Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Tom W"'
Publikováno v:
Rheumatology and Therapy
Although treatment with biologic disease-modifying antirheumatic drugs (bDMARDs) has significantly improved clinical outcomes in patients with rheumatoid arthritis (RA), many patients do not have access to these treatments. As cost-effective alternat
Autor:
Tom W J Huizinga, Maarten K. Ninaber, Jeska K de Vries-Bouwstra, M. Boonstra, Anne A. Schouffoer, Nina M van Leeuwen, Lucia J.M. Kroft, Jacopo Ciaffi
Publikováno v:
Arthritis Care and Research, 74(3), 433-441. WILEY
Objective Hematopoietic stem cell transplantation (HSCT) and cyclophosphamide (CYC) are treatment options for progressive systemic sclerosis associated with interstitial lung disease (SSc-ILD). The aims of our retrospective observational study were t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b9d1b056938b62e7d02c3f7815dcca
http://hdl.handle.net/1887/3250645
http://hdl.handle.net/1887/3250645
Autor:
J. M. Maassen, Raquel Dos Santos Sobrín, Sytske Anne Bergstra, R.J. Goekoop, Tom W J Huizinga, Cornelia F Allaart
Publikováno v:
Annals of the Rheumatic Diseases, 80(9), 1124-1129. BMJ PUBLISHING GROUP
ObjectivesTo evaluate the success rate of glucocorticoid discontinuation and to study which factors are associated with successful discontinuation.MethodsData from two treat-to-target studies, BeSt (target Disease Activity Score (DAS) ≤2.4) and IMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2adee45f34febd846c2c359637c4260
https://doi.org/10.1136/annrheumdis-2021-220403
https://doi.org/10.1136/annrheumdis-2021-220403
Autor:
Maarten K. Ninaber, Tom W J Huizinga, Jeska K de Vries-Bouwstra, Sophie I E Liem, Henrike van Dongen, Jacopo Ciaffi, M. Maurits, Nina M van Leeuwen, Cornelia F Allaart, Rachel Knevel, R.J. Goekoop, Nina Ajmone Marsan
Publikováno v:
RMD Open
RMD Open, 7(2). BMJ PUBLISHING GROUP
RMD Open, Vol 7, Iss 2 (2021)
RMD Open, 7(2). BMJ PUBLISHING GROUP
RMD Open, Vol 7, Iss 2 (2021)
ObjectivesTo develop a prediction model to guide annual assessment of systemic sclerosis (SSc) patients tailored in accordance to disease activity.MethodsA machine learning approach was used to develop a model that can identify patients without disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7e8fe695657b3c0d0e10a4286cab97
https://hdl.handle.net/1887/3196226
https://hdl.handle.net/1887/3196226
Autor:
Andrew R. D’Avino, Martin Filipovski, John D. Bagert, Hai T. Dao, Akshay Sankar, Nazar Mashtalir, Hengyuan Liu, Brittany C. Michel, Aaron J. Corin, Cigall Kadoch, Eva J. Ge, Geoffrey P. Dann, Tom W. Muir
Publikováno v:
Signal Transduction and Targeted Therapy
Chromatin landscape dictates remodeling Large, multicomponent molecular machines known as mammalian SWI/SNF (mSWI/SNF) chromatin-remodeling complexes play critical roles in governing the architecture of our genomes. These entities bind to chromatin (
Autor:
