Zobrazeno 101 - 110
of 180
pro vyhledávání: '"Hans M.G. Princen"'
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 21(11)
Fibrates are hypolipidemic drugs that affect the expression of genes involved in lipid metabolism by activating peroxisome proliferator-activated receptors (PPARs). Fibrate treatment causes adverse changes in biliary lipid composition and decreases b
Autor:
J.Marleen L. De Vree, Folkert Kuipers, Nynke R. Koopen, Rick Havinga, Ronald P.J. Oude Elferink, Peter J. Voshol, Hans M.G. Princen, Albert K. Groen
Publikováno v:
Journal of Hepatology, 34(2), 202-209. ELSEVIER SCIENCE BV
Journal of Hepatology, 2, 34, 202-209
University of Groningen
Journal of hepatology, 34(2), 202-209. Elsevier
Journal of Hepatology, 2, 34, 202-209
University of Groningen
Journal of hepatology, 34(2), 202-209. Elsevier
Background/Aims: Mdr2 P-glycoprotein deficiency in mice (Mdr2(-/-)) leads to formation of cholesterol/cholesterol-depleted bile and reduced plasma HDL cholesterol. We addressed the questions: (1) does HDL in Mdr2(-/-) mice normalize upon phospholipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c962137ec5802a38c5179c47969cb8
https://research.rug.nl/en/publications/6b88047e-4876-4afb-8833-c10f8e37925e
https://research.rug.nl/en/publications/6b88047e-4876-4afb-8833-c10f8e37925e
Autor:
J.W. Jukema, H. van der Boom, L.M. Havekes, E.C.M. de Wit, W. van Duyvenvoorde, E.H. Offerman, Dianne J.M. Delsing, A. van der Laarse, Hans M.G. Princen, Marion J.J. Gijbels
Publikováno v:
Circulation, 13, 103, 1778-1786
Circulation, 103(13), 1778-1786. Lippincott Williams and Wilkins
Scopus-Elsevier
Circulation, 103(13), 1778-1786. Lippincott Williams and Wilkins
Scopus-Elsevier
Background —The present study investigated whether the ACAT inhibitor avasimibe can reduce atherogenesis independently of its cholesterol-lowering effect in ApoE*3-Leiden mice. Methods and Results —Two groups of 15 female ApoE*3-Leiden mice were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3bde6ac72f3e1f4ad9e3d2dfef3dac
http://resolver.tudelft.nl/uuid:85b365bd-e856-4f9d-aa3d-73b1481a4448
http://resolver.tudelft.nl/uuid:85b365bd-e856-4f9d-aa3d-73b1481a4448
Autor:
A.F.M. Kardinaal, Diederick E. Grobbee, Hans M.G. Princen, G. van Poppel, L.P.L. van de Vijver, C. Weber
Publikováno v:
Free radical research. 30(3)
Coenzyme Q10 (CoQ10) is an important mitochondrial electron transfer component and has been postulated to function as a powerful antioxidant protecting LDL from oxidative damage. It could thus reduce the risk of cardiovascular disease. Thus far, bene
Autor:
Hans M.G. Princen, Martine Deckers, Victor W.M. van Hinsbergh, Paul H.A. Quax, M.R. de Vries, J.H.P. Lardenoye, D. J. M. Delsing, J.H. van Bockel, Louis M. Havekes
Publikováno v:
Lardenoye, J H, Delsing, D J, de Vries, M R, Deckers, M M, Princen, H M G, Havekes, L M, van Hinsbergh, V W M, van Bockel, J H & Quax, P H A 2000, ' Accelerated atherosclerosis by placement of a perivascular cuff and a cholesterol-rich diet in ApoE*3 Leiden transgenic mice. ', Circulation Research, vol. 87, no. 3, pp. 248-53 . https://doi.org/10.1161/01.res.87.3.248
Scopus-Elsevier
Circulation Research, 87(3), 248-53. Lippincott Williams and Wilkins
Europe PubMed Central
Circulation Research, 3, 87, 248-253
