Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Qing-Yu He"'
Autor:
Yidong Zhu, Ang Li, Can-Can Zheng, Yan-Ming Yang, Long Liao, Yan He, Xing-Feng Yin, Yiyao Liang, Xiaomei Yu, Bin Li, Ding-Kang Wang, Qing-Yu He
Publikováno v:
Acta Pharmaceutica Sinica B. 12:1271-1287
As one of the hallmarks of cancer, metabolic reprogramming leads to cancer progression, and targeting glycolytic enzymes could be useful strategies for cancer therapy. By screening a small molecule library consisting of 1320 FDA-approved drugs, we fo
Publikováno v:
Journal of Proteome Research. 20:2839-2850
The unreasonable misuse of antibiotics has led to the emergence of large-scale drug-resistant bacteria, seriously threatening human health. Compared with drug-sensitive bacteria, resistant bacteria are difficult to clear by host immunity. To fully ex
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-11 (2020)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Esophageal cancer (EC) is one of the most lethal cancers in the world, and its morbidity and mortality rates rank among the top ten in China. Currently, surgical resection, radiotherapy and chemotherapy are the primary clinical treatments for esophag
Autor:
Shiqin Liu, Qing-Yu He, Linlin Cao, Xuesong Sun, Jian-Fang Huang, Dong-Hong Yang, Ruiguang Ge, Yun-Dan Zheng
Publikováno v:
Biochemical and biophysical research communications. 530(1)
Bacterial resistance has become a serious threat to human health. In particular, the gradual development of resistance to polymyxins, the last line of defense for human infections, is a major issue. Secreted proteins contribute to the interactions be
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 138, Iss, Pp 111442-(2021)
The incidence and prevalence of inflammatory bowel disease (IBD) are increasing worldwide. Current approved medication for IBD treatment in the clinic mainly includes corticosteroids and neutralization antibodies to pro-inflammatory cytokines. Howeve
Autor:
Wen Wen Xu, Qing-Yu He, Pan Hong, Jie Yang, Hui-Fang Hu, Qi-Hua Zhang, Fei Ye, Xin Yan, Bin Li, Xiao-Hui Huang
Publikováno v:
Cancer letters. 451
Vemurafenib is a B-Raf V600E inhibitor that exerts significant inhibitory effects in melanoma but not in colon cancer, and the mechanism of vemurafenib resistance remains unclear. In this study, bioinformatics analysis of gene profiles in cancer cell
Autor:
Annie L.M. Cheung, Qing-Yu He, YY Li, Hiu Fung Yuen, Simon Law, Kwok Wah Chan, Nikki P. Lee, Xin Yuan Guan, W Xu, Bin Li, Kin Tak Chan, Sai Wah Tsao, Yan Ru Qin, Pui Ying Tam
Publikováno v:
Clinical Cancer Research. 22:1243-1255
Purpose: Chemoresistance is a major obstacle in cancer therapy. We found that fluorouracil (5-FU)-resistant esophageal squamous cell carcinoma cell lines, established through exposure to increasing concentrations of 5-FU, showed upregulation of Id1,
Autor:
Hua-Xin Liao, Qing-Yu He, Wang Yueming, Wen-You Chen, Wen Wen Xu, Qing-Sheng Yang, Yun-Na Huang, Can-Can Zheng, Jia-Yi Ren, Bin Li
Publikováno v:
Journal of agricultural and food chemistry. 66(35)
A library consisting of 429 food-source compounds was used to screen the natural products with anticancer properties in esophageal squamous cell carcinoma (ESCC). We demonstrated for the first time that synephrine, an active compound isolated from le
Publikováno v:
Scopus-Elsevier
Streptococcus pneumoniae is a gram-positive pathogen that causes otitis media, pneumonia, meningitis, and other serious diseases. Vancomycin is one of the most important drugs currently used for the treatment of gram-positive bacterial infections, re
Publikováno v:
Frontiers of Biology in China. 4:392-401
Streptococcus is a genus of spherical Gram-positive bacteria responsible for many cases of meningitis, bacterial pneumonia, endocarditis, erysipelas, and necrotizing fasciitis. To survive in the host environment with limited free iron available, Stre