Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ziyang Cao"'
Publikováno v:
ACS applied materialsinterfaces. 13(29)
Immunotherapy has revolutionized the therapeutic modalities of cancer treatment but is severely limited by a low objective response rate and the risk of immune-related side effects. Herein, an injectable supramolecular hydrogel is developed for local
Autor:
Yinchu Ma, Ziyang Cao, Xianzhu Yang, Zi-Dong Lu, Zeyu Yao, Dongdong Li, Youyong Yuan, Junxia Wang, Chun-Yang Sun
Publikováno v:
Chemistry of Materials. 30:517-525
Drug delivery systems with remotely controlled drug release capability are rather attractive options for cancer therapy. Herein, a reactive oxygen species (ROS)-sensitive polymeric nanocarrier TK-PPE@NPCe6/DOX was explored to realize remotely control
Autor:
Xianzhu Yang, Tianmeng Sun, Xianying Meng, Xin Wang, Chenxi Wu, Hongmei Chen, Xiuxiu Cong, Li Yong, Yong-Guang Yang, Xu Sun, Jialiang Wang, Kuirong Mao, Ziyang Cao
Publikováno v:
Biomaterials. 240:119845
Photodynamic therapy (PDT) can destroy local tumor cells and induce effective antitumor immune responses, and has been applied in the treatment of patients with superficial solid tumors. Numerous systemic side effects of PDT, such as pain and skin ph
Enhancement of chemosensitivity by WEE1 inhibition in EGFR-TKIs resistant non-small cell lung cancer
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 117, Iss, Pp-(2019)
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) is the first-line treatment in non-resectable non-small lung cancer (NSCLC) with EGFR mutation. However, EGFR-TIKs resistance would inevitably develop within 9–14 months afte
Autor:
Xiao-Hui Jiang, Zhongwei Lv, Yu-Shui Ma, Fei Yu, Xiao-Jun Zhong, Gai-Xia Lu, Likun Hou, Wen-Ting Xie, Chunyan Wu, Da Fu, Wei Wu, Ziyang Cao, Hai-Min Lu, Min-Xin Shi, Junjian Jiang, Zhi-Jun Wu, Gu-Jun Cong, Yingchun Song, Ji-Bin Liu, Cheng-You Jia, Li Chai
Publikováno v:
Cancer letters. 427
Increasing evidence has shown that microRNAs (miRNAs) play a significant functional role by directly regulating respective targets in cancer stem cell (CSC)-induced non-small cell lung cancer (NSCLC) progression and resistance to therapy. In this stu
Autor:
Jin Gu, Jiadong Wang, Ming Tang, Chaohua Zhang, Ziyang Cao, Tianyun Hou, Bo Tu, Jianyuan Luo, Yinglu Li, Wei-Guo Zhu, Lu Jiang, Xingzhi Xu, Changzheng Du, Baohua Liu, Lin-Lin Cao, Yongcan Chen, Hui Wang, Haiying Wang, Lina Wang, Zhiming Li, Xiaopeng Lu
Publikováno v:
Theranostics
5-Fluorouracil (5-FU) combined with radiotherapy is a common treatment strategy to treat human cancers, but the underlying mechanisms of this combination treatment remain unclear. Here, we report that NAD+-dependent deacetylase sirtuin-7 (SIRT7) prot
Publikováno v:
Biomaterials science. 4(3)
Redox-responsive polymers exhibit great potential as drug delivery systems. Herein, a redox-responsive PEGylated hyperbranched polyphosphoester (PPE) was synthesized through (A2 + B3) type polycondensation. The obtained hyperbranched PPE can self-ass