Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bowen Gao"'
Autor:
Zhe Wang, Xinfeng Zhang, Lali K. Medina-Kauwe, Xiaojiang Cui, Tian-Yu Lee, Neil A. Bhowmick, Ying Zhang, Bingchen Han, Stephen L. Shiao, Xuemo Fan, Felix Alonso-Valenteen, Nan Deng, Bowen Gao, Armando E. Giuliano, Yali Xu, Sandrine Billet
Publikováno v:
Molecular Therapy. 30:672-687
Triple-negative breast cancer (TNBC) has a high propensity for organ-specific metastasis. However, the underlying mechanisms are not well understood. Here we show that the primary TNBC tumor-derived C-X-C motif chemokines 1/2/8 (CXCL1/2/8) stimulate
Autor:
Bowen Gao, Jian Huang, Changhao Chen, Jiang Zhu, Yue Zhao, Zhihua Li, Hanhao Zheng, Yuming Luo, Yuting Li, Le Ai, Hao Huang, Yao Kong
Publikováno v:
Molecular Therapy. 29:1838-1852
Lymphatic metastasis constitutes a leading cause of recurrence and mortality in bladder cancer. Accumulating evidence indicates that lymphangiogenesis is indispensable to trigger lymphatic metastasis. However, the specific mechanism is poorly underst
Autor:
Bowen Gao, Weidong Zhang, Yanfeng Wu, Huiyong Shen, Yangbai Sun, Fengfeng Li, Mengjun Ma, Sanhong Liu, Yuhang Jiang, Meng Chen
Publikováno v:
Theranostics
Rationale: Osteosarcoma (OS), the most common type of bone tumor, which seriously affects the patients' limb function and life quality. OS has a strong tendency of lung metastasis, and the five-year survival rate of patients with metastatic osteosarc
Autor:
Xiaojiang Cui, Bowen Gao, Yukun Cui, Xinfeng Zhang, Jiongyu Chen, Jijun Hao, Armando E. Giuliano, Bingchen Han
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Triple-negative breast cancer (TNBC) is associated with a high rate of early recurrence and distant metastasis, frequent development of therapeutic resistance, and a poor prognosis. There is a lack of targeted therapies for this aggressive subtype of
Autor:
Qizhi Liu, Stacey Chung, Michael M. Murata, Bingchen Han, Bowen Gao, Maoqi Zhang, Tian-Yu Lee, Evgeny Chirshev, Juli Unternaehrer, Hisashi Tanaka, Armando E. Giuliano, Yukun Cui, Xiaojiang Cui
Publikováno v:
International journal of biological sciences. 18(10)
Autor:
Yuming Luo, Keji Xie, Mingjie An, Yuting Li, Bowen Gao, Hanhao Zheng, Tianxin Lin, Min Yu, Yao Kong, Yiyao Ya, Jian Huang, Yan Lin, Wang He, Changhao Chen
Publikováno v:
Clinical and Translational Medicine
Clinical and Translational Medicine, Vol 11, Iss 7, Pp n/a-n/a (2021)
Clinical and Translational Medicine, Vol 11, Iss 7, Pp n/a-n/a (2021)
Background Patients with lymph node (LN) metastatic bladder cancer (BCa) present with extremely poor prognosis. BCa‐derived exosomes function as crucial bioactive cargo carriers to mediate the signal transduction in tumor microenvironment triggerin
Autor:
Jiang Zhu, Rufu Chen, Xiaofeng Guo, Hanhao Zheng, Yuting Li, Bowen Gao, Yao Kong, Yuming Luo, Zhihua Li, Changhao Chen
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 19, Iss 1, Pp 1-17 (2020)
Molecular Cancer, Vol 19, Iss 1, Pp 1-17 (2020)
Background Patients with lymph node (LN)-positive pancreatic ductal adenocarcinoma (PDAC) have extremely poor survival rates. Circular RNAs (circRNAs), a newly discovered type of endogenous noncoding RNAs, have been proposed to mediate the progressio
Autor:
Irina Voronov, Bowen Gao, Paul Corey, John H. Brumell, Luciene R. Carraro-Lacroix, Pascal N. Tyrrell, Andrew Wang, Celeste Owen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Mammalian target of rapamycin (mTOR) is activated by numerous stimuli, including amino acids and growth factors. This kinase is part of the mTOR complex 1 (mTORC1) which regulates cell proliferation, differentiation, and autophagy. Active mTORC1 is l
Autor:
Matthew P. Goetz, John A. Copland, Alvaro Moreno-Aspitia, Yan Lu, Donald W. Northfelt, Laura A. Marlow, Sarah A. McLaughlin, Xiaojia Tang, James L. Miller, Zhenkun Lou, Vera J. Suman, Bo Qin, Judy C. Boughey, Richard Gray, Amy Lynn Conners, Jia Yu, Anthony C. Schweitzer, Jason P. Sinnwell, Ann M. Moyer, Jason Hubbard, Daniel W. Visscher, Kevin J. Thompson, Krishna R. Kalari, Katie N. Hunt, Richard M. Weinshilboum, Liewei Wang, Katherine Minter-Dykhouse, Ping Yin, James N. Ingle, Bowen Gao
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 19, Iss 1, Pp 1-13 (2017)
Breast Cancer Research, Vol 19, Iss 1, Pp 1-13 (2017)
BackgroundPatient-derived xenografts (PDXs) are increasingly used in cancer research as a tool to inform cancer biology and drug response. Most available breast cancer PDXs have been generated in the metastatic setting. However, in the setting of ope
Autor:
Bingchen Han, Liting Jin, Yoshiko Nagaoka, Xiaojiang Cui, Makoto Katsumata, Ying Qu, Bowen Gao, Shikha Bose, Nan Deng, Armando E. Giuliano
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
The forkhead box transcription factor FOXC1 plays a critical role in embryogenesis and the development of many organs. Its mutations and high expression are associated with many human diseases including breast cancer. Although FOXC1 knockout mouse st