Caroline Trang, Salima Hacein-Bey Abina, Malin Ryner, Florian Deisenhammer, Manuel Comabella, Abiba Doukani, Philippe Broët, Anna Fogdell-Hahn, Julianne Duhaze, Hans-Peter Hartung, Clemens Warnke, Natacha Szely, Delphine Bachelet, Alessandra Vultaggio, Bernd C. Kieseier, Sebastian Spindeldreher, Olivier Brocq, Poul Erik Hyldgaard-Jensen, Michael Auer, Marc Pallardy, Matthieu Allez, Mary Birchler, Tom W J Huizinga, Yehuda Chowers, Yoram Bouhnik, Dorothea Buck-Martin, Elizabeth C. Jury, Amy Loercher, Dan Sikkema, Aude Gleizes, Tobias Derfuss, Jessica J Manson, Guillaume Cadiot, Claudia Sievers, Michael Khalil, Naoimh Donnellan, Raija L.P. Lindberg, Agnès Hincelin Mery, Badreddine Mohand Oumoussa, Enrico Maggi, Martin Soubrier, Kathleen Ingenhoven, Orhan Aktas, Sophie Tourdot, Xavier Montalban, Maria Nachury, Niek de Vries, Timothy P. Hickling, Christophe Richez, Bernhard Hemmer, Franck Carbonnel, Finn Sellebjerg, Jérôme Avouac, Petra Nytrova, Xavier Mariette, Anna Lauren, Signe Hässler, Pierre Dönnes, Eva Havrdova, Michael Guger, Claudia Mauri
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
PLoS Medicine
PLoS Medicine, 17(10). PUBLIC LIBRARY SCIENCE
PLoS Medicine, 2020, 17 (10), pp.e1003348. ⟨10.1371/journal.pmed.1003348⟩
Hässler, S, Bachelet, D, Duhaze, J, Szely, N, Gleizes, A, Hacein-Bey Abina, S, Aktas, O, Auer, M, Avouac, J, Birchler, M, Bouhnik, Y, Brocq, O, Buck-Martin, D, Cadiot, G, Carbonnel, F, Chowers, Y, Comabella, M, Derfuss, T, De Vries, N, Donnellan, N, Doukani, A, Guger, M, Hartung, H-P, Kubala Havrdova, E, Hemmer, B, Huizinga, T, Ingenhoven, K, Hyldgaard-Jensen, P E, Jury, E C, Khalil, M, Kieseier, B, Laurén, A, Lindberg, R, Loercher, A, Maggi, E, Manson, J, Mauri, C, Mohand Oumoussa, B, Montalban, X, Nachury, M, Nytrova, P, Richez, C, Ryner, M, Sellebjerg, F, Sievers, C, Sikkema, D, Soubrier, M, Tourdot, S, Trang, C, Vultaggio, A & ABIRISK Consortium 2020, ' Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease : A prospective multicohort study of the ABIRISK consortium ', PLoS Medicine, vol. 17, no. 10, e1003348 . https://doi.org/10.1371/journal.pmed.1003348
PLoS Medicine, Public Library of Science, 2020, 17 (10), pp.e1003348. ⟨10.1371/journal.pmed.1003348⟩
PLoS Medicine, Vol 17, Iss 10, p e1003348 (2020)
PLoS medicine, 17(10):e1003348. Public Library of Science
Universitat Autònoma de Barcelona
PLoS Medicine
PLoS Medicine, 17(10). PUBLIC LIBRARY SCIENCE
PLoS Medicine, 2020, 17 (10), pp.e1003348. ⟨10.1371/journal.pmed.1003348⟩
Hässler, S, Bachelet, D, Duhaze, J, Szely, N, Gleizes, A, Hacein-Bey Abina, S, Aktas, O, Auer, M, Avouac, J, Birchler, M, Bouhnik, Y, Brocq, O, Buck-Martin, D, Cadiot, G, Carbonnel, F, Chowers, Y, Comabella, M, Derfuss, T, De Vries, N, Donnellan, N, Doukani, A, Guger, M, Hartung, H-P, Kubala Havrdova, E, Hemmer, B, Huizinga, T, Ingenhoven, K, Hyldgaard-Jensen, P E, Jury, E C, Khalil, M, Kieseier, B, Laurén, A, Lindberg, R, Loercher, A, Maggi, E, Manson, J, Mauri, C, Mohand Oumoussa, B, Montalban, X, Nachury, M, Nytrova, P, Richez, C, Ryner, M, Sellebjerg, F, Sievers, C, Sikkema, D, Soubrier, M, Tourdot, S, Trang, C, Vultaggio, A & ABIRISK Consortium 2020, ' Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease : A prospective multicohort study of the ABIRISK consortium ', PLoS Medicine, vol. 17, no. 10, e1003348 . https://doi.org/10.1371/journal.pmed.1003348
