Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
Ying Wang, Cynthia D. Guy, Cynthia A. Moylan, Anna Mae Diehl, Catherine F. Howe, Manal F. Abdelmalek, Ricardo Henao, Kara Wegermann
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 5, Iss 4, Pp 608-617 (2021)
Hepatology Communications, Vol 5, Iss 4, Pp 608-617 (2021)
Identifying patients at higher risk for poor outcomes from nonalcoholic fatty liver disease (NAFLD) remains challenging. Metabolomics, the comprehensive measurement of small molecules in biological samples, has the potential to reveal novel noninvasi
Autor:
Franklin G. Berger, Balaraman Kalyanaraman, Anna Mae Diehl, Varun Chandrashekaran, Jacek Ziolenka, Diptadip Dattaroy, Firas Alhasson, James A. Carson, Ratanesh Seth, Saurabh Chatterjee
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 8-19 (2017)
Redox Biology
Redox Biology
Recent clinical studies found a strong association of colonic inflammation and Inflammatory bowel disease (IBD)-like phenotype with NonAlcoholic Fatty liver Disease (NAFLD) yet the mechanisms remain unknown. The present study identifies high mobility
Autor:
Gregory A. Michelotti, Mark L. Jewell, Marzena Swiderska-Syn, Richard T. Premont, Anna Mae Diehl, Guanhua Xie, Wing-Kin Syn
Publikováno v:
Hepatology. 64:232-244
Introduction: Adult liver regeneration requires induction and suppression of proliferative activity in multiple types of liver cells. The mechanisms that orchestrate the global changes in gene expression that are required for proliferative activity t
Autor:
Xiao-Fan Wang, Bin Yang, Wenhao Qin, Anna Mae Diehl, Gregory A. Michelotti, Qi-Jing Li, Geoffrey J. Markowitz, Rui Chen, Jianhua Sui, Zheng Zhang, Jing Fu, Fu-Sheng Wang, Hongyang Wang, Pengyuan Yang
Publikováno v:
Cancer Research. 76:2394-2405
Chronic inflammation in liver tissue is an underlying cause of hepatocellular carcinoma. High levels of inflammatory cytokine IL18 in the circulation of patients with hepatocellular carcinoma correlates with poor prognosis. However, conflicting resul
Autor:
Ayako Suzuki, Cynthia D. Guy, Jagpal Singh Klair, Ju Dong Yang, Jeanne M. Clark, Katherine P. Yates, Anna Mae Diehl, Ryan M. Gill, Aynur Unalp-Arida, Manal F. Abdelmalek, Joel E. Lavine
Publikováno v:
Hepatology. 64:85-91
UNLABELLED Postmenopausal women with nonalcoholic steatohepatitis are at an increased risk of hepatic fibrosis compared with premenopausal women. Whether duration of estrogen deficiency in postmenopausal state dictates an individual's fibrosis risk r
Autor:
Steve S. Choi, Anna Mae Diehl
Consumption of alcohol is common in adults, and modest consumption has reported health benefits; however, chronic daily alcohol consumption above recommended limits is an important cause of chronic liver disease and cirrhosis. The amount and duration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c52372bf4b412069beda1bd191748a35
https://doi.org/10.1016/b978-0-323-47874-8.00008-0
https://doi.org/10.1016/b978-0-323-47874-8.00008-0
Autor:
Ann O. Scheimann, Emily R. Perito, Jean P. Molleston, Jeffrey B. Schwimmer, Katherine P. Yates, Veeral Ajmera, Nathan M. Bass, Karen F. Murray, David V. Glidden, Bradley E. Aouizerat, Ryan M. Gill, Anna Mae Diehl, Philip J. Rosenthal, Joel E. Lavine
Publikováno v:
Hepatology Communications, vol 1, iss 7
Hepatology Communications
Hepatology Communications
Author(s): Perito, Emily R; Ajmera, Veeral; Bass, Nathan M; Rosenthal, Philip; Lavine, Joel E; Schwimmer, Jeffrey B; Yates, Katherine P; Diehl, Anna Mae; Molleston, Jean P; Murray, Karen F; Scheimann, Ann; Gill, Ryan; Glidden, David; Aouizerat, Bradl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc138c4deb5cd509ef99545484dfd72
https://escholarship.org/uc/item/8cv9c55d
https://escholarship.org/uc/item/8cv9c55d
Autor:
Diptadip Dattaroy, Stephen Igwe, Suvarthi Das, Anna Mae Diehl, Daping Fan, Gregory A. Michelotti, Ratanesh Seth, Sahar Pourhoseini, Julie Basu Ray, Saurabh Chatterjee
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 352:77-89
Activation of M1 macrophages in nonalcoholic steatohepatitis (NASH) is produced by several external or endogenous factors: inflammatory stimuli, oxidative stress, and cytokines are known. However, any direct role of oxidative stress in causing M1 pol
Publikováno v:
Hepatology. 61:98-107
Hedgehog (Hh) ligand production by ballooned hepatocytes drives nonalcoholic steatohepatitis (NASH) progression in mice. The NIDDK-sponsored PIVENS trial (NCT00063622) showed that vitamin E (VitE) improved NASH. We investigated whether VitE treatment
Autor:
Anna Mae Diehl, Mariana Verdelho Machado, Marzena Swiderska-Syn, Wing-Kin Syn, Richard T. Premont, Gamze Karaca, Leandi Krüger, Guanhua Xie, Steve S. Choi, Gregory A. Michelotti
Publikováno v:
Gut. 63:1333-1344
Objective Smoothened (SMO), a coreceptor of the Hedgehog (Hh) pathway, promotes fibrogenic repair of chronic liver injury. We investigated the roles of SMO+ myofibroblast (MF) in liver regeneration by conditional deletion of SMO in α smooth muscle a