Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nabendu Pore"'
Autor:
Diana Gibson, Andrew Spencer, Magdalini Migkou, Sikander Ailawadhi, Jeremy T. Larsen, Meletios A. Dimopoulos, Shaji Kumar, Marna Williams, Fujun Wang, Ioannis Kagiampakis, Farzana Walcott, Jeffrey A. Zonder, Lily Cheng, Nabendu Pore, Yu Jiang, Krista Kinneer, Shreerang Sirdesai, Manisha Bhutani, Andrew Yee, Anna Kalff
Publikováno v:
Blood. 136:26-27
Background: B-cell maturation antigen (BCMA) is widely expressed on normal plasma cells and malignant plasma cells in multiple myeloma (MM). MEDI2228 is an antibody-drug conjugate (ADC) that targets the extracellular domain of human BCMA with prefere
Autor:
George J. Cerniglia, Anjali K. Gupta, Stephen M. Hahn, Nabendu Pore, Eric J. Bernhard, Cameron J. Koch, Zibin Jiang, Sydney M. Evans, Amit Maity
Publikováno v:
Cancer Research. 66:9252-9259
The phosphatidylinositol 3-kinase (PI3K)/Akt pathway can increase vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1α (HIF-1α) expression. We examined the effect of nelfinavir, an HIV protease inhibitor that inhibits Akt signa
Autor:
Rosemarie Mick, William M. F. Lee, Nabendu Pore, Xiaoman Xing, Turgut Durduran, George J. Cerniglia, Amit M. Maity, Jeff H. Tsai, Harry Quon, Susan M. Schultz, Regine Choe, Cameron J. Koch, Stephen M. Hahn, Chandra M. Sehgal, Sydney M. Evans, Arjun G. Yodh
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6539 (2009)
PLoS ONE
PLoS ONE
Background: Epidermal growth factor receptor (EGFR) inhibitors have shown only modest clinical activity when used as single agents to treat cancers. They decrease tumor cell expression of hypoxia-inducible factor 1-a (HIF-1a) and vascular endothelial
Autor:
Brandon W. Higgs, Roger Wongjung Liu, Sanjoo Jalla, Robert Hollingsworrth, Emil Michelotti, Aldo Scarpa, Nabendu Pore, Claudio Sorio, David A. Tice
Publikováno v:
Cancer Research. 75:1109-1109
Re-programming of energy metabolism is one of the emerging hallmarks of cancer. Upregulation of energy metabolism pathways fuels cell growth and division, a key characteristic of neoplastic disease, and can lead to dependency on specific metabolic pa
Autor:
George J. Cerniglia, Jeff H. Tsai, Cameron J. Koch, A. Maity, Sydney M. Evans, Nabendu Pore, Chandra M. Sehgal, William M. F. Lee
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 72:S62
Purpose/Objective(s): A recently published randomized study showed that combining an EGFR inhibitor with radiation increases survival and local control in patients with locally advanced head and neck cancer. We were interested in understanding the ef