Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Andres J. Klein-Szanto"'
Publikováno v:
Biochemical Pharmacology. 164:336-341
Hypercholesterolemia represents a leading cause in the development of atherosclerotic plaques, increasing the risk for ACVS. It actually counts as a major cause of cardiovascular disease etiopathogenesis. The causes of hypercholesterolemia are multif
Autor:
Manabu Muto, Masataka Shimonosono, Takaaki Arigami, Amanda B. Muir, Masaki Mori, Takashi Kijima, Yuta Kasagi, Shinya Ohashi, Andres J. Klein-Szanto, Prasanna M. Chandramouleeswaran, Narayan G. Avadhani, Itaru Omoto, Shoji Natsugoe, Gregory G. Ginsberg, Seiji Naganuma, Veronique Giroux, Varun Sahu, Yoshiaki Shinden, Osamu Kikuchi, Devraj Basu, J. Alan Diehl, Yasuto Uchikado, Koji Tanaka, Yoshiaki Kita, Yuichiro Doki, Adam J. Bass, Ken Sasaki, Hiroshi Nakagawa, Anil K. Rustgi, Kelly A. Whelan, Takeo Hara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Background & Aims Oropharyngeal and esophageal squamous cell carcinomas, especially the latter, are a lethal disease, featuring intratumoral cancer cell heterogeneity and therapy resistance. To facilitate cancer therapy in personalized medicine, thre
Autor:
Kelly A. Whelan, Benjamin J. Wilkins, Okan U. Elci, Evan S. Dellon, Gary W. Falk, Jonathan Gross, Bridget Godwin, Andres J. Klein-Szanto, Hiroshi Nakagawa, Jonathan M. Spergel, Maureen DeMarshall, Amanda B. Muir, Medha Sharma, Alain Benitez, Chris A. Liacouras
Publikováno v:
Clin Gastroenterol Hepatol
Background & Aims Although eosinophil count is the standard used to monitor disease activity in patients with eosinophilic esophagitis (EoE), there are often disparities between patient-reported symptoms and eosinophil counts. We examined the prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9caf01105763de1fa0d9d57e16578429
https://europepmc.org/articles/PMC7058491/
https://europepmc.org/articles/PMC7058491/
Autor:
Andres J. Klein-Szanto, Javier S. Castresana, Daniel E. Bassi, Gary Thomas, Ricardo Lopez de Cicco, Javier Mercapide
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(8)
Purpose: Astrocytoma arises in the central nervous system as a tumorof great lethality, in part because of the invasive potential of the neoplastic cells that are able to release extracellular matrix-degrading enzymes. Furin convertase activates seve
Autor:
Craig W. Menges, Mitchell Cheung, Kathy Q. Cai, Andres J. Klein-Szanto, Eleonora Sementino, Frank J. Rauscher, Yuwaraj Kadariya, Jinfei Xu, Joseph R. Testa, Jianming Pei
Publikováno v:
Cancer Research. 76:2836-2844
Individuals harboring inherited heterozygous germline mutations in BAP1 are predisposed to a range of benign and malignant tumor types, including malignant mesothelioma, melanoma, and kidney carcinoma. However, evidence to support a tumor-suppressive
Autor:
Takeo Hara, Hiroshi Nakagawa, Masataka Shimonosono, Dominique Bailey, Julian A. Abrams, Rieko Shimonosono, Melanie A. Ruffner, Manti Guha, Andres J. Klein-Szanto, Jianwen Que, Gary W. Falk, Hisatsugu Maekawa, Amanda B. Muir, Jonathan M. Spergel
Publikováno v:
Gastroenterology. 158:S-178
Autor:
Kathryn E. Hamilton, Koji Tanaka, Veronique Giroux, Hiroshi Nakagawa, Marie Pier Tetreault, Ju Seog Lee, Apple Long, Andres J. Klein-Szanto, Anil K. Rustgi, Kelly A. Whelan
Publikováno v:
Carcinogenesis. 36:598-606
Esophageal cells overexpressing epidermal growth factor receptor (EGFR) and TP53 mutation can invade into the extracellular matrix when grown in 3D-organotypic cultures (OTC) and mimic early invasion in esophageal squamous cell carcinoma (ESCC). We h
Publikováno v:
Molecular Carcinogenesis. 54:1122-1131
PACE4 (PCSK6) is a proprotein convertase (PC) capable of processing numerous substrates involved in tumor growth, invasion, and metastasis. Because of the human relevancy of the tobacco-associated carcinogen benzo[a]pyrene (B(a)P) we investigated whe
Autor:
Joseph R. Testa, Jacqueline Talarchek, Erin Neumann-Domer, Deborah A. Altomare, Yue Wu, Craig W. Menges, Guang-Hui Xiao, Vihren N. Kolev, Yuwaraj Kadariya, Irina M. Shapiro, Jonathan A. Pachter, Andres J. Klein-Szanto
Publikováno v:
Cancer Research. 74:1261-1271
Malignant mesothelioma is a highly aggressive, asbestos-related cancer frequently marked by mutations of both NF2 and CDKN2A. We demonstrate that germline knockout of one allele of each of these genes causes accelerated onset and progression of asbes
Autor:
Miriam N. Lango, Brian L. Egleston, Carolyn Y. Fang, Jamie L. Studts, Margret B. Einarson, Dana H. Bovbjerg, John A. Ridge, Andres J. Klein-Szanto, Barbara Burtness
Publikováno v:
Head & Neck. 36:1113-1119
Background Psychosocial functioning is associated with vascular endothelial growth factor (VEGF) in various patient populations. This study examined whether psychosocial functioning in patients with head and neck squamous cell carcinoma (HNSCC) is as