Zobrazeno 21 - 30
of 51
pro vyhledávání: '"Normanno N"'
Autor:
Filippo de Marinis, Alessandra Sacco, Rita Chiari, Giovanna Finocchiaro, Nicola Normanno, Federico Cappuzzo, Laura Giannetta, Ciro Battiloro, Raffaella Pasquale, Alessandro Morabito, Libero Ciuffreda, Marcello Tiseo, Maria Carmela Piccirillo, Roberta Buosi, Paolo Bidoli, Luisa Foltran, Riziero Esposito Abate, Gianpiero Fasola, G. Romano, Antonio Frassoldati
Publikováno v:
Cancers
Volume 11
Issue 10
Cancers, Vol 11, Iss 10, p 1431 (2019)
Volume 11
Issue 10
Cancers, Vol 11, Iss 10, p 1431 (2019)
The ICARUS trial is a phase II, open label, multicenter, single arm study conducted to investigate the efficacy, safety, and tolerability of a rechallenge treatment with the first-generation tyrosine kinase inhibitor (TKI) gefitinib in advanced non-s
Autor:
Silvana Leo, A. Rinaldi, Francesco Giuliani, Salvatore Pisconti, R. Esposito Abate, Alessia Iannaccone, Fortunato Ciardiello, Matilde Lambiase, Anna Maria Rachiglio, Evaristo Maiello, E. Martinelli, Nicola Normanno, M. Biglietto, Laura Forgione, Teresa Troiani, Tiziana Latiano, Roberto Bordonaro, Claudia Cardone, D. Rizzi, Alessandra Sacco
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 29(1)
Background Liquid biopsy is an alternative to tissue for RAS testing in metastatic colorectal carcinoma (mCRC) patients. Little information is available on the predictive role of liquid biopsy RAS testing in patients treated with first-line anti-EGFR
Autor:
Andrea Onetti Muda, Guido Giordano, Gianni Simone, Pietro Micheli, C. Barone, Giacomo Cartenì, Fabiana Tatangelo, Laura Longhitano, Vincenzo Rosario Iaffaioli, Alessandra Cassano, M. Biglietto, Anna Nappi, Sabrina Rossi, A.R. Bordonaro, A. Rinaldi, Francesco Sponziello, G. Modoni, GabrieleDi Maggio, Matilde Lambiase, Oscar Nappi, Claudia Cardone, Antonella Marino, Mirko Montrone, Sandro Barni, Michele Orditura, Antonio Febbraro, Paolo Graziano, Saverio Cinieri, Guglielmo Nasti, Fortunato Ciardiello, Evaristo Maiello, D. Rizzi, Vincenzo Sforza, Stefano Cordio, F. De Vita, Erika Martinelli, S. Romito, Vincenzo Montesarchio, Giuseppe Tonini, Annamaria Sebastio, Salvatore Pisconti, Nicola Normanno, Tiziana Guarino, Giuseppe Colucci, Francesco Giuliani, Anna Maria Rachiglio, Gerardo Botti, Nicoletta Chicchinelli, Tiziana Latiano, Teresa Troiani, Vito Lorusso, Michele Aieta, Silvana Leo, Giuseppe Grimaldi, Eugenio Tommaselli, Luigi Leo, Cinzia Chiarazzo, Mario Manusia
Publikováno v:
ESMO Open
In the cetuximab after progression in KRAS wild-type colorectal cancer patients (CAPRI) trial patients with metastatic colorectal cancer (mCRC) received 5-fluorouracil, folinic acid and irinotecan (FOLFIRI) and cetuximab in first line followed by 5-F
Autor:
Francesco Perrone, Simona Bevilacqua, Agnese Montanino, Simona Signoriello, Cesare Gridelli, Ciro Gallo, Massimo Di Maio, Antonio Rossi, Antonella De Luca, Gaetano Rocco, Raffaele Costanzo, Nicola Normanno, Alessandro Morabito
Publikováno v:
Lung Cancer. 85:314-319
Objectives Circulating tumor cells (CTCs) have been hypothesized to be a prognostic factor in small-cell lung cancer (SCLC), and different cutoffs have been proposed to identify patients at high risk. We assessed the prognostic value of CTCs in patie
