Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Formisano A"'
Autor:
Fabiana Napolitano, Sabino De Placido, Lucia Maresca, Antonio Santaniello, R. Marciano, Roberto Bianco, Eleonora Mozzillo, Alberto Servetto, Francesca Foschini, Luigi Formisano, Priscilla Cascetta, Pietro De Placido, Anna Rita Amato, Maria Rosaria Augurio
Publikováno v:
Cancers, Vol 13, Iss 4939, p 4939 (2021)
Cancers
Volume 13
Issue 19
Cancers
Volume 13
Issue 19
Patients with locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC) do not present distant metastases but are not eligible for surgery upfront. Chemotherapy regimens, such as FOLFIRINOX (FFN) or nab-paclitaxel plus gemcitabine (GemNab) in com
Autor:
Valerie M. Jansen, Yao Lu, Paula Gonzalez Ericsson, Wei He, Luis J. Schwarz, Richard B. Lanman, Dhivya R. Sudhan, Yu Shyr, Teresa C. Dugger, Yan Guo, Carlos L. Arteaga, Marcelo Rocha Cruz, Alberto Servetto, Ingrid A. Mayer, Amir Behdad, Aditya Bardia, Luigi Formisano, Sarah Croessmann, Nadia Solovieff, Angel Guerrero-Zotano, Fei Su, Michelle Miller, Justin M. Balko, Mellissa J. Nixon, Joyce O'Shaughnessy, Ariella B. Hanker, Kyungmin Lee, Melinda E. Sanders, Massimo Cristofanilli, Joshua A. Bauer, Rebecca J. Nagy
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Using an ORF kinome screen in MCF-7 cells treated with the CDK4/6 inhibitor ribociclib plus fulvestrant, we identified FGFR1 as a mechanism of drug resistance. FGFR1-amplified/ER+ breast cancer cells and MCF-7 cells transduced with FGFR1 were resista
Autor:
Mellissa J. Nixon, Sarah Croessmann, Justin M. Balko, Carlos L. Arteaga, Paula Gonzalez Ericsson, Alshad S. Lalani, Melinda E. Sanders, Dhivya R. Sudhan, Francesca Avogadri-Connors, Angel Guerrero-Zotano, Alan Auerbach, Richard Bryce, Luigi Formisano, Luis J. Schwarz, Richard E. Cutler
Publikováno v:
Clinical Cancer Research. 25:771-783
Purpose:The phase III ExteNET trial showed improved invasive disease-free survival in patients with HER2+ breast cancer treated with neratinib versus placebo after trastuzumab-based adjuvant therapy. The benefit from neratinib appeared to be greater
Autor:
Roberta Marciano, Alberto Servetto, Concetta Di Mauro, Roberto Bianco, Luigi Formisano, Priscilla Cascetta, Pietro De Placido, Fabiana Napolitano, Ada Pesapane, Annachiara Carratù, Stefania Belli, Eleonora Mozzillo, Antonio Santaniello, Daniela Esposito
Publikováno v:
Cancer Research. 80:P3-06
Background: CDK4/6 inhibitors have been approved in combination with endocrine therapy for the treatment of estrogen receptor positive (ER+) metastatic breast cancer. The goal of this study was to discover mechanisms of resistance to ER antagonists a
Autor:
Giuseppe Caliendo, Giusy Mosca, Rosa Sparaco, Paola Massarelli, Teresa Migliaccio, Maria Rosaria Ambrosio, F. Fiorino, Vittoria D'Esposito, Elisa Magli, Pietro Formisano
Publikováno v:
BMC cancer. 22(1)
Background Serotonin (or 5-Hydroxytryptamine, 5-HT) signals in mammary gland becomes dysregulated in cancer, also contributing to proliferation, metastasis, and angiogenesis. Thus, the discovery of novel compounds targeting serotonin signaling may co
Autor:
Begoña Miras-Moreno, Youssef Rouphael, Luigi Formisano, Giandomenico Corrado, Luigi Lucini, Giuseppe Colla, Christophe El-Nakhel, Michele Ciriello
Publikováno v:
Agronomy, Vol 11, Iss 1205, p 1205 (2021)
Agronomy
Volume 11
Issue 6
Agronomy
Volume 11
Issue 6
Plant biostimulants are “green” solutions to improve crop production. Trichoderma spp. and phosphites, ordinarily used as biocontrol agents, can trigger phytostimulation, also promoting endogenous mechanisms involved in plant growth and developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1bd95832d396608cba792dcf8b1088
