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pro vyhledávání: '"Laura M. Sipe"'
Autor:
Ajeeth K. Pingili, Jared C Clements, Joseph F. Pierre, Mehdi Chaib, Neena A John, Emily B. Korba, Mary C Lovely, Laura M. Sipe, Liza Makowski
Publikováno v:
Cancer Research. 81:PS17-29
Background: Obesity leads to a higher risk of cancer invasion, metastases, recurrence, mortality, and impaired therapeutic response through various mechanisms. One of these mechanisms is microenvironment dysfunction, where changes in immune cells, mi
Autor:
Weiping Chen, Laura M. Sipe, Richard L. Proia, Maria L. Allende, Galina Tuymetova, Kelsey L. Wilson-Henjum
Publikováno v:
Journal of Biological Chemistry. 288:18381-18391
Sphingosine 1-phosphate (S1P) is a bioactive lipid whose levels are tightly regulated by its synthesis and degradation. Intracellularly, S1P is dephosphorylated by the actions of two S1P-specific phosphatases, sphingosine-1-phosphate phosphatases 1 a