Zobrazeno 1 - 10
of 113
pro vyhledávání: '"R. Scott Hawley"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 7, Pp 1959-1967 (2016)
Balancer chromosomes are multiply inverted chromosomes that suppress meiotic crossing over and prevent the recovery of crossover products. Balancers are commonly used in Drosophila melanogaster to maintain deleterious alleles and in stock constructio
Externí odkaz:
https://doaj.org/article/1f8248b1862749828ae6d297d5d621be
Autor:
R. Scott Hawley, Stacie E. Hughes
Publikováno v:
Trends in Genetics. 36:833-844
The synaptonemal complex (SC), a highly conserved structure built between homologous meiotic chromosomes, is required for crossover formation and ensuring proper chromosome segregation. In many organisms, SC components can also form alternative struc
Publikováno v:
Chromosoma
Experiments performed in different genetic backgrounds occasionally exhibit failure in experimental reproducibility. This is a serious issue in Drosophila where there are no standard control stocks. Here, we illustrate the importance of controlling g
Autor:
Cathleen M Lake, Rachel J Nielsen, Fengli Guo, Jay R Unruh, Brian D Slaughter, R Scott Hawley
Publikováno v:
eLife, Vol 4 (2015)
Meiotic recombination begins with the induction of programmed double-strand breaks (DSBs). In most organisms only a fraction of DSBs become crossovers. Here we report a novel meiotic gene, vilya, which encodes a protein with homology to Zip3-like pro
Externí odkaz:
https://doaj.org/article/374a93082f654501b793e89cf8a8a2d2
Autor:
Cathleen M. Lake, R. Scott Hawley
Publikováno v:
Current biology : CB. 31(5)
Cathleen Lake and Scott Hawley discuss the components, assembly and functional importance of the synaptonemal complex.
Autor:
R. Scott Hawley, Amanda M. Bonner
Publikováno v:
Molecular Biology and Evolution
Meiosis is a defining characteristic of eukaryotes, believed to have evolved only once, over one billion years ago. While the general progression of meiotic events is conserved across multiple diverse organisms, the specific pathways and proteins inv
Autor:
Stacie E. Hughes, R. Scott Hawley
Publikováno v:
Curr Biol
Interhomolog crossovers (COs) are a prerequisite for achieving accurate chromosome segregation during meiosis [1, 2]. COs are not randomly positioned, occurring at distinct genomic intervals during meiosis in all species examined [3, 4, 5, 6, 7, 8, 9
Autor:
Katherine Kretovich Billmyre, G. Matthew Heenan, R. Scott Hawley, Jay R. Unruh, Zulin Yu, Satomi Takeo, Emily R. Wesley, Cori K. Cahoon
The synaptonemal complex (SC) is a conserved meiotic structure that regulates the repair of double-strand breaks (DSBs) into crossovers or gene conversions. The removal of any central-region SC component, such as the Drosophila melanogaster transvers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9029ed0b9571d1dae8af8252cbfab4ef
https://europepmc.org/articles/PMC6815145/
https://europepmc.org/articles/PMC6815145/
The Molecular and Genetic Characterization of Second Chromosome Balancers in Drosophila melanogaster
Autor:
R. Scott Hawley, Angela L Miller, Vivienne Fang, Danny E. Miller, Kevin R. Cook, Elizabeth A Hemenway, Karen G. Hales
Publikováno v:
G3: Genes|Genomes|Genetics
Balancer chromosomes are multiply inverted and rearranged chromosomes used in Drosophila melanogaster for many tasks, such as maintaining mutant alleles in stock and complex stock construction. Balancers were created before molecular characterization
Publikováno v:
Genetics. 208:875-908
A century of genetic studies of the meiotic process in Drosophila melanogaster females has been greatly augmented by both modern molecular biology and major advances in cytology. These approaches, and the findings they have allowed, are the subject o