Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lucia Knopfová"'
Autor:
Petr Beneš, Jiří Jarkovský, Jana Katolická, Ivan Čapov, Jan Šmarda, Petr Vlček, Tichý M, Markéta Hermanová, Lucia Knopfová
Publikováno v:
Journal of Cancer
Colorectal cancer (CRC) represents a serious challenge for oncologists due to high incidence and large heterogeneity. Prognostic factors are needed to stratify patients according to risk of disease progression. In this study, we report that high expr
Overexpression of c-Myb is associated with suppression of distant metastases in colorectal carcinoma
Autor:
Lenka Veverková, Jiří Jarkovský, Ivan Čapov, Petr Beneš, Jana Katolická, Jan Šmarda, Markéta Hermanová, Lucie Pekarčíková, Petr Vlček, Tichý M, Lucia Knopfová
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
The MYB gene codes for the c-Myb transcription factor maintaining proliferation of colon epithelial progenitors, thus controlling colon development and homeostasis. This gene is overexpressed in early phases of colorectal cancer (CRC) tumorigenesis.
Autor:
Kateřina Kaňková, Katarína Chalásová, Lucia Knopfová, Josef Tomandl, Lukáš Pácal, Jitka Řehořová, Marie Tomandlová, Anna Pleskačová
Publikováno v:
Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 126(4)
Aim Pentose phosphate pathway (PPP) with key enzyme transketolase (TKT), represents a potentially ‘protective’ mechanism in hyperglycaemia. Diabetic kidney disease (DKD), a common complication of both type 1 and type 2 diabetes associated with si
Autor:
Vojtech Adam, Petr Babula, Monika Holubová, Martina Raudenská, Markéta Sztalmachová, Michal Masarik, Jaromír Gumulec, Jan Balvan, Hana Polanska, René Kizek, Lucia Knopfová, Kristyna Hudcova
Publikováno v:
International Journal of Oncology. 46:1810-1818
Breast cancer patients negative for the nuclear oestrogen receptor α have a particularly poor prognosis. Therefore, the 4T1 cell line (considered as a triple-negative model) was chosen to induce malignancy in mice. The aim of the present study was t
Autor:
Lucia Knopfová, Vlasta Lungová, Eva Matalová, Jan Šmarda, Marcela Buchtová, Eva Janečková, Abigail S. Tucker
Publikováno v:
European Journal of Oral Sciences. 120:495-504
The MYB family of transcription activators has been associated with a high proliferation rate and an undifferentiated state of cells in a number of tissues. Recently emerging data suggest that these molecules may also play a role in differentiation.
Autor:
Veronika Oralova, Marcela Buchtová, Eva Matalová, Michael Killinger, Jan Šmarda, Lucia Knopfová
Publikováno v:
Calcified tissue international. 100(3)
The transcription factor c-MYB is a well-known marker of undifferentiated cells such as haematopoietic cell precursors, but recently it has also been observed in differentiated cells that produce hard tissues. Our previous findings showed the presenc
Publikováno v:
European Journal of Cancer Supplements. 8:194
The aim of this study was to assess the role of the c-Myb protein in control of invasivity of breast cancer cells. MDA-MB-231 breast cancer cells were transfected with the c-Myb coding cDNA to prepare MDA-MB-231MYBup derivatives. MDA-MB-231MYBup cell