Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Chip Stewart"'
Autor:
Justin Cha, Cody J. Boehner, Nikhil C. Munshi, Romanos Sklavenitis-Pistofidis, Kwee Yong, Chip Stewart, Karma Salem, Eliezer M. Van Allen, Jihye Park, Yu-Tzu Tai, Andrew Dunford, Shankara Anand, Lorenzo Trippa, Amaro Taylor-Weiner, Jacob P. Laubach, Mark Bustoros, Benny Zhitomirsky, Robert A. Redd, Selina J Chavda, Irene M. Ghobrial, Shaji Kumar, Paul G. Richardson, Kenneth C. Anderson, François Aguet, Tarek H. Mouhieddine, P. Leif Bergsagel, Gad Getz, Mahshid Rahmat, Tineke Casneuf, Meletios A. Dimopoulos, Liudmila Elagina, Carl Jannes Neuse, Salomon Manier, Elizabeth A. Morgan, Ignaty Leshchiner, Efstathis Kastritis
Publikováno v:
J Clin Oncol
PURPOSE Smoldering multiple myeloma (SMM) is a precursor condition of multiple myeloma (MM) with a 10% annual risk of progression. Various prognostic models exist for risk stratification; however, those are based on solely clinical metrics. The disco
Autor:
Robert A. Redd, Matthew Leventhal, Irene M. Ghobrial, Nikhil C. Munshi, Christopher J. Gibson, Jerome Ritz, Amin Nassar, Chip Stewart, Jihye Park, Romanos Sklavenitis-Pistofidis, Marzia Capelletti, Cody J. Boehner, David P. Steensma, Saud H. AlDubayan, Daniel Auclair, Lorenzo Trippa, Muhieddine M. Itani, Benjamin L. Ebert, Kalvis Hornburg, Shaadi Mehr, Mark Bustoros, Robert L. Schlossman, Henry Dumke, Jacob P. Laubach, Adam S. Sperling, Gad Getz, Salomon Manier, Paul G. Richardson, Eliezer M. Van Allen, Tarek H. Mouhieddine, Sabrin Tahri, Kenneth C. Anderson, Robert J. Soiffer, Daisy Huynh, Donna Neuberg, Brendan Reardon, Chia Jen Liu, Jonathan J Keats
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.2996. ⟨10.1038/s41467-020-16805-5⟩
Nature Communications, 2020, 11 (1), pp.2996. ⟨10.1038/s41467-020-16805-5⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.2996. ⟨10.1038/s41467-020-16805-5⟩
Nature Communications, 2020, 11 (1), pp.2996. ⟨10.1038/s41467-020-16805-5⟩
Multiple myeloma (MM) is a plasma-cell neoplasm that is treated with high-dose chemotherapy, autologous stem cell transplant (ASCT) and long-term immunomodulatory drug (IMiD) maintenance. The presence of somatic mutations in the peripheral blood is t
Autor:
Tetiana Bogdanova, Vidushi Kapoor, Mykola Chepurny, Stephen W. Hartley, Yosef E. Maruvka, Danielle M. Karyadi, Sara J. Schonfeld, Meredith Yeager, Casey L. Dagnall, Lindsay M. Morton, Eric T. Dawson, Elizabeth K. Cahoon, Kiyohiko Mabuchi, Marko Krznaric, Charles M. Perou, Gad Getz, Julie M. Gastier-Foster, Vladimir Drozdovitch, Amy Berrington de Gonzalez, Juan Carvajal-Garcia, Gerry Thomas, Sergii Masiuk, Joshua N. Sampson, Joseph Boland, Stephen J. Chanock, Mitchell J. Machiela, Belynda Hicks, Olivia W. Lee, Joel S. Parker, Amy Hutchinson, Liudmyla Yu Zurnadzhy, Jay Bowen, Jieqiong Dai, Mykola Tronko, Mia Steinberg, Maureen Hatch, Chip Stewart, Dale A. Ramsden, Alina V. Brenner
Publikováno v:
Science
