Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Charles R. Mackay"'
Autor:
Matthew Snelson, Gavin W. Lambert, Assam El-Osta, Grant R Drummond, D. Donner, Melinda T. Coughlan, Helen Kiriazis, Aanthony Vinh, Duncan Horlock, Charles R. Mackay, Waled A. Shihata, Hamdi A. Jama, Beverly Giam, Tim D. Spector, Chad Johnson, Mark Ziemann, Xiao-Jun Du, April Fiedler, Kirill Tsyganov, Francine Z. Marques, David M. Kaye, Sarah E. Phillips, Amrita Vijay, Ana M. Valdes
Publikováno v:
Circulation. 141:1393-1403
Background: High blood pressure (BP) continues to be a major, poorly controlled but modifiable risk factor for cardiovascular death. Among key Western lifestyle factors, a diet poor in fiber is associated with prevalence of high BP. The impact of lac
Autor:
Sara Bordbar, Charles R. Mackay, Stephen M. Twigg, Eliana Mariño, Shannon Brodie, Sonia Saad, Marc R. Wilkins, Barbara Fazekas de St Groth, Long T. Nguyen, Emma E. Hamilton-Williams, Bree J. Tillett, Susan M. Corley, Courtney J. Wright, Helen M. McGuire, Yu Anne Yap, Kirstine J. Bell, Sussan Duong, Esteban Nicolas Gurzov, Leonard C. Harrison
BackgroundShort-chain fatty acids (SCFAs) produced by the gut microbiota have beneficial anti-inflammatory and gut homeostasis effects and prevent type 1 diabetes (T1D) in mice. Reduced SCFA production indicates a loss of beneficial bacteria, commonl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81d99ceb0bb773c049b35a111f8cd051
https://doi.org/10.1101/2021.09.15.21263059
https://doi.org/10.1101/2021.09.15.21263059
Autor:
Melinda T. Coughlan, Waled A. Shihata, Louise M Burrell, Charles R. Mackay, Francine Z. Marques, Rikeish R. Muralitharan, Michael E Nakai, Matthew Snelson, David M. Kaye, Hamdi A. Jama, Chad Johnson, Evany Dinakis
Publikováno v:
Hypertension. 77
Autor:
Yanjun Li, Xiaochen Chen, Yunzi Liu, Tony Kwan, Yik Wen Loh, Steven J. Chadban, Huiling Wu, Julian Singer, Laurence Macia, Jian Tan, Jin Ma, Charles R. Mackay
Publikováno v:
J Am Soc Nephrol
Background Studies have reported "dysbiotic" changes to gut microbiota, such as depletion of gut bacteria that produce short-chain fatty acids (SCFAs) through gut fermentation of fiber, in CKD and diabetes. Dietary fiber is associated with decreased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e509d83eb26d18d4a7b8c46ff013e92
https://europepmc.org/articles/PMC7269358/
https://europepmc.org/articles/PMC7269358/
Autor:
Steven Joung, Michael J. Peek, Ron Benzie, Charles R. Mackay, Kahlia Wong, David P. Eviston, Martin O'Hely, Eliana Mariño, Mingjing Hu, Yu Anne Yap, James L. Richards, David Wilson, Ann Louise Ponsonby, Ralph Nanan, Peter Hsu, Ann Quinton, Ann P. Chidgey, Peter Vuillermin, Mimi L.K. Tang, Jane E. Dahlstrom, Brigitte Santner-Nanan, Norelle L. Daly, Laurence Macia, Fiona Collier
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Maternal immune dysregulation seems to affect fetal or postnatal immune development. Preeclampsia is a pregnancy-associated disorder with an immune basis and is linked to atopic disorders in offspring. Here we show reduction of fetal thymic size, alt
Autor:
Izabel Cristina de Matos Andrade, Angélica T. Vieira, Tarcília Aparecida Silva, Soraia Macari, Charles R. Mackay, M.M. Teixeira, S de Oliveira, J.A.A. de Arruda, Gustavo Pompermaier Garlet, Sandra Y. Fukada, Marina Campos Zicker, Marco Aurélio Ramirez Vinolo, Mila Fernandes Moreira Madeira, Letícia Fernanda Duffles, Carina Cristina Montalvany-Antonucci
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Short-chain fatty acids (SCFAs) exert a variety of immune and metabolic functions by binding to G-protein-coupled receptors, mainly free fatty acid receptor 2 (FFAR2). However, the effects of SCFAs and FFARs on bone remodeling, especially in alveolar
Autor:
Luciana P. Tavares, Laurence Macia, Izabela Galvão, Flaviano S. Martins, Flávio A. Amaral, Charles R. Mackay, Erica M. Sernaglia, Lirlândia P. Sousa, Angélica T. Vieira, Marco Aurélio Ramirez Vinolo, Cristiana C. Garcia, Mauro Martin Teixeira
Publikováno v:
Repositório Institucional da UFMG
Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais INCT – Instituto nacional de ciência e tecnologia (Antigo Instituto do Milênio) Gout is a disease characte
Autor:
Charles R. Mackay, Simon Bulley, Qian Wang, Carlos Fernández-Peña, Kirk W. Evanson, Raquibul Hasan, Jonathan H. Jaggar, M. Dennis Leo, Padmapriya Muralidharan, Sarah K. Burris, Korah P. Kuruvilla
Publikováno v:
Web of Science
Systemic blood pressure is determined, in part, by arterial smooth muscle cells (myocytes). Several Transient Receptor Potential (TRP) channels are proposed to be expressed in arterial myocytes, but it is unclear if these proteins control physiologic
Autor:
Raghavendra G. Mirmira, Medha Priyadarshini, Charles R. Mackay, Thierry Alquier, Annette Gilchrist, Helena Mancebo, Barton Wicksteed, Vincent Poitout, Miles Fuller, Stephanie R. Villa, Brian T. Layden
Publikováno v:
Molecular Endocrinology. 29:1055-1066
G protein-coupled receptors have been well described to contribute to the regulation of glucose-stimulated insulin secretion (GSIS). The short-chain fatty acid-sensing G protein-coupled receptor, free fatty acid receptor 2 (FFAR2), is expressed in pa
Autor:
Katherine Wood, Charles R. Mackay, Yoshihiro Miwa, Tri Giang Phan, Henry R. Hampton, Michio Tomura, Tatyana Chtanova, Robert Brink, Louise A. Waterhouse
Publikováno v:
Journal of Biophotonics. 7:425-433
The potential usefulness of intravital two-photon microscopy for fate mapping is limited by its inability to track cells beyond the confines of the imaging volume. Therefore, we have developed and validated a novel method for in vivo photolabelling o