Zobrazeno 1 - 10
of 800
pro vyhledávání: '"Preclinical research"'
Publikováno v:
Cold Spring Harbor perspectives in biology. 14(4)
Females have long been underrepresented in preclinical research and clinical drug trials. Directives by the U.S. National Institutes of Health have increased female participation in research protocols, although analysis of outcomes by sex remains inf
Publikováno v:
Инновационная медицина Кубани, Vol 0, Iss 1, Pp 47-55 (2021)
In this review, we discuss the advantages and disadvantages of the existing bone defect animal models and tissue engineering techniques applied in studying novel bone defect regenerative approaches. The paper suggests the requirements for an optimal
Autor:
William Flameng, Yoshinobu Onuma, Rodrigo Modolo, Patrick W. Serruys, Hadewych Van Hauwermeiren, Osama Ibrahim Ibrahim Soliman, Robbert J. de Winter, Wian van den Bergh, Rutao Wang, Hideyuki Kawashima, Martijn Cox, Mohammed El-Kurdi, Chun Chin Chang
Publikováno v:
EuroIntervention, 17(12), E1009-E1018. EuroPCR
Background: The Xeltis biorestorative transcatheter heart valve (BTHV) leaflets are made from an electrospun bioabsorbable supramolecular polycarbonate-urethane and are mounted on a self-expanding nitinol frame. The acute haemodynamic performance of
Autor:
M. Pilar Vinardell
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Psoriasis is a chronic inflammatory skin disease affecting about 2-3% of the worldwide population. More of the knowledge of psoriasis is due to the in vitro and in vivo models tried to reproduce the disease and to know the mechanisms of pathogenesis,
Autor:
Lukas Ernstbrunner, Reto Sutter, Manuel Waltenspül, Karl Wieser, Samy Bouaicha, Andreas Hecker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Scientific Reports
Scientific Reports
A fluoroscopically controlled anterior approach in supine position is often used for arthrocentesis of the shoulder, but can lead to a high rate of dry aspirations. The aim of this study was to compare the aspiration performance of rigid needles and
Autor:
Xuan Hao Tan, James C.H. Goh, Si Heng Sharon Tan, Chengchong Ai, James Hoi Po Hui, Yee Han Dave Lee
Publikováno v:
Journal of Orthopaedic Translation
Journal of Orthopaedic Translation, Vol 30, Iss, Pp 93-102 (2021)
Journal of Orthopaedic Translation, Vol 30, Iss, Pp 93-102 (2021)
The treatment of osteochondral defects (OCD) remains challenging. Among currently available surgical treatments for OCDs, scaffold-based treatments are promising to regenerate the osteochondral unit. However, there is still no consensus regarding the
Autor:
Keren Powell, Raj K. Narayan, Ping Wang, Anup N. Sonti, Weng Lang Yang, Mohini Doobay, Kevin A. Shah, Timothy G White, Lance B Becker, Wayne W. Chaung, Yi Chen Wu, Chunyan Li
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Traumatic peri-contusional penumbra represents crucial targets for therapeutic interventions after traumatic brain injury (TBI). Current resuscitative approaches may not adequately alleviate impaired cerebral microcirculation and, hence, compromise o
Publikováno v:
Journal Biomed. 17:84-89
An experimental model of direct acute lung injury was developed by intratracheal administration of lipopolysaccharide from Salmonella enterica (LD50 = 20 mg/kg). The dynamics of animal lethality, body weight, temperature and the severity of pathomorp
Autor:
Emile E. Voest, Vivien Veninga
Publikováno v:
Cancer Cell. 39:1190-1201
Summary Tumor organoids have been proposed as a model system for precision medicine. The ability of tumor organoids to retain characteristics of the original tumor makes them unique for cancer research on an individual patient level. Hence, the idea
Publikováno v:
International Journal of Hyperthermia, Vol 38, Iss 2, Pp 81-88 (2021)
High Intensity Focused Ultrasound (HIFU) capably bridges the disciplines of surgery, oncology and biomedical engineering science. It provides the precision associated with a surgical tool whilst remaining a truly non-invasive technique. Oxford has be