Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kadri Kõiv"'
Publikováno v:
Brain Sciences, Vol 11, Iss 470, p 470 (2021)
Brain Sciences
Brain Sciences
Fifty-kHz ultrasonic vocalizations (USVs) in response to an imitation of rough-and-tumble play (‘tickling’) have been associated with positive affective states and rewarding experience in the rat. This USV response can be used as a measure of int
Autor:
Jaanus Harro, Marten Vares, Kai Tiitsaar, Mait Metelitsa, Kadri Kõiv, Margit Kaldmäe, Karita Laugus, Ruth Shimmo
Publikováno v:
Pharmacology Biochemistry and Behavior. 171:10-19
High level of positive affectivity acts as a protective factor against adverse effects of stress and decreases vulnerability to mood disorders and drug abuse. Fifty-kHz ultrasonic vocalizations (50-kHz USV) index the level of positive affect in the r
Publikováno v:
Pharmacological Research. 113:739-746
In the studies of depression pathogenesis and antidepressant action, the monoaminergic hypothesis of depression has mainly focused on the serotonergic and noradrenergic mechanisms. However, dopaminergic neurotransmission is also linked to both depres
Autor:
Mait Metelitsa, Jaanus Harro, Külli Jaako, Marten Vares, Kai Tiitsaar, Cristina Kroon, Kadri Kõiv, Karita Laugus
Publikováno v:
Journal of psychopharmacology (Oxford, England). 33(12)
Background:Individual vulnerability to stress manifests in the interaction of innate properties and environment. There is a growing interest in the individual variability in vulnerability to stress and how it contributes to the development of psychia
Autor:
Kaspar Vulla, Kai Tiitsaar, Karita Raudkivi, Kadri Kõiv, Ruth Shimmo, Mait Metelitsa, Jaanus Harro, Marten Vares, Külli Jaako
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 26(4)
The relationship between stress response and positive affective states is thought to be bidirectional: whilst stress can lead to a blunted hedonic response, positive affect reduces the negative effects of stress. We have previously shown that persist
Publikováno v:
Synapse. 63:443-446
Increases in both striatal dopamine release and the proportion of the D2 receptors in the high affinity state (D) accompany the behavioral sensitization to psychostimulants, but it is not known whether the physiological substrate of the interindividu
Publikováno v:
Behavioural Brain Research. 177:269-281
Behaviour in novel environments is influenced by the conflicting motivators fear and curiosity. Because changes in both of these motivational processes are often simultaneously involved in human affective disorders, we have developed the exploration
Autor:
Jaanus Harro, Mait Metelitsa, Kadri Kõiv, Karita Raudkivi, Kai Tiitsaar, C. Kroon, A. Paesüld
Publikováno v:
European Neuropsychopharmacology. 26:S248
Publikováno v:
Behavioural brain research. 216(1)
The potential contribution of locus coeruleus (LC)-derived noradrenaline (NA) in the motor activating and rewarding effects of cocaine (15 mg/kg) were assessed following administration of the neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (D
Publikováno v:
Neuroscience. 132(4)
Individual differences in behavioral traits are associated with sensitivity to various neurochemical and psychopharmacological manipulations. In this study exploratory and amphetamine-induced behavior in rats with persistently high or low exploratory