Genomics of radiation-induced damage The potential adverse effects of exposures to radioactivity from nuclear accidents can include acute consequences such as radiation sickness, as well as long-term sequelae such as increased risk of cancer. There h
Autor:
Zhenwei Zhang, Laura Polacek, Sara M. Tolaney, Joshua M. Francis, Samuel S. Freeman, Paz Polak, Rachel Leeson, J. Christopher Love, Huiming Ding, Sairah Mahmud, Nelly Oliver, Rachel M. Barry, Atish D. Choudhury, Levi A. Garraway, Gregory Gydush, Andrea Saltzman, Eliezer M. Van Allen, Coyin Oh, Viktor A. Adalsteinsson, Justin Rhoades, Jesse S. Boehm, Sarah C. Reed, Seong Ho Jeong, Todd R. Golub, Karla Helvie, Matthew Meyerson, Lauren C. Harshman, Gad Getz, Ignaty Leshchiner, Jens G. Lohr, Chip Stewart, Heather A. Parsons, Jaegil Kim, Adrienne G. Waks, Mari Nakabayashi, Lori Marini, Mara Rosenberg, Edward P. O’Connor, Daniel Rosebrock, Denis Loginov, Daniel G. Stover, Rebecca A. Santiago, Nikhil Wagle, Joseph F. Kramkowski, Mary-Ellen Taplin, Eric P. Winer, Nan Lin, Ofir Cohen, Cheng-Zhong Zhang, Dimitri Livitz, Emily Lipscomb, Gavin Ha, Molly Schleicher, Denisse Rotem, Max Lloyd, Margaret S. Merrill, Cory M. Johannessen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature Communications
Whole-exome sequencing of cell-free DNA (cfDNA) could enable comprehensive profiling of tumors from blood but the genome-wide concordance between cfDNA and tumor biopsies is uncertain. Here we report ichorCNA, software that quantifies tumor content i
Autor:
Valsamo Anagnostou, Nir Hacohen, Mark M. Awad, Patrick M. Forde, Julie R. Brahmer, Jedd D. Wolchok, Jaegil Kim, Ignaty Leshchiner, Roy S. Herbst, Alice T. Shaw, Kurt A. Schalper, John V. Heymach, Pasi A. Jänne, Arvind Ravi, Vamsidhar Velcheti, Monica Arniella, Naiyer A. Rizvi, Subba R. Digumarthy, Chip Stewart, Don L. Gibbons, Samuel S. Freeman, Brian S. Henick, Gad Getz, Jonathan W. Riess, Matthew D. Hellman, Justin F. Gainor, Mari Mino-Kenudson, Victor E. Velculescu, Nathan A. Pennell
Publikováno v:
Cancer Research. 81:LB197-LB197
The advent of PD-1/PD-L1 agents has transformed the therapeutic landscape of many advanced cancers, including non-small cell lung cancer (NSCLC). However, our understanding of the genomic biomarkers underlying effective treatment response remain limi
Autor:
Chuck Perou, Marko Krznaric, Sergii Masiuk, Tetiana Bogdanova, Jieqiong Dai, Vladimir Drozdovitch, Julie M. Gastier-Foster, Lindsay M. Morton, Casey L. Dagnall, Juan Carvajal-Garcia, Elizabeth K. Cahoon, Stephen Hartley, Joseph Boland, Maureen Hatch, Stephen J. Chanock, Olivia W. Lee, Joel S. Parker, Mitchell J. Machiela, Eric T. Dawson, Mykola Tronko, Kiyohiko Mabuchi, Mia Steinberg, Chip Stewart, Gad Getz, Dale A. Ramsden, Amy Hutchinson, Liudmyla Yu Zurnadzhy, Alina V. Brenner, Jay Bowen, Belynda Hicks, Sara J. Schonfeld, Amy Berrington de Gonzalez, Gerry Thomas, Danielle M. Karyadi, Meredith Yeager, Mykola Chepurny, Joshua N. Sampson, Vidushi Kapoor, Yosi Maruvka
Publikováno v:
Clinical Cancer Research. 27:PO-055
The 1986 Chernobyl nuclear power plant accident increased papillary thyroid cancer (PTC) incidence in surrounding regions, particularly for 131I-exposed children. To investigate the contribution of environmental radiation to PTC characteristics and i