PLoS Medicine, Public Library of Science, 2020, 17 (10), pp.e1003348. ⟨10.1371/journal.pmed.1003348⟩
PLoS Medicine, Vol 17, Iss 10, p e1003348 (2020)
PLoS medicine, 17(10):e1003348. Public Library of Science
Background Biopharmaceutical products (BPs) are widely used to treat autoimmune diseases, but immunogenicity limits their efficacy for an important proportion of patients. Our knowledge of patient-related factors influencing the occurrence of antidru
Autor:
Ali Abbara, Sophie A. Clarke, Rosalind Brewster, Alexia Simonnard, Pei Chia Eng, Maria Phylactou, Deborah Papadopoulou, Chioma Izzi-Engbeaya, Amir H. Sam, Florian Wernig, Eliza Jonauskyte, Alexander N. Comninos, Karim Meeran, Tom W. Kelsey, Waljit S. Dhillo
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology
Frontiers in Endocrinology
The Section of Endocrinology and Investigative Medicine was funded by grants from the MRC, BBSRC, NIHR, an Integrative Mammalian Biology (IMB) Capacity Building Award, an FP7- HEALTH- 2009- 241592 EuroCHIP grant and was supported by the NIHR Biomedic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222c3aea6aeff0df19057961136a3fc6
https://hdl.handle.net/10023/19930
https://hdl.handle.net/10023/19930
Autor:
S.W. Kamerling, Ton J. Rabelink, Paul L A van Daele, Tom W J Huizinga, Argho Ray, T. Kraaij, Jaap A. Bakker, Cees van Kooten, O.W. Bredewold, Laura van Dam, Hans Scherer, Y.K. Onno Teng, Eline J Arends
Publikováno v:
Poster presentations.
Background Anti-CD20 B-cell depletion has not shown superior efficacy to standard immunosuppression in patients with systemic lupus erythematosus (SLE). Besides trial design, potential explanations are incomplete B-cell depletion in relation to subst
Autor:
Meriem Manai, Henriët van Middendorp, Tom W J Huizinga, Joy A. van der Pol, Dieuwke S. Veldhuijzen, Andrea W M Evers
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-10 (2020)
Trials
Trials, 21(1). BMC
Trials, 21
Trials, 21, 1
Trials, 21, 15
Trials
Trials, 21(1). BMC
Trials, 21
Trials, 21, 1
Trials, 21, 15
Background In pharmacological conditioning associations are formed between the effects of medication and contextual factors related to the medication. Pharmacological conditioning with placebo medication can result in comparable treatment effects and
Autor:
Tom W J Huizinga, R.J. Goekoop, Anne A. Schouffoer, Thomas Vogl, Cornelia F Allaart, Emma C. de Moel, Diane van der Woude, Jürgen Rech, Johannes Roth, René E. M. Toes, Georg Schett, Michael Mahler
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-8 (2019)
Arthritis Research & Therapy
Arthritis Research and Therapy, 21(1). BMC
Arthritis Research & Therapy
Arthritis Research and Therapy, 21(1). BMC
Objective To investigate whether calprotectin (S100A8/A9 or MRP8/14), an inflammatory complex released by monocytes, could indicate residual subclinical inflammation in rheumatoid arthritis (RA) patients who are in stable remission on disease-modifyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc9b23f01000bdf0182371f41f22aec
https://doi.org/10.1186/s13075-019-2064-y
https://doi.org/10.1186/s13075-019-2064-y