Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Brooke Benner"'
Autor:
Carly Pilcher, Bhavana Konda, Manisha H. Shah, Robert Wesolowski, William E. Carson, Himanshu Savardekar, Claire F. Verschraegen, Logan Good, Gregory K. Behbehani, Brooke Benner, Christian Ghattas, Dwight H. Owen, Gregory A. Otterson, Ruthann Norman
Publikováno v:
Clin Lung Cancer
Structured Abstract: Background Immune checkpoint inhibitors are now an approved treatment for patients with extensive- stage small cell lung cancer (SCLC), an aggressive and incurable malignancy. However, the median survival for patients remains aro
Publikováno v:
Cancer Immunology, Immunotherapy
Bruton’s tyrosine kinase (BTK) is a non-receptor kinase belonging to the Tec family of kinases. The role of BTK in B cell receptor signaling is well defined and is known to play a key role in the proliferation and survival of malignant B cells. Mor
Autor:
Lianbo Yu, Nicholas B. Courtney, William E. Carson, Thomas A. Mace, Brooke Benner, Fouad Choueiry, David Abood, Megan C. Duggan, Elizabeth L. McMichael, Ashley Pinette
Publikováno v:
Cancer Immunol Immunother
Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer worldwide and epidermal growth factor receptor (EGFR) is overexpressed in greater than 90% of patient tumors. Cetuximab is a monoclonal antibody that binds to EGFR a
Autor:
S. Ferguson, Peter G. Shields, Dwight H. Owen, Carly Pilcher, Claire F. Verschraegen, Greg Otterson, Brooke Benner, M. Smith, Carolyn J Presley, Erin M. Bertino, Lai Wei, Bhavana Konda, William E. Carson, S. Mori Vogt, Manisha H. Shah, David P. Carbone, Ruthann Norman, Sandip H. Patel, Kai He
Publikováno v:
Journal of Thoracic Oncology. 16:S647
Autor:
Amanda Campbell, Akaansha Ganju, Stephen V. Liu, Sarvani Uppati, Kala M. Levine, Bonnie Paul, Tiffany Noel, Elizabeth L. McMichael, Gonzalo N. Olaverria Salavaggione, Panos Savvides, William E. Carson, Melanie E. Davis, Lakhvir S. Atwal, Michael A. Caligiuri, Theodoros N. Teknos, Nicholas B. Courtney, Thomas Olencki, Kallan Williams, Megan C. Duggan, Brooke Benner, Susheela Tridandapani, Kyle A. Martin, Xiaokui Mo, John C. Byrd
Publikováno v:
Clin Cancer Res
Purpose: mAbs including cetuximab can induce antibody-dependent cellular cytotoxicity (ADCC) and cytokine production mediated via innate immune cells with the ability to recognize mAb-coated tumors. Preclinical modeling has shown that costimulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fcefe11987d7a560074b271108d065
https://europepmc.org/articles/PMC6697573/
https://europepmc.org/articles/PMC6697573/
Autor:
Andrew Stiff, Brooke Benner, Megan C. Duggan, Susheela Tridandapani, William E. Carson, Luke Scarberry, Gabriella Lapurga, Logan Good, Jonathan P. Butchar
Publikováno v:
OncoImmunology, Vol 8, Iss 11 (2019)
Oncoimmunology
Oncoimmunology
An inflammatory microenvironment has been shown to play an important role in the growth and metastasis of tumors. The NLRP3 inflammasome is a multi-protein complex of the innate immune system that is responsible for the production of the potent infla