Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Allison Berger"'
Autor:
Thea Kalebic, Neeraj Gupta, Lillian L. Siu, John S. Kauh, David Smith, Feng Gao, Ai Min Hui, Jeffrey R. Infante, Gordana Vlahovic, Allison Berger, Jianchang Lin, John A. Thompson, Deborah Berg, Guohui Liu, Stephen Tirrell, Daniel C. Sullivan, Alessandra Di Bacco
Publikováno v:
Investigational New Drugs
SummaryPurpose Ixazomib is an investigational proteasome inhibitor with demonstrated antitumor activity in xenograft models of multiple myeloma (MM), lymphoma, and solid tumors. This open-label, phase 1 study investigated intravenous (IV) ixazomib, i
Autor:
Mitchell R. Smith, Catherine Diefenbach, Kevin R. Kelly, Andrzej Jakubowiak, Zhaowei Hua, R. Donald Harvey, Sagar Lonial, Daniel Lebovic, Bruce J. Dezube, George Mulligan, Hélène M. Faessel, Owen A. O'Connor, Jatin J. Shah, Stephen Tirrell, Robert Z. Orlowski, Allison Berger
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 22(1)
Purpose: Evaluate the safety, pharmacokinetic profile, pharmacodynamic effects, and antitumor activity of the first-in-class investigational NEDD8-activating enzyme (NAE) inhibitor pevonedistat (TAK-924/MLN4924) in patients with relapsed/refractory l