Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Klaas Nicolay"'
Publikováno v:
Investigative Radiology, 52(10), 620-630. Lippincott Williams and Wilkins Ltd.
Objectives: Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is a method to heat lesions noninvasively to a stable, elevated temperature and a well-suited method to induce local hyperthermia (41 degrees C-43 degrees C) in deep-se
Publikováno v:
Investigative Radiology. 51:735-745
Objectives Drug-loaded temperature-sensitive liposomes (TSLs) allow heat-triggered local drug delivery to tumors. When magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is applied to heat up the tumor, corelease of a drug together
Autor:
Bastiaan J. van Nierop, Coert J. Zuurbier, Sander M. Houten, Adrianus J. Bakermans, Inge van der Kroon, Antonius Baartscheer, Cees A. Schumacher, Klaas Nicolay, Jeanine J. Prompers, Gustav J. Strijkers, Anneke Koeman, Desiree Abdurrachim
Publikováno v:
NMR in Biomedicine. 28:1218-1227
(31)P MRS provides a unique non-invasive window into myocardial energy homeostasis. Mouse models of cardiac disease are widely used in preclinical studies, but the application of (31)P MRS in the in vivo mouse heart has been limited. The small-sized,
Autor:
Jolita Ciapaite, Klaas Nicolay, Jeanine J. Prompers, Bart Wessels, N.M.A. van den Broek, Sander M. Houten
Publikováno v:
Diabetes, Obesity and Metabolism, 17(1), 52-60. Wiley-Blackwell
Diabetes, obesity & metabolism, 17(1), 52-60. Wiley-Blackwell
Diabetes obesity & metabolism, 17(1), 52-60. Wiley
Diabetes, obesity & metabolism, 17(1), 52-60. Wiley-Blackwell
Diabetes obesity & metabolism, 17(1), 52-60. Wiley
Aim To determine the effect of pioglitazone treatment on in vivo and ex vivo muscle mitochondrial function in a rat model of diabetes. Methods Both the lean, healthy rats and the obese, diabetic rats are Zucker Diabetic Fatty (ZDF) rats. The homozygo
Autor:
Adrianus J. Bakermans, Sander M. Houten, Desiree Abdurrachim, Tom R. Geraedts, Klaas Nicolay, Jeanine J. Prompers
Publikováno v:
Magnetic Resonance in Medicine. 73:2069-2074
Purpose Proton magnetic resonance spectroscopy (1H-MRS) for quantitative in vivo assessment of mouse myocardial metabolism requires accurate acquisition timing to minimize motion artifacts and corrections for T1-dependent partial saturation effects.
Autor:
Erin Moshier, Masakatsu Kotsuma, Klaas Nicolay, Sotirios Tsimikas, Zahi A. Fayad, Jessica S. Mounessa, Esad Vucic, Sarayu Ramachandran, Karen Brown, Matthew J. Moon, James H.F. Rudd, Edward A. Fisher, Jan Bucerius, Claudia Calcagno, Michelle Roytman, James Lin, Stephen D. Dickson, Tatsuo Tanimoto, Katsumi Hayashi, Valentin Fuster
Publikováno v:
JACC: Cardiovascular Imaging. 5:819-828
Objectives The aim of this study was to noninvasively detect the anti-inflammatory properties of the novel liver X receptor agonist R211945. Background R211945 induces reversal cholesterol transport and modulates inflammation in atherosclerotic plaqu
Autor:
Klaas Nicolay, Claudia Calcagno, Sotirios Tsimikas, Valentin Fuster, James Lin, Stephen D. Dickson, Matthew J. Moon, James H.F. Rudd, Katsumi Hayashi, Erin Moshier, Edward A. Fisher, Esad Vucic, Michelle Roytman, Jessica S. Mounessa, Zahi A. Fayad
Publikováno v:
JACC: Cardiovascular Imaging. 4:1100-1109
Objectives We sought to determine the antiatherosclerotic properties of pioglitazone using multimethod noninvasive imaging techniques. Background Inflammation is an essential component of vulnerable or high-risk atheromas. Pioglitazone, a peroxisome
Autor:
Jolita Ciapaite, N.M.A. van den Broek, Sander M. Houten, Ron J. A. Wanders, Jeroen A. L. Jeneson, Klaas Nicolay, Jeanine J. Prompers, H.M.M.L. de Feyter
Publikováno v:
FASEB journal, 24(5), 1354-1364. FASEB
The FASEB Journal, 24(5), 1354-1364. FASEB
The FASEB Journal, 24(5), 1354-1364. FASEB
Mitochondria are thought to play a crucial role in the etiology of muscle insulin resistance (IR). The aim of this study was to gain more insight into the timing and nature of mitochondrial adaptations during the development of high-fat-diet (HFD)-in
Autor:
Alnawaz Rehemtulla, Linda A. Snyder, Craig J. Galbán, Thomas L. Chenevert, Sudha Sud, Kenneth J. Pienta, Chris K. Neeley, Stefan Rozel, Kuei C. Lee, Brian D. Ross, Klaas Nicolay
Publikováno v:
Journal of Cellular Biochemistry, 107(1), 58-64. Wiley-Liss Inc.
Metastatic prostate cancer continues to be the second leading cause of cancer death in American men with an estimated 28,660 deaths in 2008. Recently, monocyte chemoattractant protein-1 (MCP-1, CCL2) has been identified as an important factor in the
Autor:
Sander M. Houten, Nicole M. A. van den Broek, Bart Wessels, Klaas Nicolay, Jeanine J. Prompers, Ronald J.A. Wanders, Jolita Ciapaite
Publikováno v:
American Journal of Physiology : Endocrinology and Metabolism, 309(7), E670-E678. American Physiological Society
American Journal of Physiology-Endocrinology and Metabolism, 309(7), E670-E678. AMER PHYSIOLOGICAL SOC
American journal of physiology. Endocrinology and metabolism, 309(7), E670-E678. American Physiological Society
American Journal of Physiology-Endocrinology and Metabolism, 309(7), E670-E678. AMER PHYSIOLOGICAL SOC
American journal of physiology. Endocrinology and metabolism, 309(7), E670-E678. American Physiological Society
Muscle lipid overload and the associated accumulation of lipid intermediates play an important role in the development of insulin resistance. Carnitine insufficiency is a common feature of insulin-resistant states and might lead to incomplete fatty a