Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Li, Ying"'
Autor:
Li Ying, Zhen Li, Yang Shifa, Li Guiming, Renzhong Wan, Huang Zhongli, Chuanxi Sun, Ruirui Lian, Lin Shuqian, Liu Yueyue, Zhao Zengcheng, Bin Yin
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Keap1-Nrf2-ARE and heat shock proteins (Hsps) are important endogenous protection mechanisms initiated by heat stress to play a double protective role for cell adaptation and survival. H9C2 cells and 80 300-day-old specific pathogen-free chickens wer
Autor:
Jian Shen Qi, Thai Dinh, Timothy Tat, James Littrell, Ronald V. Swanson, Raul C. Camacho, Mary MacDonald, Ellen Chi, Lijuan Kang, Derek Steiner, Katharine D'Aquino, Jiali Li, Wenying Jian, Yue-Mei Zhang, James N. Leonard, Li Ying Wang, Yuanping Wang, Suzanne Edavettal, Michael J. Hunter, Wenyu Li, Case Martin A, Joseph Gunnet, Raymond J. Patch, Seohee You, Judy Connor, Wilson Edwards, Zhang Rui, James C. Lanter
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The long circulating half-life and inherently bivalent architecture of IgGs provide an ideal vehicle for presenting otherwise short-lived G-protein-coupled receptor agonists in a format that enables avidity-driven enhancement of potency. Here, we des
Autor:
Guo-xing Gan, Siyuan Tang, Jie Zhang, Li-Ying Shi, Bao-Ping Xie, Jin-Ping Li, Ying Zeng, Lu-juan Jia, Wei Liu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 117, Iss, Pp-(2019)
Oleanolic acid (OA) has recently become a research hotspot in the treatment of many human diseases, especially osteoporosis and arthritis. However, the mechanisms are not elucidated completely. We aimed to elucidate the target and the mechanism via w
Publikováno v:
European Journal of Medicinal Chemistry. 151:849-860
Xanthine oxidase, which catalyzes the oxidative reaction of hypoxanthine and xanthine into uric acid, is a key enzyme to the pathogenesis of hyperuricemia and gout. In this study, for the purpose of discovering novel xanthine oxidase (XO) inhibitors,
Autor:
Fan Shiyong, Zhong Bohua, Ai-Ping Zheng, You-Zhi Zhang, Zeng-liang Jin, Nuo-Min Li, Li Ying, Yuan Li, He Xinhua, Ting-Ting Zhang, Li Yunfeng, Rui Xue
Publikováno v:
Journal of Psychopharmacology. 31:377-386
Our previous study indicated that a chiral compound 071031B was a novel serotonin and noradrenaline reuptake inhibitor with superior antidepressant activity compared to duloxetine. The present study aimed to investigate chiral pharmacology difference
Autor:
Dongxiao Yang, Jun-Wei Wang, Sai-Qi Wang, Xiaoli Shi, Hong-Min Liu, Yu Ke, Li-Ying Ma, Cong Wang, Ran Wang, Hongge Shi, Liming Chang, Kairui Zhou
Publikováno v:
Oncotarget
// Sai-Qi Wang 1, * , Cong Wang 1, * , Li-Ming Chang 1 , Kai-Rui Zhou 1 , Jun-Wei Wang 1 , Yu Ke 1 , Dong-Xiao Yang 1 , Hong-Ge Shi 1 , Ran Wang 1 , Xiao-Li Shi 1 , Li-Ying Ma 1 , Hong-Min Liu 1 1 School of Pharmaceutical Sciences, Zhengzhou Universi
Publikováno v:
Experimental eye research. 189
Purpose To investigate the potential protective effect of novel G protein coupled estrogen receptor (GPER1) against the neurotoxicity induced by NMDA in the mouse retina. Methods We induce retinal ganglion cells (RGCs) toxic injury through intravitre
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Bombyx batryticatus is a known traditional Chinese medicine (TCM) utilized to treat convulsions, epilepsy, cough, asthma, headaches, and purpura in China for thousands of years. This study is aimed at investigating the antiepileptic effects of protei
Publikováno v:
International immunopharmacology. 70
Nonylphenol (NP) is a widely distributed, toxic endocrine-disrupting chemical exhibiting estrogenic activity. However, its effect on allergic rhinitis (AR) remains unclear. In this study, the effects of NP on a murine model of AR were investigated. M
Autor:
Xin-Hui Zhang, Yun-Peng Gong, Le-Min Jiao, Wen Zhao, Hong-Min Liu, Li-Ying Ma, Hui Qiao, Xin Zhang, Qi An, Jin-Ling Huo, Yang Feifei, Zhang-Xu He
Publikováno v:
European Journal of Medicinal Chemistry. 210:112970
To discover novel anticancer agents with potent and low toxicity, we designed and synthesized a range of new thiosemicarbazone-indole analogues based on lead compound 4 we reported previously. Most compounds displayed moderate to high anticancer acti