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pro vyhledávání: '"Wijitra Chumboatong"'
Autor:
Wijitra Chumboatong, Jiraporn Tocharus, Piyarat Govitrapong, Satchakorn Khamchai, Chainarong Tocharus
Publikováno v:
Neurotoxicity Research. 40:259-266
Cerebral ischemic stroke is one of the main causes of death and long-term disability worldwide. However, the mechanism is unclear, and treatments are limited. In this study, we aimed to investigate the anti-inflammatory effect of agomelatine in a per
Autor:
Wijitra Chumboatong, Chainarong Tocharus, Jiraporn Tocharus, Sarinthorn Thummayot, Piyarat Govitrapong, Jinatta Jittiwat
Publikováno v:
Neurochemistry international. 102
Agomelatine is an agonist of the melatonergic MT1/MT2 receptors and an antagonist of the serotonergic 5-HT receptors. Its actions mimic melatonin in antioxidative and anti-inflammation. However, the protective mechanism of agomelatine in ischemic/rep