Autor:
Elisabeth Dequeker, Silke Sterck, Hans Kreipe, Antonio Marchetti, Fiona H Blackhall, Marjolijn J L Ligtenberg, Outi Kämäräinen, Elke Boone, Zandra C. Deans, Miquel Taron, Ian A. Cree, Nicola Normanno, Sabine Tejpar, Frank J.M. Opdam, Albert G. Siebers, Etienne Rouleau, Peter M. van de Ven, Wim Timens, Anders Edsjö, Gerardo Botti, Fortunato Ciardiello, Patricia J. T. A. Groenen, Ilhan Celik, Simon Patton, Fátima Carneiro, Erik Thunnissen, Carmine Pinto, J. Han van Krieken, Ed Schuuring, Samuel S. Murray, Scott D. Patterson
Publikováno v:
Virchows Archiv, 462(1), 27-37. Springer Verlag
van Krieken, J H, Normanno, N, Blackhall, F, Boone, E, Botti, G, Carneiro, F, Celik, I, Ciardiello, F, Cree, I A, Deans, Z C, Edsjo, A, Groenen, P J T A, Kamarainen, O, Kreipe, H H, Ligtenberg, M J L, Marchetti, A, Murray, S, Opdam, F J M, Patterson, S D, Patton, S, Pinto, C, Rouleau, E, Schuuring, E, Sterck, S, Taron, M, Tejpar, S, Timens, W, Thunnissen, E, van de Ven, P M, Siebers, A G & Dequeker, E 2013, ' Guideline on the requirements of external quality assessment programs in molecular pathology ', Virchows Archiv, vol. 462, no. 1, pp. 27-37 . https://doi.org/10.1007/s00428-012-1354-4
Virchows Archiv, 462, 1, pp. 27-37
Virchows Archiv, 462, 27-37
van Krieken, J H, Normanno, N, Blackhall, F, Boone, E, Botti, G, Carneiro, F, Celik, I, Ciardiello, F, Cree, I A, Deans, Z C, Edsjo, A, Groenen, P J T A, Kamarainen, O, Kreipe, H H, Ligtenberg, M J L, Marchetti, A, Murray, S, Opdam, F J M, Patterson, S D, Patton, S, Pinto, C, Rouleau, E, Schuuring, E, Sterck, S, Taron, M, Tejpar, S, Timens, W, Thunnissen, E, van de Ven, P M, Siebers, A G & Dequeker, E 2013, ' Guideline on the requirements of external quality assessment programs in molecular pathology ', Virchows Archiv, vol. 462, no. 1, pp. 27-37 . https://doi.org/10.1007/s00428-012-1354-4
Virchows Archiv, 462, 1, pp. 27-37
Virchows Archiv, 462, 27-37
Contains fulltext : 118506.pdf (Publisher’s version ) (Closed access) Molecular pathology is an integral part of daily diagnostic pathology and used for classification of tumors, for prediction of prognosis and response to therapy, and to support t
Autor:
Giovanna Finocchiaro, Filippo de Marinis, Marcello Tiseo, Giulio Cerea, Alessandro Del Conte, Laura Giannetta, Maria Rita Migliorino, Rita Chiari, Marco Angelo Burgio, Francesca Mazzoni, Agnese Montanino, Alessandro Morabito, Federico Cappuzzo, Nicola Normanno, Roberta Buosi, Paolo Bidoli, Diego Cortinovis, Luisa Foltran, Silvia Ferrari
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 99
Objectives Although patients with advanced non-small cell lung cancer (NSCLC) and an activating epidermal growth factor receptor (EGFR) mutation benefit from the use of EGFR-tyrosine kinase inhibitors (TKI), most of them progress within 12 months fro
Autor:
