Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jan Tavernier"'
Autor:
Stefaan De Koker, Yann Bordat, Thomas Wueest, Sandra Van Lint, Dominiek Catteeuw, Gilles Uzé, José Van der Heyden, Annick Verhee, Alexander Van Parys, Anje Cauwels, Geneviève Garcin, Niko Kley, Jan Tavernier, Franciane Paul, Bart Vandekerckhove, Elke Rogge, Sarah Gerlo
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2018, 78 (2), pp.463-474. ⟨10.1158/0008-5472.CAN-17-1980⟩
Cancer Research, American Association for Cancer Research, 2018, 78 (2), pp.463-474. ⟨10.1158/0008-5472.CAN-17-1980⟩
An ideal generic cancer immunotherapy should mobilize the immune system to destroy tumor cells without harming healthy cells and remain active in case of recurrence. Furthermore, it should preferably not rely on tumor-specific surface markers, as the
Autor:
Jan Tavernier, Kenny Roose, Lien Van Hoecke, Alexander Van Parys, Xavier Saelens, Stefaan De Koker, Sandra Van Lint, Johan Grooten, Peter Vandenabeele
Publikováno v:
Cell Stress
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
NATURE COMMUNICATIONS
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
NATURE COMMUNICATIONS
Cancer immunotherapy can induce durable antitumor responses. However, many patients poorly respond to such therapies. Here we describe a generic antitumor therapy that is based on the intratumor delivery of mRNA that codes for the necroptosis executi
Autor:
Niek N. Sanders, Stefan Lienenklaus, Sandra Van Lint, Sunil A. David, Kim Deswarte, Zifu Zhong, Stefaan De Koker, João Paulo Portela Catani, Bruno G. De Geest, Lutz Nuhn, Jan Tavernier, Bart N. Lambrecht, Yupeng Li, Francis Combes
Publikováno v:
Advanced Materials, 30(45):1803397. Wiley-Blackwell
Localized therapeutic modalities that subvert the tumor microenvironment from immune-suppressive to pro-immunogenic can elicit systemic antitumor immune responses that induce regression of directly treated as well as nontreated distal tumors. A key t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab507c6cb8917c20af341c3cd1f794ae
https://pure.eur.nl/en/publications/cb3c0b78-b21c-4d06-9543-ca3e98288456
https://pure.eur.nl/en/publications/cb3c0b78-b21c-4d06-9543-ca3e98288456
Autor:
Nadja E. A. Drummen, Jan Tavernier, Juanita H. J. Vernooy, Guy Brusselle, Nele S. Pauwels, Robert-Jan van Suylen, Ken R. Bracke, Guy Joos, Emiel F.M. Wouters, Lennart Zabeau
Publikováno v:
Journal of Immunology, 184(12), 7169-7177. American Association of Immunologists
Leptin, a pleiotropic type I cytokine, was recently demonstrated to be expressed by resident lung cells in chronic obstructive pulmonary disease patients and asymptomatic smokers. To elucidate the functional role of leptin in the onset of chronic obs
Autor:
Claude Cuvelier, J Van der Heyden, Romain Pauwels, Guy Brusselle, Horst Bluethmann, Johan Kips, Jan Tavernier
Publikováno v:
Europe PubMed Central
To investigate the role of IL-4 in vivo in allergic asthma, we developed a murine model of allergen-induced airway inflammation. Repeated daily exposures of actively immunized C57BL/6 mice to aerosolized ovalbumin (OVA) induced a peribronchial inflam
Autor:
Annick Verhee, Frank Peelman, Tine Decruy, Liesbeth Faes, Dominiek Catteeuw, Lennart Zabeau, Dirk Elewaut, Jan Tavernier, Sylvie Seeuws
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2011, 441 (1), pp.425-434. ⟨10.1042/BJ20110438⟩
Biochemical Journal, Portland Press, 2011, 441 (1), pp.425-434. ⟨10.1042/BJ20110438⟩
The adipocyte-derived cytokine leptin acts as a metabolic switch, connecting the body's metabolism to high-energy consuming processes such as reproduction and immune responses. Accumulating evidence suggests that leptin plays a role in human patholog