Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pranav Danthi"'
Autor:
Anthony J. Snyder, Pranav Danthi
Publikováno v:
Journal of Virology. 93
The environment represents a significant barrier to infection. Physical stressors (heat) or chemical agents (ethanol) can render virions noninfectious. As such, discrete proteins are necessary to stabilize the dual-layered structure of mammalian orth
Publikováno v:
Journal of Virology. 93
The mammalian orthoreovirus (reovirus) outer capsid is composed of 200 μ1-σ3 heterohexamers and a maximum of 12 σ1 trimers. During cell entry, σ3 is degraded by luminal or intracellular proteases to generate the infectious subviral particle (ISVP
Autor:
Anthony J. Snyder, Pranav Danthi
The environment represents a significant barrier to infection. Physical stressors (heat) or chemical agents (ethanol and sodium dodecyl sulfate) can render virions noninfectious. As such, discrete proteins are necessary to stabilize the dual layered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391bc4f92da658a9fdd1210635b8307d
The mammalian orthoreovirus (reovirus) outer capsid is composed of 200 μ1-σ3 heterohexamers and a maximum of 12 σ1 trimers. During cell entry, σ3 is degraded by luminal or intracellular proteases to generate a metastable intermediate, called infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a730607811917cc0add510199d1901
https://doi.org/10.1101/357343
https://doi.org/10.1101/357343
Publikováno v:
Journal of Virology. 86:3466-3473
Membrane penetration by reovirus requires successive formation of two cell entry intermediates, infectious subvirion particles (ISVPs) and ISVP*s. In vitro incubation of reovirus virions with high concentration of chymotrypsin (CHT) results in partia
Autor:
Joshua D. Doyle, Terence S. Dermody, Emily A. Kendall, Laura S. Ooms, Pranav Danthi, J. Denise Wetzel
Publikováno v:
Journal of Biological Chemistry. 287:8029-8038
Following attachment and internalization, mammalian reoviruses undergo intracellular proteolytic disassembly followed by viral penetration into the cytoplasm. The initiating event in reovirus disassembly is the cathepsin-mediated proteolytic degradat
Autor:
Barbara Sherry, Geoffrey H. Holm, Jennifer Zurney, Pranav Danthi, Simon Leveille, Terence S. Dermody, John Hiscott, Vanessa Tumilasci
Publikováno v:
The Journal of biological chemistry. 282(30)
During viral infection, cells initiate antiviral responses to contain replication and inhibit virus spread. One protective mechanism involves activation of transcription factors interferon regulatory factor-3 (IRF-3) and NF-kappaB, resulting in secre