R. Labianca, Fortunato Ciardiello, J.-Y. Douillard, Alfredo Falcone, André D'Hoore, C.-H. Köhne, Aziz Zaanan, George Pentheroudakis, Dan Aderka, Nicola Normanno, Takayuki Yoshino, Per Pfeiffer, H.-J. Schmoll, Al B. Benson, J.H.J.M. van Krieken, René Adam, Demetris Papamichael, Paulo M. Hoff, Jens Ricke, R. Salazar, György Bodoky, Harpreet Wasan, Josep Tabernero, Timothy J. Price, Dirk Arnold, Michel Ducreux, Alberto Sobrero, Thomas Gruenberger, Brigette B.Y. Ma, Axel Grothey, E. Aranda Aguilar, E. Van Cutsem, Karin Haustermans, Volker Heinemann, Pia Österlund, Kei Muro, Arnaud Roth, Eduardo Díaz-Rubio, Pierre Laurent-Puig, Andrés Cervantes, Alberto Bardelli, Wim J.G. Oyen, Julien Taieb, C.J.A. Punt, Sabine Tejpar, Tim Maughan, Werner Scheithauer
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Annals of Oncology, 27, 1386-422
Van Cutsem, E, Cervantes, A, Adam, R, Sobrero, A, Van Krieken, J H, Aderka, D, Aranda Aguilar, E, Bardelli, A, Benson, A, Bodoky, G, Ciardiello, F, D'Hoore, A, Diaz-Rubio, E, Douillard, J-Y, Ducreux, M, Falcone, A, Grothey, A, Gruenberger, T, Haustermans, K, Heinemann, V, Hoff, P, Köhne, C-H, Labianca, R, Laurent-Puig, P, Ma, B, Maughan, T, Muro, K, Normanno, N, Österlund, P, Oyen, W J G, Papamichael, D, Pentheroudakis, G, Pfeiffer, P, Price, T J, Punt, C, Ricke, J, Roth, A, Salazar, R, Scheithauer, W, Schmoll, H J, Tabernero, J, Taïeb, J, Tejpar, S, Wasan, H, Yoshino, T, Zaanan, A & Arnold, D 2016, ' ESMO consensus guidelines for the management of patients with metastatic colorectal cancer ', Annals of Oncology, vol. 27, no. 8, pp. 1386-1422 . https://doi.org/10.1093/annonc/mdw235
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Annals of Oncology, 27, 8, pp. 1386-422
Annals of oncology, 27(8), 1386-1422. Oxford University Press
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Annals of Oncology, 27, 1386-422
Van Cutsem, E, Cervantes, A, Adam, R, Sobrero, A, Van Krieken, J H, Aderka, D, Aranda Aguilar, E, Bardelli, A, Benson, A, Bodoky, G, Ciardiello, F, D'Hoore, A, Diaz-Rubio, E, Douillard, J-Y, Ducreux, M, Falcone, A, Grothey, A, Gruenberger, T, Haustermans, K, Heinemann, V, Hoff, P, Köhne, C-H, Labianca, R, Laurent-Puig, P, Ma, B, Maughan, T, Muro, K, Normanno, N, Österlund, P, Oyen, W J G, Papamichael, D, Pentheroudakis, G, Pfeiffer, P, Price, T J, Punt, C, Ricke, J, Roth, A, Salazar, R, Scheithauer, W, Schmoll, H J, Tabernero, J, Taïeb, J, Tejpar, S, Wasan, H, Yoshino, T, Zaanan, A & Arnold, D 2016, ' ESMO consensus guidelines for the management of patients with metastatic colorectal cancer ', Annals of Oncology, vol. 27, no. 8, pp. 1386-1422 . https://doi.org/10.1093/annonc/mdw235
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Annals of Oncology, 27, 8, pp. 1386-422
Annals of oncology, 27(8), 1386-1422. Oxford University Press
Contains fulltext : 165965.pdf (Publisher’s version ) (Closed access) Colorectal cancer (CRC) is one of the most common malignancies in Western countries. Over the last 20 years, and the last decade in particular, the clinical outcome for patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ccf2b801d4b95d9bd0bb5c50736ce1
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=3106
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=3106
Autor:
