Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Navedul Haque"'
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 23(6)
A new series of tetrasubstituted thiophene analogues (4a-4f, 5a-5f and 8a-8i) were designed incorporating the pharmacophoric features of COX-1 (as in fenamates), 5-LOX and the p38 MAP kinase inhibitors. The designed series was synthesized by nucleoph
Publikováno v:
Ethiopian Pharmaceutical Journal; Vol 24, No 1 (2006); 1-12
Fourteen novel tetrasubstituted thiophene esters (VIIIa-VIIIg) and the corresponding acid derivatives (IXa- IXg) were designed, synthesized, characterized and evaluated for their anti-inflammatory activity in carrageenin-induced rat hind paw oedema m