Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Ann-Kathrin Knöfel"'
Autor:
Tomoyuki Nakagiri, Fabio Ius, Ann-Kathrin Knöfel, Tobias Goecke, Patrick Zardo, Tobias Welte, Sabine Wrenger, Veronika Grau, Kokilavani Sivaraman, Axel Haverich, Sabina Janciauskiene
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
Respiratory Research
Respiratory Research
Background α1-Antitrypsin (AAT) is an acute phase glycoprotein, a multifunctional protein with proteinase inhibitory, anti-inflammatory and cytoprotective properties. Both preclinical and clinical experiences show that the therapy with plasma purifi
Autor:
K. Beushausen, Fabio Ius, Ann-Kathrin Knöfel, Jana Keil, Axel Haverich, N. Ledwoch, J. Kühne, Christine S. Falk, Lena Radomsky, Wiebke Sommer, Evgeny Chichelnitskiy, Gregor Warnecke, F Wandrer, Bettina Wiegmann, Sebastian V. Rojas
Publikováno v:
Cytokine. 149
Background Ischemia/reperfusion injury (IRI) is associated with inflammatory responses contributing to the development of primary graft dysfunction (PGD) and rejection. Here, we investigated the pathophysiology of IRI and the early phase after heart
Autor:
Marion Hewicker-Trautwein, Jawad Salman, Michael S. Balzer, Gregor Warnecke, Thierry Siemeni, Jeanette Pichler, Axel Haverich, Danny Jonigk, Klaus Höffler, Katharina Jansson, Reza Poyanmehr, Karolin S. Hacker, Jens Gottlieb, Jörg Frühauf, Martin Werner, Wiebke Sommer, Ann-Kathrin Knöfel, Murat Avsar
Publikováno v:
Transplant immunology. 65
We previously induced long-term allograft acceptance in an allogeneic lung transplantation (LTx) model in miniature swine using perioperative non-myeloablative irradiation (IRR) combined with infusion of donor specific alloantigen. In order to improv
Autor:
Gregor Warnecke, Ann-Kathrin Knöfel, Tomoyuki Nakagiri, L. Ahrens, A. Haverich, Danny Jonigk, K. Jannson, Nodir Madrahimov, S. Lienenklaus
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 66:S1-S110
Autor:
K.S. Hacker, Thierry Siemeni, Ann-Kathrin Knöfel, Tomoyuki Nakagiri, Jawad Salman, Fabio Ius, Axel Haverich
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:S307
Purpose Chronic lung allograft dysfunction (CLAD) is the most important complication after lung transplantation (LTx), which is classified bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS). Acute rejection (AR) is a hig
Autor:
L. Horn, Christine S. Falk, Gregor Warnecke, Danny Jonigk, K. Bläsing, Wiebke Sommer, Ann-Kathrin Knöfel, Igor Tudorache, Fabio Ius, Bettina Wiegmann, R. Bellmas Sanz, Axel Haverich, J. Kühne, A. Hitz
Publikováno v:
The Journal of Heart and Lung Transplantation. 39:S198
Purpose After lung transplantation (LuTx), a transient chimerism of donor cells exists in the blood of recipients due to the migration of lymphocytes from the transplanted lung into the periphery. We aimed to characterize the phenotype of donor CD8+
Autor:
Igor Tudorache, A. Haverich, Thierry Siemeni, Jawad Salman, Christine S. Falk, Murat Avsar, Fabio Ius, Gregor Warnecke, Reza Poyanmehr, Christian Kühn, Wiebke Sommer, Ann-Kathrin Knöfel
Publikováno v:
The Journal of Heart and Lung Transplantation. 38:S137-S138
Purpose Chronic lung allograft dysfunction (CLAD) is a severe complication of lung transplantation (LTX) limiting long term survival. Here, we studied correlations between CLAD after clinical LTX and leukocyte-mediated development of transplant arter
Autor:
Jawad Salman, Tomoyuki Nakagiri, Tobias Welte, Thierry Siemeni, Igor Tudorache, Wiebke Sommer, Ann-Kathrin Knöfel, Fabio Ius, Axel Haverich, Christian Kühn, Christine S. Falk, Gregor Warnecke
Publikováno v:
The Journal of Heart and Lung Transplantation. 38:S28-S29
Purpose Regulatory T cells (Treg) may counteract chronic lung allograft dysfunction (CLAD). In the present study, we analyzed Treg in peripheral blood at 3 weeks and at 3, 6, 12 and 24 months after lung transplantation and correlated the percentages
Autor:
Axel Haverich, Martin Strüber, Linda Pauksch, Martin Werner, K. Dreckmann, Wiebke Sommer, Gregor Warnecke, Ann-Kathrin Knöfel, Thierry Siemeni, Jens Gottlieb, Jörg Frühauf, Murat Avsar, Jawad Salman, Danny Jonigk, Katharina Jansson
Publikováno v:
Transplantation Direct, Vol 3, Iss 7, p e170 (2017)
Transplantation Direct
Transplantation Direct
Background. Preoperative low-dose whole-body irradiation (IRR) with 1.5 and 7 Gy thymic IRR of the recipient, combined with a perioperative donor splenocyte infusion lead to reliable donor specific peripheral tolerance in our allogeneic porcine lung
Autor:
Igor Tudorache, Axel Haverich, Jawad Salman, Tomoyuki Nakagiri, Wiebke Sommer, Ann-Kathrin Knöfel, Patrick Zardo, Fabio Ius, Gregor Warnecke, Murat Avsar, Thierry Siemeni
Publikováno v:
The Journal of Heart and Lung Transplantation. 38:S406
Purpose The outcome after lung transplantation is limited by chronic lung allograft dysfunction (CLAD), subclassified into bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS). RAS tends to an earlier, more severe and more