Zobrazeno 1 - 10
of 23
pro vyhledávání: '"George Hsiao"'
Autor:
Hui Wen Cheng, Jau Der Ho, Cheng Hui Lin, Ching Hao Li, Fan Li Lin, George Hsiao, Man Ru Wu, Yu Wen Cheng, Po Lin Liao, Shih Hsuan Huang, Chi Hao Tsai
Publikováno v:
Toxicological Sciences. 147:317-325
To determine the toxic effects of long-term topical usage of fluorometholone (FLM) on ganglion cells using a direct in vivo retinopathological Brown Norway (BN) rat model. The BN rat retinal model was investigated with a minimum of 3 rats and a maxim
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1810:475-484
Background Hypertonic stress enhances tumor necrosis factor (TNF)-α expression in activated monocytes. However, the underlying mechanism is unknown. The produced TNF-α is primarily cleaved and released by TNF-α-converting enzyme (TACE), and the su
Autor:
Chih-Jen Wu, Thanasekaran Jayakumar, George Hsiao, Ting-Lin Yen, Jui-Tai Chen, Joen Rong Sheu, Duen-Suey Chou
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2011 (2011)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Tao-Hong-Si-Wu-Tang (THSWT) is a famous traditional Chinese medicine (TMC). In the present study, oral administration of THSWT (0.7 and 1.4 gkg−1day−1) for 14 days before MCAO dose-dependently attenuated focal cerebral ischemia in rats. MCAO-indu
Autor:
Tsorng Harn Fong, George Hsiao, Hsin Yi Huang, Chen Ming Teng, Ming Yi Shen, Chien-Huang Lin, Joen Rong Sheu
Publikováno v:
Biochemical Pharmacology. 67:1411-1419
In the present study, the signal pathways involved in NO formation and iNOS expression in RAW 264.7 macrophages stimulated by LTA were investigated. We also compared the relative inhibitory activities and mechanisms of PMC, a novel potent antioxidant
Publikováno v:
Biochemical Pharmacology. 67:1337-1345
Andrographolide (Andro), an active component isolated from the Chinese official herbal Andrographis paniculata, which has been reported to prevent oxygen radical production and thus prevent inflammatory diseases. In this study, we investigated the mo
Autor:
George Hsiao, Shiow Lin Pan, Wen Chiung Chang, Tzeng Fu Chen, Yu Wen Cheng, Yueh-Hsiung Kuo, Ming Yi Shen, Joen Rong Sheu
Publikováno v:
Biochemical Pharmacology. 65:1383-1392
In the present study, we investigated the effects and mechanisms of a novel potent antioxidant, octyl caffeate, on the induction of iNOS expression by lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma) in cultured primary rat aortic smooth mus
Autor:
Chien-Huang Lin, Tzeng-Fu Chen, Wen Yi Lin, Chiu Ruey Tzeng, George Hsiao, Yi Yi Chien, Joen Rong Sheu
Publikováno v:
Journal of Biomedical Science. 9:17-25
There is substantial evidence of increased platelet reactivity in vivo and in vitro during pregnancy. Platelet activation occurs in pregnancy with a risk of the development of preeclampsia. In this study, platelet behavior was studied during 28-40 we
Autor:
George Hsiao, Fu Der Mai, Ying-Jui Ho, Hung Ming Chang, Wen Chieh Liao, Ting Yi Renn, Li You Chen, Ai Wei Lee
Publikováno v:
Journal of Pineal Research. 63:e12417
Prolonged exposure to gamma-hydroxybutyric acid (GHB) would cause drug intoxication in which impaired cognitive function results from enhanced hippocampal oxidative stress may serve as a major symptom in this deficiency. Considering melatonin possess
Publikováno v:
Journal of Pineal Research. 30:147-156
The pineal secretory product melatonin was found to exert protective effects in septic shock. In a host infected by bacterial lipopolysaccharide (LPS), the expression and release of proinflammatory tumor necrosis factor-alpha (TNF-alpha) is rapidly i
Publikováno v:
Thrombosis Research. 101:127-138
Monoclonal antibodies raised against beta(3) integrin are able to inhibit the binding of ligands to certain beta(3) integrins such as alpha(IIb)beta(3) (glycoprotein IIb/IIIa complex) and alpha(v)beta(3) (vitronectin receptor) and as such are inhibit