Scopus-Elsevier
Circulation Research, 87(3), 248-53. Lippincott Williams and Wilkins
Europe PubMed Central
Circulation Research, 3, 87, 248-253
Intimal hyperplasia after vascular injury is usually studied in animal models with healthy, normocholesterolemic animals. Here, we assess the effect of diet-induced hypercholesterolemia on the induction of intimal hyperplasia in ApoE*,3Leiden mice. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec54103c9837def3a078ae258643897
https://research.vumc.nl/en/publications/02e4d575-4ef2-42c0-81ec-5b6a9c0fa9c4
https://research.vumc.nl/en/publications/02e4d575-4ef2-42c0-81ec-5b6a9c0fa9c4
Autor:
Mettine H.A. Bos, Hans M.G. Princen, Elly de Wit, Folkert Kuipers, Rick Havinga, J. Paul Zoeteweij, S.M. Post
Publikováno v:
Hepatology (Baltimore, Md.). 30(2)
Acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitors are currently in clinical development as potential lipid-lowering and antiatherosclerotic agents. We investigated the effect of avasimibe (Cl- 1011), a novel ACAT inhibitor, on bile acid s
Publikováno v:
Atherosclerosis. 141
To study the in vivo role of apolipoprotein (apo) C1 in lipoprotein metabolism, we have generated transgenic mice expressing the human apo C1 gene. Apo C1 is a small 6.6 kDa protein that is primarily synthesized by the liver and is present on chylomi
Publikováno v:
Biochemical Pharmacology, 2, 58, 263-271
We have shown previously that retinoids induce apolipoprotein (apo) A-I gene expression in cultured cynomolgus hepatocytes and do not have an effect on apo B-100 synthesis. In the present study, the effect of retinoids on apolipoprotein(a) (apo(a)) s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac3de72147f3a73a050151d0a2fead8
http://resolver.tudelft.nl/uuid:ef2a8fd2-3bb5-456a-88b5-6f321212c9e0
http://resolver.tudelft.nl/uuid:ef2a8fd2-3bb5-456a-88b5-6f321212c9e0
Autor:
Hans M.G. Princen, B. de Roos, Frans Stellaard, V.E.H. Dahlmans, L. Afman, M. Vermeulen, Martijn B. Katan, M. G. Jong, Louis M. Havekes, S. M. Posf
Publikováno v:
Hepatology 30 (1999) 4
Hepatology, 30(4), 319A-319A
Web of Science
Circulation 100 (1999) 18
Circulation, 100(18), 687-687
Hepatology, 30(4), 319A-319A
Web of Science
Circulation 100 (1999) 18
Circulation, 100(18), 687-687
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95bc286563dc5511c24791a727e5793
https://research.wur.nl/en/publications/cafestol-the-cholesterol-raising-factor-in-boiled-coffee-increase
https://research.wur.nl/en/publications/cafestol-the-cholesterol-raising-factor-in-boiled-coffee-increase
Autor:
W. van Duyvenvoorde, L.P.L. van de Vijver, Diederick E. Grobbee, G. van Poppel, A.F.M. Kardinaal, Hans M.G. Princen, D.A.C.M. Kruijssen
Publikováno v:
Free Radical Research, 2, 31, 129-139
Free Radical Research, 31, 129-139
Free Radical Research, 31, 129-139
Evidence has accumulated for oxidative modification of low-density lipoproteins (LDL) to play an important role in the atherogenic process. Therefore, we investigated the relation between susceptibility of LDL to oxidation and risk of peripheral athe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe3d3b87f2cdff4f448ac1854dd31b6
http://resolver.tudelft.nl/uuid:45d3e97f-e298-47ec-ab03-2d5ca8e745db
http://resolver.tudelft.nl/uuid:45d3e97f-e298-47ec-ab03-2d5ca8e745db