, or de