http://hdl.handle.net/11588/854108
http://hdl.handle.net/11588/854108
Nuclear FGFR1 regulates gene transcription and promotes antiestrogen resistance in ERþ breast cancer
Autor:
Ralf Kittler, Hiroaki Akamatsu, Saurabh Mendiratta, Carlos L. Arteaga, Paula I. Gonzalez-Ericsson, Dhivya R. Sudhan, Alberto Servetto, Nicholas G. James, Kyungmin Lee, Rahul K. Kollipara, Luigi Formisano, Ariella B. Hanker, Roberto Bianco, Sumanta Chatterjee, Chang-Ching Lin, Angel Guerrero-Zotano
Purpose: FGFR1 overexpression has been associated with endocrine resistance in ER+ breast cancer. We found FGFR1 localized in the nucleus of breast cancer cells in primary tumors resistant to estrogen suppression. We investigated a role of nuclear FG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1080233d81cac4445ec5def6aefe45db
http://hdl.handle.net/11588/877564
http://hdl.handle.net/11588/877564
Autor:
Paola Mirra, Antonella Desiderio, Francesca Chiara Pignalosa, Cecilia Nigro, Pietro Formisano, Luca Ulianich, Claudia Miele, Raffaele Napoli, Francesca Fiory, Giuseppe Perruolo, Francesco Beguinot
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12366, p 12366 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 12366, p 12366 (2021)
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia, responsible for the onset of several long-term complications. Recent evidence suggests that cognitive dysfunction represents an emerging complication of DM, but th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502227f1a1fdf06e5ba6a501c607d271
http://hdl.handle.net/11588/867673
http://hdl.handle.net/11588/867673
Publikováno v:
Journal of neuroscience research. 100(8)
Modulatory mechanisms of neurotransmitter release and clearance are highly controlled processes whose finely tuned regulation is critical for functioning of the nervous system. Dysregulation of the monoamine neurotransmitter dopamine can lead to seve
Autor:
Dino Franco Vitale, Adele Ferro, Francesco Baldascino, Stefania Paolillo, Roberto Formisano, Vittoria D'Esposito, Valentina Parisi, Pasquale Perrone Filardi, Laurent Davin, A. Caruso, Laura Petraglia, Antonio De Bellis, Maria Gabriella Grimaldi, Giuseppe Rengo, Serena Cabaro, Nicola Ferrara, Dario Leosco, Pietro Formisano, Patrizio Lancellotti
Publikováno v:
International journal of cardiology
274 (2019): 326–330. doi:10.1016/j.ijcard.2018.06.106
info:cnr-pdr/source/autori:Parisi V.; Petraglia L.; D'Esposito V.; Cabaro S.; Rengo G.; Caruso A.; Grimaldi M.G.; Baldascino F.; De Bellis A.; Vitale D.; Formisano R.; Ferro A.; Paolillo S.; Davin L.; Lancellotti P.; Formisano P.; Perrone Filardi P.; Ferrara N.; Leosco D./titolo:Statin therapy modulates thickness and inflammatory profile of human epicardial adipose tissue/doi:10.1016%2Fj.ijcard.2018.06.106/rivista:International journal of cardiology (print)/anno:2019/pagina_da:326/pagina_a:330/intervallo_pagine:326–330/volume:274
274 (2019): 326–330. doi:10.1016/j.ijcard.2018.06.106
info:cnr-pdr/source/autori:Parisi V.; Petraglia L.; D'Esposito V.; Cabaro S.; Rengo G.; Caruso A.; Grimaldi M.G.; Baldascino F.; De Bellis A.; Vitale D.; Formisano R.; Ferro A.; Paolillo S.; Davin L.; Lancellotti P.; Formisano P.; Perrone Filardi P.; Ferrara N.; Leosco D./titolo:Statin therapy modulates thickness and inflammatory profile of human epicardial adipose tissue/doi:10.1016%2Fj.ijcard.2018.06.106/rivista:International journal of cardiology (print)/anno:2019/pagina_da:326/pagina_a:330/intervallo_pagine:326–330/volume:274
BACKGROUND: Epicardial adipose tissue (EAT) thickness and pro-inflammatory status has been shown to be associated with several cardiac diseases, including aortic stenosis (AS). Thus, cardiac visceral fat could represent a potential new target for dru