Autor:
Mahshid Rahmat, Meletios A. Dimopoulos, Yu-Tzu Tai, Shaji Kumar, Paul G. Richardson, Robert A. Redd, Alex Barbera, Gad Getz, Christopher Chiu, Salomon Manier, Selina Chavada, Nikhil C. Munshi, Tarek H. Mouhieddine, Irene M. Ghobrial, Elizabeth A. Morgan, Jihye Park, Andrew Dunford, Binyamin Zhitomirsky, Chip Stewart, Romanos Sklavenitis-Pistofidis, Cody J. Boehner, Kwee Yong, David Soong, François Aguet, Mark Bustoros, Adriana Peilla Glen, Kenneth C. Anderson, Jacob P. Laubach, Carl Jannes Neuse, Efstathios Kastritis, Lorenzo Trippa, Eliezer M. Van Allen
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 19:e5-e6
Autor:
Sara Seepo, Kyle Beckman, Clifford M. Takemoto, Todd Cooper, Johann Hitzler, Philip A. Roehrs, Todd R. Golub, Tiffany Y. Chang, Scott R. Olsen, Tali Mazor, Patrick A. Brown, Robert J. Hayashi, Mara Rosenberg, Reuven J. Schore, Rakesh K. Goyal, Philip M. Monteleone, Emilio Esquivel, Jeffrey A. Toretsky, Elliot Stieglitz, Robert B. Gerbing, Mignon L. Loh, Adam B. Olshen, Gad Getz, Yong Dong Wang, Yongjin Li, Benjamin Carcamo, Laura C. Gelston, Kimo C. Stine, Ghada Abusin, Chip Stewart, Peter D. Emanuel, Todd A. Alonzo, Y. Lucy Liu, Yoav Messinger, Gary V. Dahl, Joseph F. Costello, Kimberly Stegmaier, Christopher Hugge, Donald H. Mahoney, Jing Ma, Eneida R. Nemecek, Sophie Archambeault, Amaro Taylor-Weiner, Ariel Yu, Mark Fluchel, Tanja A. Gruber, Michael Briones
Publikováno v:
Nature genetics
Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative neoplasm (MPN) of childhood with a poor prognosis. Mutations in NF1, NRAS, KRAS, PTPN11 and CBL occur in 85% of patients, yet there are currently no risk stratification algorithms capabl
Autor:
John V. Heymach, Monica Arniella, Jaegil Kim, Chip Stewart, Matthew D. Hellmann, Julie R. Brahmer, Vamsidhar Velcheti, Pasi A. Jänne, Brian S. Henick, Naiyer A. Rizvi, Don L. Gibbons, Nir Hacohen, Valsamo Anagnostou, Patrick M. Forde, Jonathan W. Riess, Gad Getz, Roy S. Herbst, Kurt A. Schalper, Mark M. Awad, Ignaty Leshchiner, Samuel S. Freeman, Nathan A. Pennell, Jedd D. Wolchok, Subba R. Digumarthy, Arvind Ravi, Victor E. Velculescu, Alice T. Shaw, Justin F. Gainor, Mari Mino-Kenudson
Publikováno v:
Cancer Research. 80:5902-5902
PD-1/PD-L1 checkpoint blockade has been a landmark advance for many patients suffering from advanced non-small cell lung cancer (NSCLC). However, detailed biomarkers of response beyond tumor mutational burden (TMB) are still poorly understood. As par
Autor:
Donna Neuberg, Xose S. Puente, Chip Stewart, Gad Getz, Ziao Lin, Binyamin A. Knisbacher, Elias Campo, José I. Martín-Subero, Cynthia K. Hahn, Catherine J. Wu, Kristen E. Stevenson
Publikováno v:
Cancer Research. 80:169-169
Chronic lymphocytic leukemia (CLL) accounts for one third of all diagnosed leukemias. It exhibits tremendous clinical variability, ranging from indolent disease kinetics to a fast progressing aggressive disease. Two large-scale studies by our groups,