Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Golov A"'
Autor:
Vera Golimbet, Kaleda Vg, Arkadiy K. Golov, Margarita Alfimova, Lilia I. Abramova, Nikolay Kondratyev
Publikováno v:
Russian Journal of Genetics. 57:1092-1099
The study investigated methylation of each cytosine within a fragment of the YJEFN3 gene located at one of the index loci of schizophrenia risk with the aim to determine whether methylation of this fragment is associated with the level of cognitive d
Autor:
Vera Golimbet, Margarita Alfimova, Arkadiy K. Golov, D. Yu. Galaktionova, S. A. Golubev, Nikolay Kondratyev, T. V. Nasedkina
Publikováno v:
Neuroscience and Behavioral Physiology. 49:1061-1066
Objectives. To identify relationships between the rs7341475 polymorphism and methylation of the reelin gene on the one hand and the severity of schizophrenia symptomatology and the neuropsychological indicator – semantic verbal fluency (VF) – on
Publikováno v:
Russian Journal of Genetics. 55:232-237
The largest genome-wide association studies have identified schizophrenia and intelligence associated variants in the MIR137HG locus containing genes encoding microRNA-137 and microRNA-2682. In the present study, we investigated DNA methylation in th
Publikováno v:
Psychiatry Research. 272:380-386
Genetic variation may impact on local DNA methylation patterns. Therefore, information about allele-specific DNA methylation (ASM) within disease-related loci has been proposed to be useful for the interpretation of GWAS results. To explore mechanism
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Interrogating DNA methylation within schizophrenia risk loci holds promise to identify mechanisms by which genes influence the disease. Based on the hypothesis that allele specific methylation (ASM) of a single CpG, or perhaps CpH, might mediate or m
Publikováno v:
Молекулярная биология. 52:782-792
—There is a decrease in the expression of the reelin gene (RELN) in the brain of schizophrenia patients, which can underlie observed cognitive abnormalities. It is suggested that this decrease is caused by the hypermethylation of the RELN promoter.
Autor:
Alfimova, M. V., Kondratyev, N. V., Golov, A. K., Kaleda, V. G., Abramova, L. I., Golimbet, V. E.
Publikováno v:
Russian Journal of Genetics; Sep2021, Vol. 57 Issue 9, p1092-1099, 8p
Publikováno v:
Clinical Epigenetics
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-11 (2018)
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-11 (2018)
Background Methylation of DNA is associated with a variety of biological processes. With whole-genome studies of DNA methylation, it became possible to determine a set of genomic sites where DNA methylation is associated with a specific phenotype. A
Autor:
Arkadiy K. Golov, T. V. Nasedkina, Vera Golimbet, S. A. Golubev, Nikolay Kondratyev, Margarita Alfimova, D. Yu. Galaktionova
Publikováno v:
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 118(9)
To study the role of polymorphism rs7341475 and methylation of the reelin gene in symptoms of schizophrenia and semantic verbal fluency.Genotypes at the locus rs7341475 were identified in 556 patients with schizophrenic disorders. PANSS scores were o
Publikováno v:
Scientific Reports; 3/13/2020, Vol. 10 Issue 1, p1-12, 12p