Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Cynthia D. Guy"'
Publikováno v:
Human Pathology. 116:63-72
Summary Primary hepatic neoplasms with neuroendocrine differentiation are extremely rare. Their clinicopathological features and molecular genetic basis are largely unknown. We identified four cases of primary hepatic neoplasms with neuroendocrine di
Autor:
Daniele Marin, Federica Vernuccio, Stephanie Austin, Priya S. Kishnani, Mathias Meyer, Cynthia D. Guy
Publikováno v:
World Journal of Clinical Cases
BACKGROUND Hepatocellular adenomas are rare tumors that can occur in patients with glycogen storage disease type I. CASE SUMMARY We herein report two cases of histologically proven hepatocellular adenomas in patients with glycogen storage disease typ
Autor:
Mathew M. Yeh, Cynthia D. Guy, Patricia Belt, Ryan M. Gill, Danielle Carpenter, Oscar W. Cummings, Laura A. Wilson, Daniela S. Allende, David E. Kleiner, Cynthia Behling, Samer Gawrieh, Mark L. Van Natta, Naga Chalasani
Publikováno v:
Liver International
Background/Aims Glycogen synthesis and storage are normal hepatocyte functions. However, glycogenosis, defined as excess hepatocyte glycogen visible by routine H&E light microscopy, has not been well characterized in nonalcoholic fatty liver disease
Autor:
Lei Zhao, Shu-Yuan Xiao, Diana M. Cardona, Cynthia D. Guy, Xuefeng Zhang, Liyan Xu, N. Lynn Ferguson, Maria Westerhoff, Amanda Hemmerich, John Hart, Cynthia L. Green, Beiyu Liu, Shannon J. McCall, Rish K. Pai
Publikováno v:
Virchows Archiv. 478:427-434
The diagnosis of invasive adenocarcinoma of the gallbladder can sometimes be challenging. The presence of true desmoplastic reaction facilitates the diagnosis of invasion. However, desmoplasia-like changes can be observed in benign gallbladder condit
Autor:
Anna Mae Diehl, Oliver Glass, Elizabeth Bechard, Jane F. Pendergast, Cynthia D. Guy, Daniel Liu, Manal F. Abdelmalek
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 6, Iss 2, Pp 334-344 (2022)
Hepatology Communications, Vol 6, Iss 2, Pp 334-344 (2022)
Exercise is a foundational treatment for nonalcoholic fatty liver disease (NAFLD); however, the majority of patients are unable to initiate and maintain effective exercise habits and remain at increased risk for progressive liver disease. Barriers an
Autor:
Cynthia D. Guy, Ying Wang, Anna Mae Diehl, Dana Portenier, Dawn Piercy, Matthew J Crowley, Andrea D. Coviello, Anastasia-Stefania Alexopoulos, Ranjan Sudan, Cynthia A. Moylan, Manal F. Abdelmalek, Keri A. Seymour, Ricardo Henao
Publikováno v:
Hepatology (Baltimore, Md.). 74(3)
BACKGROUND AND AIMS Whether glycemic control, as opposed to diabetes status, is associated with the severity of NAFLD is open for study. We aimed to evaluate whether degree of glycemic control in the years preceding liver biopsy predicts the histolog
Autor:
Wing-Kin Syn, Keyur Patel, Cynthia D. Guy, Anna Mae Diehl, Robert D. Streilein, Ricardo Henao, Oliver Glass, Hans J Gruss, Manal F. Abdelmalek, Cynthia A. Moylan, Russell P. Hall
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 2, Iss 11, Pp 1344-1355 (2018)
Hepatology Communications, Vol 2, Iss 11, Pp 1344-1355 (2018)
The severity of hepatic fibrosis is the primary predictor of liver‐related morbidity and mortality in patients with nonalcoholic fatty liver disease (NAFLD). Unfortunately, noninvasive serum biomarkers for NAFLD‐associated fibrosis are limited. W
Autor:
Ying Wang, Cynthia D. Guy, Cynthia A. Moylan, Anna Mae Diehl, Catherine F. Howe, Manal F. Abdelmalek, Ricardo Henao, Kara Wegermann
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 5, Iss 4, Pp 608-617 (2021)
Hepatology Communications, Vol 5, Iss 4, Pp 608-617 (2021)
Identifying patients at higher risk for poor outcomes from nonalcoholic fatty liver disease (NAFLD) remains challenging. Metabolomics, the comprehensive measurement of small molecules in biological samples, has the potential to reveal novel noninvasi
Autor:
Ying Wang, Anna Mae Diehl, Ricardo Henao, Manal F. Abdelmalek, Keri A. Seymour, Ranjan Sudan, Matthew J Crowley, Cynthia D. Guy, Anastasia-Stefania Alexopoulos, Dana Portenier, Andrea D. Coviello
Publikováno v:
Diabetes. 69
T2DM increases risk for advanced fibrosis in NAFLD, however little is known about the impact of glycemic control on fibrosis severity. Objective: To assess whether glycemic control is associated with severity of fibrosis in NAFLD. Methods: We utilize
Autor:
Kristin Nelson, Hsiao D. Lieu, Mildred Gottwald, James F. Trotter, Guy W. Neff, Nadege Gunn, Alex M. DePaoli, Sam E. Moussa, Ziad Younes, Andrew Yan, Mustafa R. Bashir, Angelo H. Paredes, Juan P. Frias, William C.G. Chang, Cynthia D. Guy, Stephen A. Harrison, Lei Ling, Anita Kohli
Publikováno v:
Gastroenterology. 160(1)
Background & Aims Aldafermin, an engineered analog of fibroblast growth factor 19, inhibits bile acid synthesis and regulates metabolic homeostasis. We report results from a 24-week, phase 2 study, with serial liver biopsies, of patients with nonalco