Francesco Sponziello, Saverio Cinieri, Giuseppe Grimaldi, Alessandra Cassano, M. Biglietto, Pietro Micheli, Gianni Simone, C. Barone, Fabiana Tatangelo, Antonella Marino, Giacomo Cartenì, Guglielmo Nasti, D. Rizzi, Antonio Febbraro, Cinzia Chiarazzo, Mario Manusia, Vito Lorusso, Fortunato Ciardiello, A.R. Bordonaro, S. Romito, Sabrina Rossi, Teresa Troiani, F. De Vita, Eugenio Tommaselli, Giuseppe Colucci, Andrea Onetti Muda, Guido Giordano, Luigi Leo, G. Modoni, Annamaria Sebastio, Sandro Barni, Francesco Giuliani, Paolo Graziano, M. Rachiglio, Michele Aieta, Evaristo Maiello, Enrica Martinelli, Mirko Montrone, Silvana Leo, Tiziana Latiano, Stefano Cordio, Laura Longhitano, Vincenzo Rosario Iaffaioli, Vincenzo Montesarchio, Nicola Normanno, Anna Nappi, Matilde Lambiase, Gerardo Botti, Gabriele Di Maggio, Giuseppe Tonini, Nicoletta Chicchinelli, Oscar Nappi, Claudia Cardone, Michele Orditura, A. Rinaldi, Salvatore Pisconti, Tiziana Guarino
Background Cetuximab plus chemotherapy is a first-line treatment option in metastatic KRAS and NRAS wild-type colorectal cancer (CRC) patients. No data are currently available on continuing anti-epidermal growth factor receptor (EGFR) therapy beyond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343fea2703fb6409297f48937f6f6bde
http://hdl.handle.net/11591/354385
http://hdl.handle.net/11591/354385
Autor:
Giuseppe Perrone, Mario Manusia, Erika Martinelli, Eugenio Tommaselli, Salvatore Pisconti, A. Perrino, M. Biglietto, Giuseppe Colucci, A. Cardarelli, A. Onetti Muda, Francesco Giuliani, Guido Rindi, Guglielmo Nasti, D. Rizzi, Anna Maria Rachiglio, Saverio Cinieri, Evaristo Maiello, Antonio Febbraro, Fortunato Ciardiello, Gianni Simone, Giacomo Cartenì, E. Montesarchio, Matilde Lambiase, Fabiana Tatangelo, Teresa Troiani, Nicola Normanno, G. Botti, Daniela Cabibi, A. Rinaldi, Alessia Iannaccone, Pietro Micheli, C. Barone, Oscar Nappi, Antonio Russo, Cristin Roma, Roberto Bordonaro, Claudia Esposito, Annamaria Sebastio, Francesca Fenizia, Paolo Graziano, S. Romito, Giuseppe Tonini, Pantaleo Bufo, Tiziana Latiano, Nicoletta Chicchinelli, P. Giaccone, M. Criscuolo
Background: Evidence suggests that metastatic colorectal carcinoma (mCRC) has a high level of intratumor heterogeneity. We carried out a quantitative assessment of tumor heterogeneity for KRAS, NRAS, BRAF and PIK3CA mutations, in order to assess pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00a8ef70d693dea7a745c8bef2ef289
http://hdl.handle.net/10447/295526
http://hdl.handle.net/10447/295526
Autor:
Barone, C., Giuliante, F., Adam, R., Pinto, C., Garufi, C., Folprecht, G., Falcone, Alfredo, Nuzzo, G., Van Cutsem, E., Ciardiello, F., Capussotti, L., Poston, G.
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e85897 (2014)
PLoS ONE, Vol 9, Iss 1, p e85897 (2014)
KRAS testing is relevant for the choice of the most appropriate first-line therapy of metastatic colorectal cancer (CRC). Strategies for preventing unequal access to the test should be implemented, but their relevance in the practice is related to ec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e56049119f186680599d34390986ed
http://hdl.handle.net/10281/184952
http://hdl.handle.net/10281/184952